Programmable, biodegradable composite scaffolds with variable pore morphology for minimal invasive bone repair

Article Materials Science, Biomaterials

Shape-memory materials and their clinical applications

Raana Sarvari et al.

Summary: Shape-memory materials offer unconventional functions in materials science and have significant potential for biomedical applications. However, their long-term biocompatibility for permanent applications remains a critical issue.

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS (2022)

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Review Chemistry, Multidisciplinary

A Review of Shape Memory Polymers and Composites: Mechanisms, Materials, and Applications

Yuliang Xia et al.

Summary: SMPs and SMPCs, as stimuli-responsive polymers, have broad application prospects in multiple fields with features of large recoverable deformation, enhanced mechanical properties, and controllable remote actuation. These materials combine functional, reversible, multiple, and controllable shape recovery processes, applicable in aerospace engineering, biomedical devices, flexible electronics, and soft robotics among others.

ADVANCED MATERIALS (2021)

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Review Materials Science, Biomaterials

Recent advances in tissue engineering scaffolds based on polyurethane and modified polyurethane

Bushra Naureen et al.

Summary: Polyurethane is a high-performance medical grade synthetic polymer that has gained significant attention in tissue engineering due to its unique properties. Modified polyurethane scaffolds have been widely used in both soft and hard tissue engineering, providing new avenues for tissue repair, regeneration, and transplantation.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

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Article Polymer Science

Facile preparation of light-weight biodegradable and electrically conductive polymer based nanocomposites for superior electromagnetic interference shielding effectiveness

Krishnendu Nath et al.

Summary: The study focused on the development of biodegradable EMI shielding polymer nanocomposites using conducting carbon black and a blend of polylactic acid and thermoplastic polyurethane, which showed excellent mechanical properties and improved thermal performance. The polymer nanocomposites demonstrated good EMI shielding effectiveness at X-band frequencies and satisfactory biodegradability through respirometry analysis.

JOURNAL OF APPLIED POLYMER SCIENCE (2021)

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Article Materials Science, Composites

Porous bone tissue scaffold concept based on shape memory PLA/Fe3O4

Wei Zhao et al.

Summary: Bone tissue engineering involves the development of 3D printed porous scaffolds based on shape memory polymer composite (SMPC), which are designed with the addition of magnetic nanoparticles for perfect matching when implanted in the body. The designs are inspired by thorough observation and analysis of lotus root structures, with experiments demonstrating the reliability and biological activity of the scaffolds.

COMPOSITES SCIENCE AND TECHNOLOGY (2021)

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Article Materials Science, Biomaterials

Gelatin-polycaprolactone-nanohydroxyapatite electrospun nanocomposite scaffold for bone tissue engineering

Sneh Gautam et al.

Summary: The electrospun Gelatin-PCL-nHAp nanocomposite scaffold showed promising results for bone tissue engineering applications, with good viability and proliferation of human osteoblasts. Analysis also indicated efficient cellular attachment and characteristic polygonal morphology of osteoblasts on the scaffold surface, demonstrating its potential for BTE.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

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Review Engineering, Biomedical

Biobased polyurethanes for biomedical applications

Sophie Wendels et al.

Summary: Polyurethanes (PUs) have a wide range of applications in the biomedical field, showing advanced properties such as controlled biotic and abiotic degradation. They possess precise tissue biomimicking structures and shape-recovery properties, making them suitable for cell adhesion, proliferation, and differentiation. While substitution of fossil-based materials for biomedical implants is slowly improving, achieving higher renewable contents is still necessary for biobased certifications.

BIOACTIVE MATERIALS (2021)

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Article Chemistry, Multidisciplinary

Biomimetic scaffolds with programmable pore structures for minimum invasive bone repair

Li Wang et al.

Summary: A series of biomimetic hydroxyapatite/shape-memory composite scaffolds with programmable pore structures were designed and synthesized, showing potential application promise in bone regeneration.

