☆ 4.5 Article

Modulation of Conformational Transition of Polypeptides under Slightly Acidic Environment†

CHINESE JOURNAL OF CHEMISTRY (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Chemistry, Multidisciplinary

Synthesis of Stimuli-Responsive Block Copolymers and Block Copolymer Nano-assemblies

Yuan Liu et al.

Summary: This research group has focused on exploring the synthesis and self-assembly of block copolymers, developing new thermo-responsive and photo-responsive polymers, and utilizing methods such as PISA for efficient synthesis of block copolymer nano-assemblies. Major emphasis has been placed on the thermo-responsive polymers based on dialkylamine groups, which have led to the synthesis of new stimuli-responsive block copolymer nano-assemblies.

CHINESE JOURNAL OF CHEMISTRY (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Stimuli-Responsive Nanoparticles for Controlled Drug Delivery in Synergistic Cancer Immunotherapy

Jin Zhang et al.

Summary: This review discusses the use of stimuli-responsive nanoparticles (srNPs) in cancer immunotherapy, highlighting their potential to enhance anti-tumor immune responses by combining with tumor microenvironment and external stimuli. The goal is to achieve synergistic immunotherapy and long-term immune memory to prevent tumor recurrence.

ADVANCED SCIENCE (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

ROS-Responsive Selenopolypeptide Micelles: Preparation, Characterization, and Controlled Drug Release

Chenglong Ge et al.

Summary: This study introduces a novel design of selenium-containing polypeptides that exhibit high sensitivity to reactive oxygen species (ROS) and show promising potential in drug delivery for cancer treatment.

BIOMACROMOLECULES (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Polymersomes: From Macromolecular Self-Assembly to Particle Assembly†

Jiamin Zhang et al.

Summary: This article introduces the importance of polymersomes in biomedical applications and research progress in macromolecular self-assembly, including polymersomes with different membrane structures and self-assembly methods based on NCA-PISA. These studies help address the biodegradability issue of nanoparticles and explore higher-order polymersome research.

CHINESE JOURNAL OF CHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Precise Control of Self-assembly in vivo Based on Polymer-Peptide Conjugates†

Yin-Sheng Xu et al.

Summary: This review highlights the application of self-assembled nanomaterials based on peptides in cancer treatment, focusing on the recent advances in in vivo self-assembly strategy. Different responsive assembly strategies have been developed to precisely control the diverse microenvironments of tumor cells, resulting in enhanced drug delivery and improved anticancer efficacy.

CHINESE JOURNAL OF CHEMISTRY (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Amphiphilic AIEgen-polymer aggregates: Design, self-assembly and biomedical applications

Shoupeng Cao et al.

Summary: Aggregation-induced emission (AIE) is a phenomenon where fluorescence is enhanced during molecular assembly, rather than quenched. AIE fluorogens are flexible, conjugated systems with limited dynamics when assembled, which improves their fluorescent properties. The integration of AIE design principles with versatile polymer chemistry has opened up new frontiers in nanoscience.

AGGREGATE (2022)

添加到收藏夹

Article Multidisciplinary Sciences

Addressing MRSA infection and antibacterial resistance with peptoid polymers

Jiayang Xie et al.

Summary: The article introduces antibacterial peptoid polymers prepared via NNCA ring-opening polymerization, demonstrating their effective antibacterial function against MRSA infection and potential therapeutic effects in vivo infection models, highlighting the great potential of peptoid polymers as promising antibacterial agents in treating MRSA infection and alleviating antibiotic resistance.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Ordered Conformation-Regulated Vesicular Membrane Permeability

Yi Zheng et al.

Summary: Synthetic polypeptide vesicles can regulate their permeability through ordered transition of secondary conformations, similar to biological systems, showing potential for controlled drug delivery applications.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

An Intracellular pH-Actuated Polymer for Robust Cytosolic Protein Delivery

Wei Xu et al.

Summary: A novel polymer G5-C4 was developed for robust cytosolic protein delivery through a pH-driven hydrophobic-to-hydrophilic transition, promoting efficient protein release and endosomal escape. Both in vitro and in vivo studies demonstrated superior antitumor effect of G5-C4.

CCS CHEMISTRY (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Recent advances in stimuli-responsive theranostic systems with aggregation-induced emission characteristics

Jing-Jing Hu et al.

Summary: The review summarizes the advancements in stimuli-responsive theranostic systems with AIE characteristics. These systems are classified based on treatment modes and stimuli types, with design strategies and application examples provided. The current state, limitations, and prospects of this technology are also discussed.

AGGREGATE (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Fluorescence imaging of pathophysiological microenvironments

Shan Wang et al.

Summary: Abnormal microenvironments play a significant role in various pathophysiological processes such as inflammation, neurodegenerative diseases, and cancer. Fluorescence imaging has emerged as a powerful tool for tracking changes in pathophysiological microenvironments, offering promising prospects for future development and application in fluorescent probes.

CHEMICAL SOCIETY REVIEWS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Surface Charge Switchable Supramolecular Nanocarriers for Nitric Oxide Synergistic Photodynamic Eradication of Biofilms

Dengfeng Hu et al.

ACS NANO (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Transformable peptide nanoparticles arrest HER2 signalling and cause cancer cell death in vivo

Lu Zhang et al.

