期刊
DIGESTIVE DISEASES AND SCIENCES
卷 68, 期 4, 页码 1125-1138出版社
SPRINGER
DOI: 10.1007/s10620-022-07672-9
关键词
Laryngopharyngeal reflux; Gastroesophageal reflux; Delphi
Best practice statements for the treatment of LPR were identified using a well-tested methodology. These statements serve as a guide for physicians in making treatment decisions for LPR.
Background Laryngopharyngeal reflux (LPR) is a common otolaryngologic diagnosis. Treatment of presumed LPR remains challenging, and limited frameworks exist to guide treatment. Methods Using RAND/University of California, Los Angeles (UCLA) Appropriateness Methods, a modified Delphi approach identified consensus statements to guide LPR treatment. Experts independently and blindly scored proposed statements on importance, scientific acceptability, usability, and feasibility in a four-round iterative process. Accepted measures reached scores with >= 80% agreement in the 7-9 range (on a 9-point Likert scale) across all four categories. Results Fifteen experts rated 36 proposed initial statements. In round one, 10 (27.8%) statements were rated as valid. In round two, 8 statements were modified based on panel suggestions, and experts subsequently rated 5 of these statements as valid. Round three's discussion refined statements not yet accepted, and in round four, additional voting identified 2 additional statements as valid. In total, 17 (47.2%) best practice statements reached consensus, touching on topics as varied as role of empiric treatment, medication use, lifestyle modifications, and indications for laryngoscopy. Conclusion Using a well-tested methodology, best practice statements in the treatment of LPR were identified. The statements serve to guide physicians on LPR treatment considerations.
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