UV-C Light Completely Blocks Aerosol Transmission of Highly Contagious SARS-CoV-2 Variants WA1 and Delta in Hamsters

Article Microbiology

Increased small particle aerosol transmission of B.1.1.7 compared with SARS-CoV-2 lineage A in vivo

Julia R. Port et al.

Summary: The major transmission route for SARS-CoV-2 is airborne. Experimental evidence shows that the Alpha variant has a higher competition advantage in airborne transmission compared to lineage A.

NATURE MICROBIOLOGY (2022)

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Article Microbiology

A 265-Nanometer High-Power Deep-UV Light-Emitting Diode Rapidly Inactivates SARS-CoV-2 Aerosols

Hiroshi Ueki et al.

Summary: A high-power DUV-LED system has been developed, which can effectively inactivate SARS-CoV-2 within a short period of time. The inactivation effect is significantly higher for aerosolized SARS-CoV-2 compared to SARS-CoV-2 suspensions.

MSPHERE (2022)

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Article Engineering, Environmental

Greater than 3-Log Reduction in Viable Coronavirus Aerosol Concentration in Ducted Ultraviolet-C (UV-C) Systems

Yuechen Qiao et al.

Summary: The study demonstrates that sealed UV-C flow reactors efficiently inactivate coronaviruses in aerosols, making them suitable for incorporation into HVAC ducts or recirculating air purifiers.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2021)

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Article Infectious Diseases

Rapid, dose-dependent and efficient inactivation of surface dried SARS-CoV-2 by 254 nm UV-C irradiation

Natalia Ruetalo et al.

Summary: The study found that short exposure to UV-C irradiation can effectively reduce the infectivity of SARS-CoV-2 and confirmed the dose necessary to achieve at least a 6-log reduction in viral titres.

EUROSURVEILLANCE (2021)

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Article Multidisciplinary Sciences

ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7

Robert J. Fischer et al.

Summary: The study demonstrates the effectiveness of the ChAdOx1 nCoV-19 vaccine against clinical disease caused by B.1.1.7 or B.1.351 variants. Vaccinated hamsters did not experience weight loss or lung lesions compared to control animals after being challenged with the variants.

NATURE COMMUNICATIONS (2021)

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Editorial Material Medicine, General & Internal

Ten scientific reasons in support of airborne transmission of SARS-CoV-2

Trisha Greenhalgh et al.

LANCET (2021)

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Review Biochemistry & Molecular Biology

Air Disinfection for Airborne Infection Control with a Focus on COVID-19: Why Germicidal UV is Essential†

Edward A. Nardell

Summary: Aerosol transmission is recognized as the main way COVID-19 spreads, highlighting the importance of ventilation. Mechanical ventilation in non-healthcare settings may not achieve recommended air changes per hour. Upper room germicidal UV air disinfection is a key technology for reducing COVID-19 transmission.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2021)

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Article Microbiology

A human coronavirus evolves antigenically to escape antibody immunity

Rachel T. Eguia et al.

Summary: This study investigates the evolution of human coronavirus 229E and finds that as the virus evolves, mutations in the spike protein can escape neutralization by antibodies in old human sera. The results suggest that viral evolution may impact immunity, highlighting the need for periodic updates to coronavirus vaccines.

PLOS PATHOGENS (2021)

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Article Engineering, Environmental

Inactivation of Coronaviruses and Phage Phi6 from Irradiation across UVC Wavelengths

Ben Ma et al.

Summary: The study found that UVC devices can effectively inactivate enveloped viruses, with KrCl* excimer showing the best disinfection performance. Coronaviruses showed similar sensitivities to UV irradiation across different UVC wavelengths, while the bacteriophage surrogate was more resistant and exhibited higher sensitivity to Far UVC irradiation.

ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS (2021)

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Editorial Material Medicine, General & Internal