4.3 Article

Design, Synthesis, Molecular Docking, ADMET, and Biological Studies of Some Novel 1,2,3-Triazole Linked Tetrazoles as Anticancer Agents

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Chemistry, Medicinal

1,2,3-Triazole hybrids with anti-HIV-1 activity

Lian-Shun Feng et al.

Summary: This review focuses on the recent advances in 1,2,3-triazole hybrids with potential anti-HIV-1 activity, covering chemical structures, mechanisms of action, and structure-activity relationships from articles published between 2010 and 2020.

ARCHIV DER PHARMAZIE (2021)

Article Multidisciplinary Sciences

The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors

Teklab Gebregiworgis et al.

Summary: This study demonstrates that KRAS Q61H mutation is not regulated by SHP2, leading to insensitivity to SHP2 inhibitors in pancreatic cancer cells. Furthermore, cancer cells with different KRAS mutations exhibit variable sensitivity to SHP2 inhibitors, potentially due to differences in regulation by GAP and GEF activities, as well as binding affinity to RAF.

NATURE COMMUNICATIONS (2021)

Review Chemistry, Multidisciplinary

Tetrazoles via Multicomponent Reactions

Constantinos G. Neochoritis et al.

CHEMICAL REVIEWS (2019)

Review Chemistry, Medicinal

Triazole derivatives and their antiplasmodial and antimalarial activities

Xue-Mei Chu et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)

Review Oncology

New Horizons in KRAS-Mutant Lung Cancer: Dawn After Darkness

Haitang Yang et al.

FRONTIERS IN ONCOLOGY (2019)

Article Biochemistry & Molecular Biology

Design, synthesis and antibacterial activity evaluation of moxifloxacin-amide-1,2,3-triazole-isatin hybrids

Feng Gao et al.

BIOORGANIC CHEMISTRY (2019)

Review Chemistry, Medicinal

Current scenario of tetrazole hybrids for antibacterial activity

Feng Gao et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)

Article Biochemistry & Molecular Biology

PDBsum: Structural summaries of PDB entries

Roman A. Laskowski et al.

PROTEIN SCIENCE (2018)

Article Chemistry, Multidisciplinary

Synthesis and Antimalarial Evaluation of [1,2,3]-Triazole-Tethered Sulfonamide-Berberine Hybrids

Neha Batra et al.

CHEMISTRYSELECT (2018)

Review Multidisciplinary Sciences

The biology and management of non-small cell lung cancer

Roy S. Herbst et al.

NATURE (2018)

Article Microbiology

Triazole Substitution of a Labile Amide Bond Stabilizes Pantothenamides and Improves Their Antiplasmodial Potency

Vanessa M. Howieson et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)

Article Biochemistry & Molecular Biology

Synthesis of novel tetrazole derivatives and evaluation of their antifungal activity

Edyta Lukowska-Chojnacka et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2016)

Article Multidisciplinary Sciences

Genomic analyses identify molecular subtypes of pancreatic cancer

Peter Bailey et al.

NATURE (2016)

Review Chemistry, Medicinal

Imidazothiazole and related heterocyclic systems. Synthesis, chemical and biological properties

Mirta L. Fascio et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)

Review Biochemistry & Molecular Biology

Tetrazolium Compounds: Synthesis and Applications in Medicine

Cheng-Xi Wei et al.

MOLECULES (2015)

Article Chemistry, Organic

New click-chemistry methods for 1,2,3-triazoles synthesis: recent advances and applications

Jane Totobenazara et al.

TETRAHEDRON LETTERS (2015)

Article Chemistry, Medicinal

New class of methyl tetrazole based hybrid of (Z)-5-benzylidene-2-(piperazin-1-yl)thiazol-4(%H)-one as potent antitubercular agents

Kuldeep Chauhan et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)

Article Chemistry, Organic

Synthesis of Tetrazole-Derived Organocatalysts via Azido-Ugi Reaction with Cyclic Ketimines

Olga I. Shmatova et al.

JOURNAL OF ORGANIC CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

Synthesis and anti-HSV-1 activity of new 1,2,3-triazole derivatives

Alessandro K. Jordao et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2011)

Article Chemistry, Applied

Diversity-Oriented Synthesis of Quinolines via Friedlander Annulation Reaction under Mild Catalytic Conditions

D. Subhas Bose et al.

JOURNAL OF COMBINATORIAL CHEMISTRY (2010)

Review Chemistry, Organic

Biological Importance of the Indole Nucleus in Recent Years: A Comprehensive Review

Vikas Sharma et al.

JOURNAL OF HETEROCYCLIC CHEMISTRY (2010)

Article Chemistry, Multidisciplinary

AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility

Garrett M. Morris et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)

Review Chemistry, Medicinal

Sulfanyltriazole/tetrazoles: A Promising Class of HIV-1 NNRTIs

Peng Zhan et al.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2009)

Article Chemistry, Medicinal

Synthesis of novel substituted tetrazoles having antifungal activity

RS Upadhayaya et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2004)

Article Chemistry, Multidisciplinary

Rate-limited steps of human oral absorption and QSAR studies

YH Zhao et al.

PHARMACEUTICAL RESEARCH (2002)