4.5 Review

Recent advances and challenges in temperature monitoring and control in microfluidic devices

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Thermodynamics

Self-adaptive cooling of chips with unevenly distributed high heat fluxes

Xiu Li et al.

Summary: The proposed self-adaptive cooling technique effectively addresses unevenly distributed high heat fluxes and enhances near-wall flow by adjusting flow distribution. This technology can effectively reduce temperatures and reduce total flow rates by an order of magnitude.

APPLIED THERMAL ENGINEERING (2022)

Article Engineering, Biomedical

Microheater: material, design, fabrication, temperature control, and applications-a role in COVID-19

Z. E. Jeroish et al.

Summary: Heating plays a vital role in various fields such as science, engineering, mining, and space, and the miniaturization of heaters has become an important research area. This review provides an overview of recent advancements in microheaters, analyzes different designs, materials, fabrication, and temperature control methods, and emphasizes their applications in gas sensing, biological, and electrical and mechanical sectors.

BIOMEDICAL MICRODEVICES (2022)

Review Biochemical Research Methods

Electrically driven microfluidic platforms for exosome manipulation and characterization

Gladys G. Diaz-Armas et al.

Summary: This review focuses on the state-of-the-art electrical techniques and methods for manipulating and detecting exosomes in microfluidic devices. While there are numerous reviews on exosome separation using benchtop equipment like ultracentrifugation, there is a lack of reviews specifically addressing the use of electrical phenomena in microfluidic devices for exosome manipulation and detection. Highlights from the past decade and future perspectives for this research field are presented, outlining challenges to be addressed in the coming years.

ELECTROPHORESIS (2022)

Article Biochemical Research Methods

Miniaturized and IoT Enabled Continuous-Flow-Based Microfluidic PCR Device for DNA Amplification

Madhusudan B. Kulkarni et al.

Summary: In this study, a continuous-flow driven microfluidic device for polymerase chain reaction (PCR) was designed and fabricated using the CO2 laser ablation method. The device, with low-cost, battery-powered, automated, integrated, and IoT-enabled features, achieved accurate temperature control for PCR reactions in two thermal zones. The device demonstrated excellent performance in amplification of DNA template and was compared to the conventional PCR instrument.

IEEE TRANSACTIONS ON NANOBIOSCIENCE (2022)

Article Multidisciplinary Sciences

Thermally controlled microfluidic back pressure regulator

Karolina Svensson et al.

Summary: This paper introduces a novel microfluidic lab-on-a-chip back pressure regulator that uses the temperature dependence of viscosity to control flow resistance and achieve precise pressure regulation. The regulator has a small dead volume and fast thermal actuation.

SCIENTIFIC REPORTS (2022)

Article Biophysics

An internet of things-based point-of-care device for direct reverse-transcription-loop mediated isothermal amplification to identify SARS-CoV-2

Huynh Quoc Nguyen et al.

Summary: The urgent need for rapid and accurate testing tools for SARS-CoV-2 detection can be met by IoT-based diagnostic devices, which can provide real-time monitoring with high sensitivity and accuracy.

BIOSENSORS & BIOELECTRONICS (2022)

Article Thermodynamics

Improvement of flow and heat transfer performance of manifold microchannel with porous fins

Chaowei Chen et al.

Summary: This study investigates the flow and heat transfer characteristics of MMC with porous fins using numerical methods, showing that the introduction of porous fins can reduce pressure drop, optimize non-uniform flow distribution, and enhance heat transfer efficiency.

APPLIED THERMAL ENGINEERING (2022)

Article Thermodynamics

Time-dependent heat transfer analysis of ellipsoidal protruded microchannel with multiple pulsating jets

Xinyue Huang et al.

Summary: This study investigates the heat transfer enhancement and thermal performance improvement by considering the advantages of unsteady properties and ellipsoid protrusions in microchannels. Multiple pulsating jets with velocity phase difference are applied, leading to significant fluctuations in mass flow rate and temperature distribution. The heat transfer enhancement is most prominent at a phase difference of 0.75.pi, and the thermal performance reaches its maximum value at the same phase difference. The periodic adjustment of jet velocities weakens the adverse effects of cross flow and effectively suppresses the drift phenomenon.

APPLIED THERMAL ENGINEERING (2022)

Article Engineering, Mechanical

Simultaneous velocity profile and temperature profile measurements in microfluidics

Florian Burkle et al.