NANOSCALE (2021)

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Article Materials Science, Biomaterials

A 3D printed Ga containing scaffold with both anti-infection and bone homeostasis-regulating properties for the treatment of infected bone defects

Minqi Wang et al.

Summary: The study created a dual-functional scaffold with anti-infection and bone-homeostasis-regulating capacities, which demonstrated excellent antibacterial ability and promotion of bone healing both in vitro and in vivo.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

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Article Materials Science, Biomaterials

Smart scaffolds: shape memory polymers (SMPs) in tissue engineering

Michaela R. Pfau et al.

Summary: Smart scaffolds based on shape memory polymers have great potential in tissue engineering for regenerating bone, cartilage, and cardiovascular tissues. These scaffolds utilize unique shape memory abilities to improve drug delivery and tissue defect filling, and can be thermoresponsive or hydroresponsive.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

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Article Materials Science, Biomaterials

Engineering 3D-printed core-shell hydrogel scaffolds reinforced with hybrid hydroxyapatite/polycaprolactone nanoparticles for in vivo bone regeneration

Salma E. El-Habashy et al.

Summary: This study utilized 3D printing to fabricate a bone-conductive composite biological scaffold, reinforced with hybrid bioactive hydroxyapatite/polycaprolactone nanoparticles, demonstrating controlled swelling and structural integrity maintenance.

BIOMATERIALS SCIENCE (2021)

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Article Chemistry, Multidisciplinary

Facile scalable one-step wet-spinning of surgical sutures with shape memory function and antibacterial activity for wound healing

Xinghan Chen et al.

CHINESE CHEMICAL LETTERS (2020)

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Review Materials Science, Biomaterials

Recent trends in the application of widely used natural and synthetic polymer nanocomposites in bone tissue regeneration

Angshuman Bharadwaz et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

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Article Materials Science, Composites

Bio-based composites from plant based precursors and hydroxyapatite with shape-memory capability

Tuck-Whye Wong et al.

COMPOSITES SCIENCE AND TECHNOLOGY (2020)

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Review Nanoscience & Nanotechnology

Materials design for bone-tissue engineering

Gerry L. Koons et al.

NATURE REVIEWS MATERIALS (2020)

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Article Materials Science, Multidisciplinary

Porous 3D hydroxyapatite/polyurethane composite scaffold for bone tissue engineering and itsin vitrodegradation behavior

Kun Luo et al.

FERROELECTRICS (2020)

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Review Engineering, Biomedical

3D printing of bone tissue engineering scaffolds

Chong Wang et al.

BIOACTIVE MATERIALS (2020)

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Article Polymer Science

3D printing of shape memory poly(d,l-lactide-co-trimethylene carbonate) by direct ink writing for shape-changing structures

Xue Wan et al.

JOURNAL OF APPLIED POLYMER SCIENCE (2019)

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Review Engineering, Biomedical

Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review

Sugandha Chahal et al.

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2019)

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Review Materials Science, Biomaterials

Advances in additive manufacturing for bone tissue engineering scaffolds

Ana Paula Moreno Madrid et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

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Article Materials Science, Composites

Assessment of osteogenesis for 3D-printed polycaprolactone/hydroxyapatite composite scaffold with enhanced exposure of hydroxyapatite using rat calvarial defect model

Yong Sang Cho et al.

COMPOSITES SCIENCE AND TECHNOLOGY (2019)

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Article Materials Science, Multidisciplinary

Influence of pore size and hydroxyapatite deposition in poly(L-lactide-co-glycolide) scaffolds on osteoblast-like cells cultured in static and dynamic conditions

Malgorzata Krok-Borkowicz et al.

MATERIALS LETTERS (2019)

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Review Materials Science, Biomaterials

A review of emerging bone tissue engineering via PEG conjugated biodegradable amphiphilic copolymers

Jiang-Ze Wang et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

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Review Polymer Science

Polymeric composites for powder-based additive manufacturing: Materials and applications

Shangqin Yuan et al.

PROGRESS IN POLYMER SCIENCE (2019)

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Review Chemistry, Multidisciplinary

Biomaterials for bone tissue engineering scaffolds: a review

Huawei Qu et al.

