期刊
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
卷 226, 期 -, 页码 -出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.cmpb.2022.107114
关键词
X-ray coronary angiography; Centerline extraction; C-UNet; Centerline reconnection
类别
资金
- National Key R&D Program of China [2021YFA1000202]
- National Natural Science Foundation of China [61972227]
- Natural Science Foundation of Shandong Province [ZR2019MF051, ZR2018 08160102]
- project of Independent Cultivated Innovation Team of Jinan City [2020GXRC016]
- Fostering Project of Dominant Discipline and Talent Team of Shandong Province Higher Education Institutions
In this study, a centerline extraction method based on deep learning and conventional methods is proposed, which can automatically and accurately extract vascular centerlines from X-ray coronary angiography images.
Background and objective: Accurate extraction of the coronary artery centerline is crucial in the processes of coronary artery reconstruction, coronary artery stenosis or lesion detection, and surgical navigation. Furthermore, in clinical medicine, the complex background of angiography, low signal-to-noise ratio, and complex vascular structure make coronary artery centerline extraction challenging. In this study, a direct centerline extraction method is proposed that automatically and accurately extracts vascular centerlines from X-ray coronary angiography images based on deep learning and conventional methods.Methods: In this study, a coronary artery centerline extraction method is proposed that comprises two parts: the preliminary centerline extraction network based on U-Net with a residual network, called C-UNet, and the multifactor centerline reconnection algorithm based on the geometric characteristics of blood vessels.Results: The qualitative and quantitative results demonstrate the effectiveness of the presented method. In this study, three widely used evaluation indices were adopted to evaluate the performance of the method: precision, recall, and F1 _Score. The experimental results show that this method can accurately extract coronary artery centerlines.Conclusions: The proposed centerline extraction method accurately extracts centerlines from X-ray coro-nary angiography images and improves both the accuracy and continuity of centerline extraction.(c) 2022 Elsevier B.V. All rights reserved.
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