Summary: This study combines Laser Doppler Velocity Profile Sensor (LDV-PS) with Laser-Induced Fluorescence (LIF) to solve the problem of simultaneous non-intrusive temperature and velocity measurements in flows. In an air flow experiment, relative velocity uncertainties of 0.4% and temperature uncertainties of 0.24°C with a spatial resolution of 10 μm are achieved. The method has the potential to be applied in various thermal flows and improve the energy efficiency of microfluidic devices.

FLOW MEASUREMENT AND INSTRUMENTATION (2022)

Article Chemistry, Analytical

An integrated microfluidic platform featuring real-time reverse transcription loop-mediated isothermal amplification for detection of COVID-19

You-Ru Jhou et al.

Summary: An integrated microfluidic platform utilizing real-time reverse-transcription loop-mediated isothermal amplification was developed for detection and quantification of three genes of SARS-CoV-2, providing a useful tool for COVID-19 diagnostics.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

Article Chemistry, Analytical

Microfluidics Temperature Compensating and Monitoring Based on Liquid Metal Heat Transfer

Jiyu Meng et al.

Summary: In this study, the relationship between microfluids and the glass substrate in microfluidic devices was investigated. With an intelligent structure design and liquid metal, temperature sensing of micro-scale fluids using a millimeter-scale industrial temperature sensor was demonstrated. The proposed heat transfer model and temperature control method showed excellent performance in temperature-sensitive experiments.

MICROMACHINES (2022)

Article Chemistry, Physical

Emerging trends in miniaturized and microfluidic electrochemical sensing platforms

Jaligam Murali Mohan et al.

Summary: Electrochemical sensing has significant applications in various areas and can provide rapid analysis with a disposable, reusable, and cost-effective platform by integrating miniaturized and microfluidic devices. The recent advancements include the integration of automation and Internet of Things to realize fully automated and robust electrochemical microdevices.

CURRENT OPINION IN ELECTROCHEMISTRY (2022)

Article Chemistry, Analytical

Ultrafast DNA Amplification Using Microchannel Flow-Through PCR Device

Yen-Heng Lin et al.

Summary: This study develops an ultrafast PCR platform using flow-through microchannel chips, which can complete PCR reactions in a short time. Experimental results show that the design of channel height and length has a significant impact on reaction speed and result stability.

BIOSENSORS-BASEL (2022)

Article Thermodynamics

A Self-generated Chemotaxis-inspired routing method for digital microfluidic cooling of hotspots in integrated circuits

Maohua Chen et al.

Summary: The study introduces a droplet route optimization method inspired by self-generated chemotaxis, aiming to efficiently cool the hot spots inside 3DICs. Numerical results demonstrate the effectiveness of the method in searching multiple hot spots and routing multiple droplets simultaneously.

ENERGY CONVERSION AND MANAGEMENT (2022)

Article Engineering, Electrical & Electronic

Integrated cooling system for microfluidic PDMS devices used in biological microscopy studies

Zahra Khaji et al.

Summary: This study integrated a water-based cooling system into a microfluidic device for cooling living cells to single-digit temperatures without interfering with the cells themselves, suitable for single-cell biological studies. Results showed stable on-chip cooling can be achieved under specific parameters, demonstrating the system's effectiveness for live cell culture experiments.

JOURNAL OF MICROMECHANICS AND MICROENGINEERING (2022)

Article Biochemical Research Methods

Joule heating-enabled electrothermal enrichment of nanoparticles in insulator-based dielectrophoretic microdevices

Amirreza Malekanfard et al.

Summary: Insulator-based dielectrophoresis (iDEP) utilizes electric field gradients around insulating structures to manipulate particles, with the potential to trap and concentrate nanoparticles in a ratchet-based iDEP microdevice. The electrothermal flow circulations generated from locally amplified Joule heating are found to be more effective with increasing electric field strength, especially for larger particles and in microchannels with symmetric ratchets.

ELECTROPHORESIS (2021)

Article Chemistry, Analytical

Microwave Heating Induced On-Demand Droplet Generation in Microfluidic Systems

Weijia Cui et al.

Summary: The method uses integrated microwave heating to induce droplet generation, with the distance between interface and junction and microwave power affecting the process. Despite limitations in droplet generation rate, integration with microwave sensing allows for dynamic tuning of material properties.

ANALYTICAL CHEMISTRY (2021)

Article Biochemical Research Methods

Joule heating effects on electrokinetic flows with conductivity gradients

Le Song et al.

