相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。A review towards synthesis of heterocycles using propargyl alcohols and propargyl amines
Amit Ranjan Pandey et al.
MONATSHEFTE FUR CHEMIE (2022)
Diversity-oriented synthesis as a tool to expand the chemical space of DNA-encoded libraries
Elena Lenci et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2021)
Small-Molecule Inhibitors Overcome Epigenetic Reprogramming for Cancer Therapy
Wenjing Xiao et al.
FRONTIERS IN PHARMACOLOGY (2021)
Targeting RNA with small molecules: from fundamental principles towards the clinic
James P. Falese et al.
CHEMICAL SOCIETY REVIEWS (2021)
Iodocyclisation of Electronically Resistant Alkynes: Synthesis of 2-Carboxy (and sulfoxy)-3-iodobenzo[b]thiophenes
Shuqi Chen et al.
AUSTRALIAN JOURNAL OF CHEMISTRY (2021)
Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age
Rita Ferreira et al.
CELLS (2020)
Synthesis of Seleno-Heterocycles via Electrophilic/Radical Cyclization of Alkyne Containing Heteroatoms
Amol D. Sonawane et al.
ADVANCED SYNTHESIS & CATALYSIS (2020)
Targeting RNA structures in diseases with small molecules
Yanqiu Shao et al.
SPOTLIGHT ON CHINA: RNA (2020)
Small molecules with big roles in microRNA chemical biology and microRNA-targeted therapeutics
Rengen Fan et al.
RNA BIOLOGY (2019)
Strategies for the Diversity-Oriented Synthesis of Macrocycles
Kim T. Mortensen et al.
CHEMICAL REVIEWS (2019)
Targeting Topoisomerase I in the Era of Precision Medicine
Anish Thomas et al.
CLINICAL CANCER RESEARCH (2019)
Modulation of DNA structure formation using small molecules
Imee M. A. del Mundo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2019)
Next generation diversity-oriented synthesis: a paradigm shift from chemical diversity to biological diversity
Ivan Pavlinov et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2019)
Chemical probes and drug leads from advances in synthetic planning and methodology
Christopher J. Gerry et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Principles for targeting RNA with drug-like small molecules
Katherine Deigan Warner et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Mechanistic studies of a small-molecule modulator of SMN2 splicing
Jingxin Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
A Brief Overview of Two Major Strategies in Diversity-Oriented Synthesis: Build/Couple/Pair and Ring-Distortion
Sihyeong Yi et al.
FRONTIERS IN CHEMISTRY (2018)
Linear and Angular Heteroacenes from Double-Electrophilic Cyclization (DEC) and DEC-Reductive Elimination of Diynes
Akhil Gupta et al.
ORGANIC LETTERS (2017)
Targeting transcription factors by small compounds-Current strategies and future implications
Judith Hagenbuchner et al.
BIOCHEMICAL PHARMACOLOGY (2016)
Noncovalent Binding to DNA: Still a Target in Developing Anticancer Agents
Jose Portugal et al.
CURRENT MEDICINAL CHEMISTRY (2016)
From Sphingosine Kinase to Dihydroceramide Desaturase: A Structure-Activity Relationship (SAR) Study of the Enzyme Inhibitory and Anticancer Activity of 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol (SKI-II)
Luigi Aurelio et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery
Thomas G. Davies et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Electrophilic Activation of P-Alkynes in the Synthesis of P-Substituted and P-Centered Heterocycles
Akhil Gupta et al.
JOURNAL OF ORGANIC CHEMISTRY (2016)
A Small Molecule That Represses Translation of G-Quadruplex-Containing mRNA
Yousuke Katsuda et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Iodine-mediated synthesis of heterocycles via electrophilic cyclization of alkynes
Trapti Aggarwal et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2016)
The Emerging Role of RNA as a Therapeutic Target for Small Molecules
Colleen M. Connelly et al.
CELL CHEMICAL BIOLOGY (2016)
Recent Advances in Developing Small Molecules Targeting Nucleic Acid
Maolin Wang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Interfacial inhibitors
Yves Pommier et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
Silver-catalysed reactions of alkynes: recent advances
Guichun Fang et al.
CHEMICAL SOCIETY REVIEWS (2015)
Mapping the Interactions of I2, I., I-, and I+ with Alkynes and Their Roles in Iodocyclizations
Rohan Volpe et al.
CHEMISTRY-A EUROPEAN JOURNAL (2015)
Inhibitory Effect of the Noncamptothecin Topoisomerase I Inhibitor LMP-400 on Female Mice Models and Human Pheochromocytoma Cells
Jan Schovanek et al.
