相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Glycoconjugated Metal Complexes as Cancer Diagnostic and Therapeutic Agents
Giulia Bononi et al.
CHEMMEDCHEM (2021)
Interaction with Ribosomal Proteins Accompanies Stress Induction of the Anticancer Metallodrug BOLD-100/KP1339 in the Endoplasmic Reticulum
Benjamin Neuditschko et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)
Beyond Osimertinib: The Development of Third-Generation EGFR Tyrosine Kinase Inhibitors For Advanced EGFR plus NSCLC
Misako Nagasaka et al.
JOURNAL OF THORACIC ONCOLOGY (2021)
Mechanisms and management of 3rd-generation EGFR-TKI resistance in advanced non-small cell lung cancer (Review)
Jingyi He et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2021)
Development of a cobalt(III)-based ponatinib prodrug system
Marlene Mathuber et al.
INORGANIC CHEMISTRY FRONTIERS (2021)
Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC
S. S. Ramalingam et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Experience with ponatinib in paediatric patients with leukaemia
Jenna Rossoff et al.
BRITISH JOURNAL OF HAEMATOLOGY (2020)
Co-delivery of erlotinib and doxorubicin by MoS2 nanosheets for synergetic photothermal chemotherapy of cancer
Jian Liu et al.
CHEMICAL ENGINEERING JOURNAL (2020)
An Erlotinib gold(I) conjugate for combating triple-negative breast cancer
Enrique Ortega et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2020)
Applying Quality by Design Principles in the Development and Preparation of a New Radiopharmaceutical: Technetium-99m-Imatinib Mesylate
Evren Gundogdu et al.
ACS OMEGA (2020)
Synthesis, characterization and evaluation of 68 Ga labelled monomeric and dimeric quinazoline derivatives of the HBED-CC chelator targeting the epidermal growth factor receptor
Christos Liolios et al.
BIOORGANIC CHEMISTRY (2020)
Inhibition of histone deacetylases, topoisomerases and epidermal growth factor receptor by metal-based anticancer agents: Design & synthetic strategies and their medicinal attributes
Manpreet Kaur et al.
BIOORGANIC CHEMISTRY (2020)
Improving the Stability of EGFR Inhibitor Cobalt(III) Prodrugs
Marlene Mathuber et al.
INORGANIC CHEMISTRY (2020)
VEGFR2 promotes tumorigenesis and metastasis in a pro-angiogenic-independent way in gastric cancer
Lian Lian et al.
BMC CANCER (2019)
Tyrosine Kinase Inhibitor Gold Nanoconjugates for the Treatment of Non-Small Cell Lung Cancer
Alexander M. Cryer et al.
ACS APPLIED MATERIALS & INTERFACES (2019)
A Novel Conjugate of Bis[((4-bromophenyl)amino)quinazoline], a EGFR-TK Ligand, with a Fluorescent Ru(II)-Bipyridine Complex Exhibits Specific Subcellular Localization in Mitochondria
Rashid Ilmi et al.
MOLECULAR PHARMACEUTICS (2019)
Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433
Susan Monro et al.
CHEMICAL REVIEWS (2019)
Nanoparticle co-delivery of wortmannin and cisplatin synergistically enhances chemoradiotherapy and reverses platinum resistance in ovarian cancer models
Maofan Zhang et al.
BIOMATERIALS (2018)
Photoactivation of imatinib-antibody conjugate using low-energy visible light from Ru(II)-polypyridyl cages
Thomas N. Rohrabaugh et al.
CHEMICAL COMMUNICATIONS (2018)
Platination of cysteine by an epidermal growth factor receptor kinase-targeted hybrid agent
Mu Yang et al.
CHEMICAL COMMUNICATIONS (2018)
The role of small molecule platelet-derived growth factor receptor (PDGFR) inhibitors in the treatment of neoplastic disorders
Robert Roskoski
PHARMACOLOGICAL RESEARCH (2018)
Structural insights into drug development strategy targeting EGFR T790M/C797S
Su-Jie Zhu et al.
Oncotarget (2018)
Luminescent cyclometallated platinum(II) complexes: highly promising EGFR/DNA probes and dual-targeting anticancer agents
Yang Zhang et al.
INORGANIC CHEMISTRY FRONTIERS (2018)
Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety
Supojjanee Sansook et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2017)
Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways
Ping Wee et al.
CANCERS (2017)
Combination of ruthenium(II)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) and the epidermal growth factor receptor inhibitor erlotinib results in efficient angiostatic and antitumor activity
Robert H. Berndsen et al.
SCIENTIFIC REPORTS (2017)
68Ga labeled Erlotinib: A novel PET probe for imaging EGFR over-expressing tumors
Akanksha Jain et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
Carbohydrate-N-heterocyclic carbene metal complexes: Synthesis, catalysis and biological studies
Weihao Zhao et al.