Summary: This study presents the first exploration of Joule heating effects in electrokinetic microchannel flows with conductivity gradients, revealing that Joule heating increases the critical electric field for electrokinetic instability and leads to a smaller electric Rayleigh number.

ELECTROPHORESIS (2021)

Article Computer Science, Hardware & Architecture

An industrial IoT sensor system for high-temperature measurement

Victor Chang et al.

Summary: This paper presents the design and implementation of an Arduino sensor system used to record the temperature and location of ladle vessels for metallurgical purposes. The system, with multiple modules connected, was fully tested to demonstrate its stability and accuracy, potentially contributing to the development of Industrial IoT and smart sensor services.

COMPUTERS & ELECTRICAL ENGINEERING (2021)

Article Biochemical Research Methods

Harnessing Joule heating in microfluidic thermal gel electrophoresis to create reversible barriers for cell enrichment

Mario A. Cornejo et al.

Summary: This study presents a method to enrich cells within a microfluidic gel, utilizing thermal gels that can reversibly convert between liquid and solid phases. By controlling Joule heating to regulate the phase of the gel, cells can be enriched for downstream analyses with minimal dilution and degradation. This innovative approach offers a cost-effective solution for in-gel cell enrichment in microfluidic devices.

ELECTROPHORESIS (2021)

Article Thermodynamics

Thermal management and temperature uniformity enhancement of electronic devices by micro heat sinks: A review

Ziqiang He et al.

Summary: Micro heat sinks are crucial for addressing the challenges of high heat flux and non-uniform temperature distribution in electronic devices. Developments in thermal enhancement technologies and reducing non-uniform temperature distribution are essential. An effective adaptive cooling method is urgently needed to improve the efficiency and lifespan of electronic components.

ENERGY (2021)

Article Food Science & Technology

Microfluidic devices for multiplexed detection of foodborne pathogens

Xiaoying Han et al.

Summary: The global burden of foodborne diseases is significant, with foodborne pathogens being the major cause of human illnesses. Microfluidic technology enables rapid, cost-effective, sensitive, and portable pathogen detection to meet on-site testing requirements. Multiplexed detection technology offers a new opportunity to ensure food safety by simultaneously detecting multiple pathogens.

FOOD RESEARCH INTERNATIONAL (2021)

Article Nanoscience & Nanotechnology

A smart microfluidic-based fish farm for zebrafish screening

Karthick Mani et al.

Summary: This study introduces a smart microfluidic device that enables efficient temperature control, remote zebrafish transport, perfusion, and dynamic culturing all together, providing the potential for on-chip high-quality imaging.

MICROFLUIDICS AND NANOFLUIDICS (2021)

Article Thermodynamics

Microfluidic Concentration Enhancement of Bio-Analyte by Temperature Gradient Focusing via Joule Heating by DC Plus AC Field: A Numerical Approach

Amitava Dutta et al.

Summary: The study provides a detailed numerical analysis on the electrophoresis induced concentration of a bio-analyte facilitated by temperature gradient focusing (TGF) in a phosphate buffer solution. The effects of AC field frequency and channel width variation on the concentration of the target analyte are investigated. The research demonstrates the potential for achieving high concentration of target analyte under specific conditions through the technique.

JOURNAL OF THERMAL SCIENCE AND ENGINEERING APPLICATIONS (2021)

Article Energy & Fuels

Screening High-Temperature Foams with Microfluidics for Thermal Recovery Processes

Thomas W. de Haas et al.

Summary: Thermal recovery processes such as SAGD are commonly used for bitumen extraction. Co-injecting foaming surfactants with noncondensable gases along with steam can improve steam chamber behavior, and microfluidics is a useful tool for evaluating surfactant performance at relevant conditions.

ENERGY & FUELS (2021)

Article Nanoscience & Nanotechnology

An inexpensive, versatile, compact, programmable temperature controller and thermocycler for simultaneous analysis and visualization within a microscope

Pablo Martinez Cruz et al.

Summary: The study presents an inexpensive, modular, compact, and user-friendly temperature control system that operates within a microscope, providing precise temperature acquisition and control. Consisting of a Device Holder and a Control Device, the system allows for heating and cooling operations at different temperatures, with real-time data visualization through a Bluetooth smartphone application. The system's utility was demonstrated by monitoring fluorescence in a microfluidic device and performing PCR within a microscope, showing potential impact across a wide range of applications requiring simultaneous imaging and temperature control.