RSC ADVANCES (2019)

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Article Chemistry, Multidisciplinary

Fabrication of Light-Triggered Soft Artificial Muscles via a Mixed-Matrix Membrane Strategy

Qi Yu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

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Review Polymer Science

Recent Progress in Shape Memory Polymers for Biomedical Applications

Hong-Mei Chen et al.

CHINESE JOURNAL OF POLYMER SCIENCE (2018)

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Article Materials Science, Composites

Shape memory polymers for composites

Tong Mu et al.

COMPOSITES SCIENCE AND TECHNOLOGY (2018)

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Review Biochemistry & Molecular Biology

A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue Engineering

Deval Prasad Bhattarai et al.

MEMBRANES (2018)

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Review Materials Science, Biomaterials

Effect of microporosity on scaffolds for bone tissue engineering

Ke Zhang et al.

REGENERATIVE BIOMATERIALS (2018)

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Review Cell & Tissue Engineering

Bone biomaterials and interactions with stem cells

Chengde Gao et al.

BONE RESEARCH (2017)

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Review Nanoscience & Nanotechnology

Recent Advances in Shape Memory Soft Materials for Biomedical Applications

Benjamin Qi Yu Chan et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

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Article Pediatrics

Advances in tissue engineering

Robert Langer et al.

JOURNAL OF PEDIATRIC SURGERY (2016)

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Article Materials Science, Multidisciplinary

Preparation and cell infiltration of lotus-type porous nano-hydroxyapatite/polyurethane scaffold for bone tissue regeneration

Limei Li et al.

MATERIALS LETTERS (2015)

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Review Materials Science, Biomaterials

A review: Fabrication of porous polyurethane scaffolds

H. Janik et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2015)

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Review Materials Science, Multidisciplinary

Shape-memory polymers and their composites: Stimulus methods and applications

Jinsong Leng et al.

PROGRESS IN MATERIALS SCIENCE (2011)

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Article Materials Science, Composites

Properties and mechanism of two-way shape memory polyurethane composites

Shaojun Chen et al.

COMPOSITES SCIENCE AND TECHNOLOGY (2010)

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Article Polymer Science

Characterization of biodegradable and cytocompatible nano-hydroxyapatite/polycaprolactone porous scaffolds in degradation in vitro

Yuanyuan Wang et al.

POLYMER DEGRADATION AND STABILITY (2010)

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Review Polymer Science

Polymeric materials for bone and cartilage repair

D. Puppi et al.

PROGRESS IN POLYMER SCIENCE (2010)

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Article Chemistry, Physical

Degradation and biocompatibility of porous nano-hydroxyapatite/polyurethane composite scaffold for bone tissue engineering

Zhihong Dong et al.

APPLIED SURFACE SCIENCE (2009)

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Review Materials Science, Multidisciplinary

Bone structure and formation: A new perspective

Matthew J. Olszta et al.

MATERIALS SCIENCE & ENGINEERING R-REPORTS (2007)

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Review Polymer Science

Biodegradable polymers as biomaterials

Lakshmi S. Nair et al.

PROGRESS IN POLYMER SCIENCE (2007)

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Review Cell & Tissue Engineering

State of the art and future directions of scaffold-based bone engineering from a biomaterials perspective

Dietmar Werner Hutmacher et al.

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2007)

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Article Materials Science, Multidisciplinary

Shape-memory polymers

Marc Behl et al.

MATERIALS TODAY (2007)

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Article Engineering, Biomedical

How useful is SBF in predicting in vivo bone bioactivity?

T Kokubo et al.

BIOMATERIALS (2006)

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Review Engineering, Biomedical

Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering

K Rezwan et al.

BIOMATERIALS (2006)

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Article Chemistry, Physical

Porous scaffold design for tissue engineering

SJ Hollister

NATURE MATERIALS (2005)

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Programmable, biodegradable composite scaffolds with variable pore morphology for minimal invasive bone repair

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