COORDINATION CHEMISTRY REVIEWS (2017)
Recent progress on third generation covalent EGFR inhibitors
Hengmiao Cheng et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Organometallic-Peptide Bioconjugates: Synthetic Strategies and Medicinal Applications
Bauke Albada et al.
CHEMICAL REVIEWS (2016)
FDA Approval of Gefitinib for the Treatment of Patients with Metastatic EGFR Mutation-Positive Non-Small Cell Lung Cancer
Dickran Kazandjian et al.
CLINICAL CANCER RESEARCH (2016)
Synthesis, Characterization, and in Vitro Antitumor Activity of Ruthenium(II) Polypyridyl Complexes Tethering EGFR-Inhibiting 4-Anilinoquinazolines
Jun Du et al.
INORGANIC CHEMISTRY (2016)
Antioxidant, DNA interaction, VEGFR2 kinase, topoisomerase I and in vitro cytotoxic activities of heteroleptic copper(II) complexes of tetrazolo[1,5-a]pyrimidines and diimines
A. Haleel et al.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2016)
Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells
Maryam Abbaspour Babaei et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2016)
Safety and activity of IT-139, a ruthenium-based compound, in patients with advanced solid tumours: a first-in- human, open-label, dose-escalation phase I study with expansion cohort
Howard A. Burris et al.
ESMO OPEN (2016)
Dual-targeting organometallic ruthenium(II) anticancer complexes bearing EGFR-inhibiting 4-anilinoquinazoline ligands
Yang Zhang et al.
DALTON TRANSACTIONS (2015)
Synthesis, Reactivity, and Biological Activity of Gold(I) Complexes Modified with Thiourea-Functionalized Tyrosine Kinase Inhibitors
Mu Yang et al.
INORGANIC CHEMISTRY (2015)
Synergistic cytotoxicity from combination of imatinib and platinum-based anticancer drugs specifically in Bcr-Abl positive leukemia cells
Yuming Wei et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2015)
Discovery of a dual-targeting organometallic ruthenium complex with high activity inducing early stage apoptosis of cancer cells
Jun Du et al.
METALLOMICS (2015)
FDA-approved small-molecule kinase inhibitors
Peng Wu et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2015)
Molecular-Target-Based Anticancer Photosensitizer: Synthesis and in vitro Photodynamic Activity of Erlotinib-Zinc(II) Phthalocyanine Conjugates
Feng-Ling Zhang et al.
CHEMMEDCHEM (2015)
Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy
Suzanne Leijen et al.
INVESTIGATIONAL NEW DRUGS (2015)
Tumor-Targeting of EGFR Inhibitors by Hypoxia-Mediated Activation
Claudia Karnthaler-Benbakka et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Targeted Chemotherapy with Metal Complexes
Alyson G. Weidmann et al.
COMMENTS ON INORGANIC CHEMISTRY (2014)
Metal complexes as structural templates for targeting proteins
Markus Doerr et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2014)
Novel ruthenium complexes ligated with 4-anilinoquinazoline derivatives: Synthesis, characterisation and preliminary evaluation of biological activity
Liyun Ji et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Copper Phenanthrene Oxidative Chemical Nucleases
Zara Molphy et al.
INORGANIC CHEMISTRY (2014)
Adsorption and desorption of tyrosine kinase inhibitor erlotinib on gold nanoparticles
Anh Thu Ngoc Lam et al.
JOURNAL OF COLLOID AND INTERFACE SCIENCE (2014)
A Tyrosine Kinase Inhibitor-Based High-Affinity PET Radiopharmaceutical Targets Vascular Endothelial Growth Factor Receptor
Feng Li et al.
JOURNAL OF NUCLEAR MEDICINE (2014)
Complexation with organometallic ruthenium pharmacophores enhances the ability of 4-anilinoquinazolines inducing apoptosis
Wei Zheng et al.
CHEMICAL COMMUNICATIONS (2013)
A novel strategy for targeting photodynamic therapy. Molecular combo of photodynamic agent zinc(II) phthalocyanine and small molecule target-based anticancer drug erlotinib
Feng-Ling Zhang et al.
CHEMICAL COMMUNICATIONS (2013)
Targeting Epidermal Growth Factor Receptor with Ferrocene-Based Kinase Inhibitors
Jahangir Amin et al.
ORGANOMETALLICS (2013)
Synthesis of Oxindole-Based Bioorganometallic Kinase Inhibitors Incorporating One or More Ferrocene Groups
Jahangir Amin et al.
ORGANOMETALLICS (2013)
Blockade of the PDGFR family together with SRC leads to diminished proliferation of colorectal cancer cells
Silke Kaulfuss et al.