MICROFLUIDICS AND NANOFLUIDICS (2021)

Article Engineering, Aerospace

A Numerical Study on Condensation Heat Transfer Characteristics of R134a in Microchannel Under Varying Gravity Conditions

Prasenjit Dey et al.

Summary: Using condensation technique can dissipate a large amount of heat more efficiently than using the sensible heat of coolant, and cooling by microchannel is more promising than conventional channel. Condensation in a microchannel under different gravity conditions significantly influences fluid flow and heat transfer characteristics.

MICROGRAVITY SCIENCE AND TECHNOLOGY (2021)

Article Chemistry, Analytical

Heater Integrated Lab-on-a-Chip Device for Rapid HLA Alleles Amplification towards Prevention of Drug Hypersensitivity

Shah Mukim Uddin et al.

Summary: A heater-integrated lab-on-a-chip device was developed for rapid detection of HLA-B alleles, showing complete concurrence with the traditional tube assay.

SENSORS (2021)

Article Chemistry, Analytical

A high-precision thermometry microfluidic chip for real-time monitoring of the physiological process of live tumour cells

Xuefei Zhao et al.

Summary: This study successfully integrated a high-precision platinum thermo-sensor into a microfluidic chip for cell culture and in situ monitoring of cellular temperature. The microchip showed good sensitivity and linear correlation between temperature and resistance of the Pt sensor in a range of 20-40 degrees C. The findings demonstrate the potential of this thermometric microchip for label-free monitoring of cellular temperature in physiology and pathology studies.

TALANTA (2021)

Review Chemistry, Analytical

Thermal droplet microfluidics: From biology to cooling technology

Asmaa Khater et al.

Summary: Droplet microfluidic platforms have made significant progress in chemical, biological, and medical applications by controlling droplet temperature and enabling multi-functional droplet operations. They can be applied in various medical, chemical, and engineering fields through precise manipulation and offer new methods to meet different demands.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2021)

Article Engineering, Electrical & Electronic

An on-skin platform for wireless monitoring of flow rate, cumulative loss and temperature of sweat in real time

Kyeongha Kwon et al.

Summary: The platform presented in the study enables real-time monitoring of sweat parameters by combining a short fluid passage and a flow sensor. Data is transferred wirelessly using a Bluetooth Low Energy system on a chip, and it can also integrate with microfluidic systems and colorimetric chemical reagents for multi-parameter measurements.

NATURE ELECTRONICS (2021)

Article Engineering, Mechanical

New cost effective design of PCR heating cycler system using Peltier plate without the conventional heating block

Gamal A. Nasser et al.

Summary: Temperature control is crucial in PCR for efficient DNA amplification, aiming for tight control and high rate of heating and cooling. This paper presents a cost-effective PCR heating/cooling system using Peltier element controlled by adaptive FLC with bang-bang as a hybrid controller, achieving good accuracy and fast temperature changing rate.

JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY (2021)

Article Nanoscience & Nanotechnology

Miniaturized DNA amplification platform with soft-lithographically fabricated continuous-flow PCR microfluidic device on a portable temperature controller

Madhusudan B. Kulkarni et al.

Summary: Continuous-flow microfluidic PCR allows fast thermal cycling and multiplexing using small volume, while reducing reaction time and device size.

MICROFLUIDICS AND NANOFLUIDICS (2021)

Article Hematology

Multiparameter microfluidics assay of thrombus formation reveals increased sensitivity to contraction and antiplatelet agents at physiological temperature

Linda Herfs et al.

Summary: This study demonstrated the advantage of multiparameter assessment of platelet traits at physiological temperature in detecting acquired platelet dysfunction. Results showed that higher temperature enhanced platelet adhesion and aggregation, particularly in the formation of contracted thrombi.

THROMBOSIS RESEARCH (2021)

Article Engineering, Electrical & Electronic

A microfluidic chip carrier including temperature control and perfusion system for long-term cell imaging

Federico Cantoni et al.

Summary: The presented carrier is a cost-effective option for maintaining physiological conditions of microfluidic chips while minimizing device manipulation. By integrating a perfusion system and a film resistive heater, the carrier can sustain the environmental conditions and temperature of the microfluidic chips.

HARDWAREX (2021)

Article Biochemical Research Methods

Bacterial classification and antibiotic susceptibility testing on an integrated microfluidic platform

Alexandros A. Sklavounos et al.

Summary: This study demonstrated a method for bacterial classification and antibiotic susceptibility testing using digital microfluidics, achieving automated and simultaneous results in under 18 hours through monitoring metabolic markers. The versatility and accuracy of this method were shown through successful identification of bacteria and validation of AST results.

