Electrochemical Synthesis of Shape-controlled Cu-Ni Nanocomposite and its Application for Nonenzymatic Glucose Sensing at Nanomolar Level

The electrodeposition method was firstly applied to obtain uniform cube-shaped copper nanoparticles on conductive glass (ITO), and then a layer of tiny nickel nanoparticles. A bimetallic composite electrode (Cu-Ni/ITO), characterized by TEM, XPS and XRD, was prepared to construct the non-enzyme electrochemical glucose sensor with high catalytic activity. The catalytic performance of Cu-Ni/ITO had been greatly improved, probably due to the synergistic bimetallic catalysis effect. The electrode had a satisfactory linear response in the range of 2.5x10(-7) M to 2.6x10(-3) M, with detection limit as low as 67 nM. Besides, Cu-Ni/ITO had good anti-interference ability and reproducibility, indicating the promising application for glucose detection in practical samples.

Automated summary

Uniform cube-shaped copper nanoparticles and tiny nickel nanoparticles were obtained using the electrodeposition method, leading to the construction of a non-enzyme electrochemical glucose sensor with high catalytic activity. The bimetallic composite electrode showed improved catalytic performance due to the synergistic bimetallic catalysis effect. The electrode exhibited satisfactory linear response, low detection limit, good anti-interference ability, and reproducibility for glucose detection in practical samples.