ONCOTARGET (2013)
Phase I study of imatinib, cisplatin and 5-fluoruracil or capecitabine in advanced esophageal and gastric adenocarcinoma
Martina Mayr et al.
BMC CANCER (2012)
Imatinib-ULS-lysozyme: A proximal tubular cell-targeted conjugate of imatinib for the treatment of renal diseases
M. E. M. Dolman et al.
JOURNAL OF CONTROLLED RELEASE (2012)
Development of a Cell-Selective and Intrinsically Active Multikinase Inhibitor Bioconjugate
Stefan Harmsen et al.
BIOCONJUGATE CHEMISTRY (2011)
Multicenter Independent Assessment of Outcomes in Chronic Myeloid Leukemia Patients Treated With Imatinib
Carlo Gambacorti-Passerini et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2011)
Synthesis and evaluation of metallocene containing methylidene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors
John Spencer et al.
METALLOMICS (2011)
Size Does Matter. Sterically Demanding Metallocene-Substituted 3-Methylidene-Oxindoles Exhibit Poor Kinase Inhibitory Action
John Spencer et al.
ORGANOMETALLICS (2011)
Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects
Ana-Maria Florea et al.
Cancers (2011)
Oncogenic mutant forms of EGFR: Lessons in signal transduction and targets for cancer therapy
Gur Pines et al.
FEBS LETTERS (2010)
Organ- and Cell-Type Specific Delivery of Kinase Inhibitors: A Novel Approach in the Development of Targeted Drugs
Robbert Kok et al.
Current Molecular Pharmacology (2010)
The antimicrobial properties of copper surfaces against a range of important nosocomial pathogens
Simon W. J. Gould et al.
ANNALS OF MICROBIOLOGY (2009)
Positron Emission Tomography (PET) Imaging with [11C]-Labeled Erlotinib: A Micro-PET Study on Mice with Lung Tumor Xenografts
Ashfaque A. Memon et al.
CANCER RESEARCH (2009)
Mononuclear six-coordinated Ga(III) complexes: A comprehensive survey
Giuliano Bandoli et al.
COORDINATION CHEMISTRY REVIEWS (2009)
Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones
John Spencer et al.
DALTON TRANSACTIONS (2009)
Synthesis and characterization of rhenium and technetium-99m tricarbonyl complexes bearing the 4-[3-bromophenyl]quinazoline moiety as a biomarker for EGFR-TK imaging
Athanasia Bourkoula et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2009)
A quinazoline-derivative DOTA-type gallium(III) complex for targeting epidermal growth factor receptors: synthesis, characterisation and biological studies
Raquel Garcia et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2009)
KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients
Christian G. Hartinger et al.
CHEMISTRY & BIODIVERSITY (2008)
Synthesis of ferrocenyl oxindole compounds with potential anticancer activity
Barbara V. Silva et al.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY (2008)
Synthesis of ferrocenyl monospirooxindolopyrrolidines-a facile [3+2]-cycloaddition of azomethine ylides
A. R. Suresh Babu et al.
TETRAHEDRON LETTERS (2008)
Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance
Hagop M. Kantarjian et al.
BLOOD (2007)
Synergistic and additive antiproliferative effects on human leukemia cell lines induced by combining acetylenehexacarbonyldicobalt complexes with the tyrosine kinase inhibitor imatinib
Ingo Ott et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2006)
Molecular imaging of EGFR kinase activity in tumors with 124I-labeled small molecular tracer and positron emission tomography
A. Pal et al.
MOLECULAR IMAGING AND BIOLOGY (2006)
Synthesis of [11C]Iressa as a new potential PET cancer imaging agent for epidermal growth factor receptor tyrosine kinase
Ji-Quan Wang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL
Hagop Kantarjian et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Fluoriue-18 labeling of 6,7-disubstituted anilinoquinazoline derivatives for positron emission tomography (PET) imaging of tyrosine kinase receptors:: synthesis of 18F-Iressa and related molecular probes
Y Seimbille et al.
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS (2005)
Cisplatin-evoked DNA fragmentation in normal and cancer cells and its modulation by free radical scavengers and the tyrosine kinase inhibitor STI571
K Wozniak et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2004)
Preclinical characterisation of 111In-DTPA-trastuzumab
MN Lub-de Hooge et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Kinetics of aquation and anation of Ruthenium(II) arene anticancer complexes, acidity and X-ray structures of aqua adducts
F Wang et al.
CHEMISTRY-A EUROPEAN JOURNAL (2003)
A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-γ and DNA synthesis in vascular endothelial cells
T Takahashi et al.
EMBO JOURNAL (2001)
Influence of the denticity of ligand systems on the in vitro and in vivo behavior of 99mTc(I)-tricarbonyl complexes:: A hint for the future functionalization of biomolecules
R Schibli et al.
BIOCONJUGATE CHEMISTRY (2000)
分享论文