LAB ON A CHIP (2021)

Article Engineering, Aerospace

Joule heating and viscous dissipation effect on electroosmotic mixed convection flow in a vertical microchannel subjected to asymmetric heat fluxes

Michael O. Oni et al.

Summary: This article investigates the impact of Joule heating due to electric double layer and viscous dissipation on electroosmotic mixed convection flow in a vertical microchannel. Mathematical modeling and computations reveal the variations in velocity profile and temperature distribution under different conditions.

PROPULSION AND POWER RESEARCH (2021)

Article Biochemical Research Methods

A microscopy-compatible temperature regulation system for single-cell phenotype analysis - demonstrated by thermoresponse mapping of microalgae†

Martin Andersson et al.

Summary: This work presents a programmable heat-stage designed for microfluidic devices, which allows precise control of temperature to study the photophysiological responses of coral symbionts. The device can provide biologically relevant temperature profiles while demonstrating the thermal sensitivity and acclimatization of Symbiodinium cells under different exposure conditions. The results suggest potential applications in biotechnology and ecotoxicology.

LAB ON A CHIP (2021)

Article Computer Science, Interdisciplinary Applications

Benchmark temperature microcontroller for process dynamics and control

Junho Park et al.

COMPUTERS & CHEMICAL ENGINEERING (2020)

Article Chemistry, Analytical

Microfluidic Point-of-Care Devices: New Trends and Future Prospects for eHealth Diagnostics

Jorge Ricardo Mejia-Salazar et al.

SENSORS (2020)

Article Engineering, Electrical & Electronic

Efficient Microchannel Cooling of Multiple Power Devices With Compact Flow Distribution for High Power-Density Converters

Remco van Erp et al.

IEEE TRANSACTIONS ON POWER ELECTRONICS (2020)

Article Chemistry, Analytical

Direct Current Electrokinetic Particle Trapping in Insulator-Based Microfluidics: Theory and Experiments

Braulio Cardenas-Benitez et al.

ANALYTICAL CHEMISTRY (2020)

Article Multidisciplinary Sciences

Co-designing electronics with microfluidics for more sustainable cooling

Remco van Erp et al.

NATURE (2020)

Review Chemistry, Analytical

Acoustic Microfluidic Separation Techniques and Bioapplications: A Review

Yuan Gao et al.

MICROMACHINES (2020)

Article Computer Science, Information Systems

Talk2Lab: The Smart Lab of the Future

Nicola J. Knight et al.

IEEE INTERNET OF THINGS JOURNAL (2020)

Article Biochemical Research Methods

On-chip analysis of atmospheric ice-nucleating particles in continuous flow

Mark D. Tarn et al.

LAB ON A CHIP (2020)

Article Biochemical Research Methods

Joule heating-induced particle manipulation on a microfluidic chip

Golak Kunti et al.

BIOMICROFLUIDICS (2019)

Article Computer Science, Interdisciplinary Applications

Artificial Neural Network control of thermoelectrically-cooled microfluidics using computer vision based on IR thermography

Benjamin A. Rizkin et al.

COMPUTERS & CHEMICAL ENGINEERING (2019)

Article Physics, Applied

Enhanced Cooling of Electronic Chips Using Combined Diamond Coating and Microfluidics

Dor Daniel et al.

PHYSICAL REVIEW APPLIED (2019)

Article Chemistry, Analytical

A wearable IoT aldehyde sensor for pediatric asthma research and management

Baichen Li et al.

SENSORS AND ACTUATORS B-CHEMICAL (2019)

Review Chemistry, Analytical

Advancement of electroosmotic pump in microflow analysis

Lin Li et al.

ANALYTICA CHIMICA ACTA (2019)

Article Biochemical Research Methods

Ultrafast, low-power, PCB manufacturable, continuous-flow microdevice for DNA amplification

Georgia D. Kaprou et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2019)

Article Engineering, Environmental

A Droplet Microfluidic-Based Sensor for Simultaneous in Situ Monitoring of Nitrate and Nitrite in Natural Waters

Adrian M. Nightingale et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2019)

Article Chemistry, Analytical

On-chip real-time monitoring of multiple displacement amplification of DNA

B. B. Bruijns et al.

SENSORS AND ACTUATORS B-CHEMICAL (2019)

Review Pharmacology & Pharmacy

Application of microfluidic chip technology in pharmaceutical analysis: A review

Ping Cui et al.

