4.3 Article

Hepatocellular Carcinoma in Primary Biliary Cholangitis

期刊

CLINICS IN LIVER DISEASE
卷 26, 期 4, 页码 691-704

出版社

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cld.2022.06.011

关键词

Cirrhosis; Autoimmune liver disease; Epidemiology; Primary liver cancer

向作者/读者索取更多资源

Several studies have shown that patients with PBC have an increased risk of developing HCC. Risk factors for HCC in PBC include advanced age, male sex, comorbidities, and advanced liver fibrosis. The role of treatment response as a risk factor for HCC development in PBC patients should be further investigated. HCC in PBC has a poor prognosis compared to other chronic liver diseases with HCC, and liver transplantation offers the highest survival rate among available therapies.
Several studies have shown PBC to confer increased risk to develop HCC. Parameters recognized as risk factors for the development of HCC in PBC include advanced age, male sex, and comorbidities. Advanced liver fibrosis is the most significant risk factor. Moreover, future studies should aim to clarify the role of treatment response as a risk factor for HCC development in PBC patients. To date, the only indication for HCC screening that is agreed on by all scientific societies is in patients with cirrhosis. HCC in PBC carries a poor prognosis compared with other chronic liver diseases with HCC, and liver transplantation offers the best survival rate among available therapies.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.3
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据