Molecularly Imprinted Electrochemical Sensor Based on Nitrogen-doped Molybdenum Carbide Nanosphere for Trace Analysis of Resveratrol

A novel molecularly imprinted electrochemical sensor based on nitrogen-doped molybdenum carbide(N-Mo2C) nanosphere was fabricated for trace analysis of resveratrol in this work. N-Mo2C with large specific surface area and good electrical conductivity was introduced to construct a sensitive imprinting platform. Molecularly imprinted polymer film was prepared through a simple electropolymerization method using resveratrol as the template molecule and o-phenylenediamine as the functional monomer. The sensor shows great analytical performance in the concentration range of 10(-9) mol L-1 to 10(-4) mol L(-1)and the detection limit is as low as 4.37x10(-10) mol L-1. The sensor also has the advantages of good selectivity, reproducibility and stability, which opens a new way for the application of molecularly imprinted electrochemical sensors in the field ofbiomedicine detection.

Automated summary

A novel molecularly imprinted electrochemical sensor based on nitrogen-doped molybdenum carbide nanosphere was developed for trace analysis of resveratrol. The sensor exhibited excellent analytical performance with good selectivity, reproducibility, and stability.