JOURNAL OF PHARMACEUTICAL ANALYSIS (2019)

Article Biophysics

Continuous flow production of size-controllable niosomes using a thermostatic microreactor

Pablo Garcia-Manrique et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2019)

Article Chemistry, Analytical

Temperature-Controlled Microfluidic System Incorporating Polymer Tubes

Jiu Yang Zhu et al.

ANALYTICAL CHEMISTRY (2019)

Review Chemistry, Analytical

AC Electrothermal Effect in Microfluidics: A Review

Alinaghi Salari et al.

MICROMACHINES (2019)

Article Chemistry, Analytical

Isolation and identification of Listeria monocytogenes utilizing DC insulator-based dielectrophoresis

Claire V. Crowther et al.

ANALYTICA CHIMICA ACTA (2019)

Article Multidisciplinary Sciences

Ten-Second Electrophysiology: Evaluation of the 3DEP Platform for high-speed, high-accuracy cell analysis

Kai F. Hoettges et al.

SCIENTIFIC REPORTS (2019)

Article Biochemical Research Methods

Luminescence thermometry for in situ temperature measurements in microfluidic devices

Robin G. Geitenbeek et al.

LAB ON A CHIP (2019)

Review Biochemical Research Methods

Microfluidics Based Point-of-Care Diagnostics

Chandra M. Pandey et al.

BIOTECHNOLOGY JOURNAL (2018)

Article Chemistry, Analytical

An Affordable and Portable Thermocycler for Real-Time PCR Made of 3D-Printed Parts and Off-the-Shelf Electronics

Roberto A. Mendoza-Gallegos et al.

ANALYTICAL CHEMISTRY (2018)

Article Physics, Applied

The role of electric field in microfluidic heating induced by standing surface acoustic waves

Tengfei Zheng et al.

APPLIED PHYSICS LETTERS (2018)

Article Engineering, Biomedical

Portable low-power thermal cycler with dual thin-film Pt heaters for a polymeric PCR chip

Sangdo Jeong et al.

BIOMEDICAL MICRODEVICES (2018)

Review Biophysics

Point-of-care microfluidic devices for pathogen detection

Behzad Nasseri et al.

BIOSENSORS & BIOELECTRONICS (2018)

Article Automation & Control Systems

Indirect Temperature Measurement and Control Method for Cell Culture Devices

Antti-Juhana Maki et al.

IEEE TRANSACTIONS ON AUTOMATION SCIENCE AND ENGINEERING (2018)

Article Engineering, Electrical & Electronic

Paper-based resistive heater with accurate closed-loop temperature control for microfluidics paper-based analytical devices

Saeed Atabakhsh et al.

MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS (2018)

Article Biochemistry & Molecular Biology

The temperature dependence of the helical twist of DNA

Franziska Kriegel et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Biochemical Research Methods

A Portable Microscale Cell Culture System with Indirect Temperature Control

Antti-Juhana Maki et al.

SLAS TECHNOLOGY (2018)

Article Nanoscience & Nanotechnology

Multistage Chemical Heating for Instrument-Free Biosensing

John P. Goertz et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

Article Engineering, Electrical & Electronic

Modeling, Simulation, and Implementation of Fast Settling Switched PI Controller for MOX Integrated Pt Microheater

Samarth Singh et al.

IEEE SENSORS JOURNAL (2018)

Article Biochemical Research Methods

Ultra-sensitive microfluidic wearable strain sensor for intraocular pressure monitoring

Sevda Agaoglu et al.

LAB ON A CHIP (2018)

Article Chemistry, Multidisciplinary

An On-Chip SiC MEMS Device with Integrated Heating, Sensing, and Microfluidic Cooling Systems

Toan Dinh et al.

ADVANCED MATERIALS INTERFACES (2018)

Article Biochemical Research Methods

Effects of electrothermal vortices on insulator-based dielectrophoresis for circulating tumor cell separation

Arian Aghilinejad et al.

ELECTROPHORESIS (2018)

Article Biochemical Research Methods

Joule heating induced stream broadening in free-flow zone electrophoresis

Debashis Dutta

ELECTROPHORESIS (2018)

Article Engineering, Electrical & Electronic

Design and experiment of a PDMS-based PCR chip with reusable heater of optimized electrode

Feng Cui et al.

MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS (2017)

Article Materials Science, Multidisciplinary

Infrared, transient thermal, and electrical properties of silver nanowire thin films for transparent heaters and energy-efficient coatings

Marco Bobinger et al.

PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE (2017)

Article Biochemical Research Methods

Temperature controlled tensiometry using droplet microfluidics

Doojin Lee et al.

LAB ON A CHIP (2017)

Article Chemistry, Multidisciplinary

Low voltage driven surface micro-flow by Joule heating

H. Wang et al.

RSC ADVANCES (2017)

Article Chemistry, Multidisciplinary

Tailoring the Aqueous Synthesis and Deposition of Copper Nanowires for Transparent Electrodes and Heaters

Marco Bobinger et al.

ADVANCED MATERIALS INTERFACES (2017)

Article Chemistry, Analytical

Joule Heating-Induced Dispersion in Open Microfluidic Electrophoretic Cytometry

Julea Vlassakis et al.

ANALYTICAL CHEMISTRY (2017)

Article Chemistry, Analytical

Use of Ice-Nucleating Proteins To Improve the Performance of Freeze-Thaw Valves in Microfluidic Devices

Joseph C. Gaiteri et al.

ANALYTICAL CHEMISTRY (2017)

Article Engineering, Electrical & Electronic

Miniaturized 3-D Solenoid-Type Micro-Heaters in Coordination With 3-D Microfluidics

Hao Bian et al.

JOURNAL OF MICROELECTROMECHANICAL SYSTEMS (2017)

Review Chemistry, Analytical

Review: Microbial analysis in dielectrophoretic microfluidic systems

Renny E. Fernandez et al.

ANALYTICA CHIMICA ACTA (2017)

Article Chemistry, Analytical

Effective Thermo-Capillary Mixing in Droplet Microfluidics Integrated with a Microwave Heater

Gurkan Yesiloz et al.

ANALYTICAL CHEMISTRY (2017)

Article Biochemical Research Methods

Dielectrophoretic behavior of PEGylated RNase A inside a microchannel with diamond-shaped insulating posts

Marco A. Mata-Gomez et al.

ELECTROPHORESIS (2016)

Article Chemistry, Analytical

Smart cup: A minimally-instrumented, smartphone-based point-of-care molecular diagnostic device

Shih-Chuan Liao et al.

SENSORS AND ACTUATORS B-CHEMICAL (2016)

Article Multidisciplinary Sciences

Instrument for Real-Time Digital Nucleic Acid Amplification on Custom Microfluidic Devices

David A. Selck et al.

PLOS ONE (2016)

Article Engineering, Electrical & Electronic

Characterization of an acoustically coupled multilayered microfluidic platform on SAW substrate using mixing phenomena

Rahul Kishor et al.

SENSORS AND ACTUATORS A-PHYSICAL (2015)

Proceedings Paper Thermodynamics

Influence of Joule Heating on MHD Peristaltic Flow of a Nanofluid with Compliant Walls

M. Gnaneswara Reddy et al.

INTERNATIONAL CONFERENCE ON COMPUTATIONAL HEAT AND MASS TRANSFER (ICCHMT) - 2015 (2015)

Article Biochemical Research Methods

Joule heating effects on particle immobilization in insulator-based dielectrophoretic devices

Roberto C. Gallo-Villanueva et al.

ELECTROPHORESIS (2014)

Article Biochemical Research Methods

Optimization of a microfluidic electrophoretic immunoassay using a Peltier cooler

Nikita Mukhitov et al.

JOURNAL OF CHROMATOGRAPHY A (2014)

Article Biochemical Research Methods

Continuous microcarrier-based cell culture in a benchtop microfluidic bioreactor

F. Abeille et al.

LAB ON A CHIP (2014)

Article Engineering, Biomedical

Analytical study of a microfludic DNA amplification chip using water cooling effect

Jyh Jian Chen et al.

BIOMEDICAL MICRODEVICES (2013)

Article Biochemical Research Methods

Microfluidic lab-on-a-chip derivatization for gaseous carbonyl analysis

Xiaobing Pang et al.

JOURNAL OF CHROMATOGRAPHY A (2013)

Article Engineering, Electrical & Electronic

A temperature control method for shortening thermal cycling time to achieve rapid polymerase chain reaction (PCR) in a disposable polymer microfluidic device

Minqiang Bu et al.

JOURNAL OF MICROMECHANICS AND MICROENGINEERING (2013)

Article Biochemical Research Methods

Microwave sensing and heating of individual droplets in microfluidic devices

Muhammed S. Boybay et al.