NATURE NANOTECHNOLOGY (2020)

添加到收藏夹

Article Multidisciplinary Sciences

M2 amphipathic helices facilitate pH-dependent conformational transition in influenza A virus

Hedieh Torabifard et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

添加到收藏夹

Article Polymer Science

Streamlined Synthesis of PEG-Polypeptides Directly from Amino Acids

Tianrui Xue et al.

MACROMOLECULES (2020)

添加到收藏夹

Article Polymer Science

Manipulating the helix-coil transition profile of synthetic polypeptides by leveraging side-chain molecular interactions

Ziyuan Song et al.

POLYMER CHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Autocatalytic Morphology Transformation Platform for Targeted Drug Accumulation

Dong-Bing Cheng et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Endogenous Reactive Oxygen Species-Triggered Morphology Transformation for Enhanced Cooperative Interaction with Mitochondria

Dong-Bing Cheng et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Multidisciplinary Sciences

De novo design of tunable, pH-driven conformational changes

Scott E. Boyken et al.

SCIENCE (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enzyme-Instructed Peptide Assemblies Selectively Inhibit Bone Tumors

Zhaoqianqi Feng et al.

CHEM (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Influence of Sulfoxide Group Placement on Polypeptide Conformational Stability

Eric G. Gharakhanian et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Multidisciplinary Sciences

A tumour-selective cascade activatable self-detained system for drug delivery and cancer imaging

Hong-Wei An et al.

NATURE COMMUNICATIONS (2019)

添加到收藏夹

Article Chemistry, Physical

Acidity-triggered TAT-presenting nanocarriers augment tumor retention and nuclear translocation of drugs

Wei Jiang et al.

NANO RESEARCH (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Conformation-Directed Micelle-to-Vesicle Transition of Cholesterol Decorated Polypeptide Triggered by Oxidation

Hang Liu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

添加到收藏夹

Review Chemistry, Multidisciplinary

Secondary structures in synthetic polypeptides from N-carboxyanhydrides: design, modulation, association, and material applications

Ziyuan Song et al.

CHEMICAL SOCIETY REVIEWS (2018)

添加到收藏夹

Review Chemistry, Multidisciplinary

Peptide supramolecular materials for therapeutics

Kohei Sato et al.

CHEMICAL SOCIETY REVIEWS (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide

Misao Akishiba et al.

NATURE CHEMISTRY (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Selective killing of Helicobacter pylori with pH-responsive helix-coil conformation transitionable antimicrobial polypeptides

Menghua Xiong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Modulation of polypeptide conformation through donor-acceptor transformation of side-chain hydrogen bonding ligands

Ziyuan Song et al.

NATURE COMMUNICATIONS (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Bacteria-Assisted Activation of Antimicrobial Polypeptides by a Random-Coil to Helix Transition

Menghua Xiong et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Review Multidisciplinary Sciences

The activities of amyloids from a structural perspective

Roland Riek et al.

NATURE (2016)

添加到收藏夹

Article Nanoscience & Nanotechnology

A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy

Peng Mi et al.

Nature Nanotechnology (2016)

添加到收藏夹

Review Chemistry, Multidisciplinary

Bioresponsive polymeric nanotherapeutics for targeted cancer chemotherapy

Ru Cheng et al.

NANO TODAY (2015)

添加到收藏夹

Review Chemistry, Multidisciplinary

Smart Supramolecular Nanosystems for Bioimaging and Drug Delivery

Peipei Yang et al.

CHINESE JOURNAL OF CHEMISTRY (2015)

添加到收藏夹

Review Immunology

Perforin and granzymes: function, dysfunction and human pathology

Ilia Voskoboinik et al.

NATURE REVIEWS IMMUNOLOGY (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Multimodal Switching of Conformation and Solubility in Homocysteine Derived Polypeptides

Jessica R. Kramer et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

Light-Responsive Helical Polypeptides Capable of Reducing Toxicity and Unpacking DNA: Toward Nonviral Gene Delivery

Lichen Yin et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Glycopolypeptides with a Redox-Triggered Helix-to-Coil Transition

Jessica R. Kramer et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

添加到收藏夹

Article Chemistry, Multidisciplinary

pH-Responsive Bioactive Glycopolypeptides with Enhanced Helicity and Solubility in Aqueous Solution

Kai-Steffen Krannig et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

添加到收藏夹

Article Multidisciplinary Sciences

Ionic polypeptides with unusual helical stability

Hua Lu et al.

NATURE COMMUNICATIONS (2011)

添加到收藏夹

Article Multidisciplinary Sciences

pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path

Oleg A. Andreev et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

添加到收藏夹

Review Multidisciplinary Sciences

Dynamic personalities of proteins

Katherine Henzler-Wildman et al.

NATURE (2007)

添加到收藏夹

Article Chemistry, Physical

Stimuli-responsive polypeptide vesicles by conformation-specific assembly

EG Bellomo et al.

NATURE MATERIALS (2004)

添加到收藏夹

Article Chemistry, Multidisciplinary

The formation of polymer vesicles or peptosomes by polybutadiene-block-poly(L-glutamate)s in dilute aqueous solution

H Kukula et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.