LAB ON A CHIP (2013)

Article Instruments & Instrumentation

An electric stimulation system for electrokinetic particle manipulation in microfluidic devices

M. S. Lopez-de la Fuente et al.

REVIEW OF SCIENTIFIC INSTRUMENTS (2013)

Article Engineering, Manufacturing

3-D Stacked Tier-Specific Microfluidic Cooling for Heterogeneous 3-D ICs

Yue Zhang et al.

IEEE TRANSACTIONS ON COMPONENTS PACKAGING AND MANUFACTURING TECHNOLOGY (2013)

Review Medicine, General & Internal

A Review of Heating and Temperature Control in Microfluidic Systems: Techniques and Applications

Vincent Miralles et al.

DIAGNOSTICS (2013)

Review Biochemical Research Methods

Thermal Denaturation Assays in Chemical Biology

Guillermo Senisterra et al.

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2012)

Review Biochemical Research Methods

Microfabrication technologies in dielectrophoresis applications-A review

Rodrigo Martinez-Duarte

ELECTROPHORESIS (2012)

Article Biochemical Research Methods

High sensitivity three-dimensional insulator-based dielectrophoresis

William A. Braff et al.

LAB ON A CHIP (2012)

Review Biochemical Research Methods

Dielectrophoresis in microfluidics technology

Barbaros Cetin et al.

ELECTROPHORESIS (2011)

Article Immunology

Robustness of a loop-mediated isothermal amplification reaction for diagnostic applications

Patrice Francois et al.

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY (2011)

Article Thermodynamics

A Review of Cooling in Microchannels

Jami F. Tullius et al.

HEAT TRANSFER ENGINEERING (2011)

Article Biochemical Research Methods

An optimal design method for preventing air bubbles in high-temperature microfluidic devices

Tsuyoshi Nakayama et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2010)

Article Automation & Control Systems

System Design and Modeling of a Time-Varying, Nonlinear Temperature Controller for Microfluidics

Govind V. Kaigala et al.

IEEE TRANSACTIONS ON CONTROL SYSTEMS TECHNOLOGY (2010)

Article Biochemical Research Methods

A portable device for temperature control along microchannels

Daniele Vigolo et al.

LAB ON A CHIP (2010)

Review Biochemical Research Methods

Microfluidic cell culture systems for drug research

Min-Hsien Wu et al.

LAB ON A CHIP (2010)

Article Thermodynamics

Adaptive Chip Cooling Using Electrowetting on Coplanar Control Electrodes

J. -T. Cheng et al.

NANOSCALE AND MICROSCALE THERMOPHYSICAL ENGINEERING (2010)

Article Instruments & Instrumentation

Surface plasmon based thermo-optic and temperature sensor for microfluidic thermometry

L. J. Davis et al.

REVIEW OF SCIENTIFIC INSTRUMENTS (2010)

Article Engineering, Chemical

HEATING UNIFORMITY AND RATES IN A DOMESTIC MICROWAVE COMBINATION OVEN

V. Rakesh et al.

JOURNAL OF FOOD PROCESS ENGINEERING (2009)

Review Biochemical Research Methods

Joule heating in electrokinetic flow

Xiangchun Xuan

ELECTROPHORESIS (2008)

Article Chemistry, Analytical

Enhancement of thermal uniformity for a microthermal cycler and its application for polymerase chain reaction

Tsung-Min Hsieh et al.

SENSORS AND ACTUATORS B-CHEMICAL (2008)

Article Engineering, Electrical & Electronic

Simulation and experimental validation of a SU-8 based PCR thermocycler chip with integrated heaters and temperature sensor

J El-Ali et al.

SENSORS AND ACTUATORS A-PHYSICAL (2004)

Article Biochemical Research Methods

Precise temperature control in microfluidic devices using Joule heating of ionic liquids

AJ de Mello et al.

LAB ON A CHIP (2004)

Article Biochemical Research Methods

Chemical and physical processes for integrated temperature control in microfluidic devices

RM Guijt et al.

LAB ON A CHIP (2003)

Article Biochemical Research Methods

Joule heating and heat transfer in poly(dimethylsiloxane) microfluidic systems

D Erickson et al.

LAB ON A CHIP (2003)

Review Chemistry, Multidisciplinary

Poly(dimethylsiloxane) as a material for fabricating microfluidic devices

JC McDonald et al.

ACCOUNTS OF CHEMICAL RESEARCH (2002)

Article Chemistry, Multidisciplinary

A microfluidic device with a linear temperature gradient for parallel and combinatorial measurements

HB Mao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)