ENDOCRINOLOGY (2015)
Synthesis of Thieno-Fused Heterocycles through Reiterative Iodocyclization
Luigi Aurelio et al.
ADVANCED SYNTHESIS & CATALYSIS (2014)
Targeting a c-MYC G-quadruplex DNA with a fragment library
Hamid R. Nasiri et al.
CHEMICAL COMMUNICATIONS (2014)
The Expanding View of RNA and DNA Function
Ronald R. Breaker et al.
CHEMISTRY & BIOLOGY (2014)
Nickel-Catalyzed Reductive Cyclization of Alkyl Dihalides
Weichao Xue et al.
ORGANIC LETTERS (2014)
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
Nikolai A. Naryshkin et al.
SCIENCE (2014)
Structure-Based DNA-Targeting Strategies with Small Molecule Ligands for Drug Discovery
Jia Sheng et al.
MEDICINAL RESEARCH REVIEWS (2013)
Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor
Chao Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
A selective synthesis of 4-bromoisoquinoline and 4-bromoisquinolone
Hong-Ping Zhang et al.
JOURNAL OF CHEMICAL RESEARCH (2013)
Synthesis and properties of macrocyclic diazene switch with binaphthalene unit attached via acrylamide linkers
Anna Kickova et al.
CHEMICAL PAPERS (2013)
Cyclizations of Alkynes: Revisiting Baldwin's Rules for Ring Closure
Kerry Gilmore et al.
CHEMICAL REVIEWS (2011)
Synthesis of 2-Halogenated Quinolines by Halide-Mediated Intramolecular Cyclization of o-Alkynylaryl Isocyanides
Takenori Mitamura et al.
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN (2010)
MPHT-Promoted Bromocyclization of ortho-Substituted Arylalkynes: Application to the Synthesis of 2-Substituted 3-Bromobenzofurans and -Benzo[b]thiophenes
Maud Jacubert et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2010)
Richter cyclization and co-cyclization reactions of triazene-masked diazonium ions
Annelies Goeminne et al.
TETRAHEDRON LETTERS (2010)
Synthesis of Functionalized Isoquinolines via Sequential Cyclization/Cross-Coupling Reactions
Xingxin Yu et al.
JOURNAL OF COMBINATORIAL CHEMISTRY (2009)
The indenoisoquinoline noncamptothecin topoisomerase I inhibitors: update and perspectives
Yves Pommier et al.
MOLECULAR CANCER THERAPEUTICS (2009)
Syntheses and biological evaluation of topoisomerase I-targeting agents related to 11-[2-(N,N-dimethylamino)ethyl]-2,3-dimethoxy-8,9methylenedioxy-11H-isoquino[4,3-c]cinnolin-12-one (ARC-31)
Mavurapu Satyanarayana et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
DNA cleavage assay for the identification of topoisomerase I inhibitors
Thomas S. Dexheimer et al.
NATURE PROTOCOLS (2008)
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
James Tsai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Cu-catalyzed tandem C-N bond formation for the synthesis of pyrroles and heteroarylpyrroles
Ruben Martin et al.
ORGANIC LETTERS (2007)
ARC-111 inhibits hypoxia-mediated hypoxia-inducible factor-1α accumulation
Fanying Meng et al.
ANTI-CANCER DRUGS (2007)
Topoisomerase I inhibitors: camptothecins and beyond
Yves Pommier
NATURE REVIEWS CANCER (2006)
Diversity-oriented synthesis of 3-iodochromones and heteroatom analogues via ICl-induced cyclization
CX Zhou et al.
JOURNAL OF ORGANIC CHEMISTRY (2006)
A novel norindenoisoquinoline structure reveals a common interfacial inhibitor paradigm for ternary trapping of the topoisomerase I-DNA covalent complex
C Marchand et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Selective endo and exo iodocyclizations in the synthesis of Quinolines and Indoles
KO Hessian et al.
ORGANIC LETTERS (2006)
Diversity-oriented synthesis: exploring the intersections between chemistry and biology
DS Tan
NATURE CHEMICAL BIOLOGY (2005)
The search of DNA-intercalators as antitumoral drugs: what it worked and what did not work
R Martinez et al.
CURRENT MEDICINAL CHEMISTRY (2005)
Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: Mechanism and therapeutic implications
A Rapisarda et al.
CANCER RESEARCH (2004)
11H-Isoquino[4,3-c]cinnolin-12-ones:: novel anticancer agents with potent topoisomerase I-targeting activity and cytotoxicity
AL Ruchelman et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2004)
Synthesis of substituted isoquinolines by electrophilic cyclization of iminoalkynes
QH Huang et al.
JOURNAL OF ORGANIC CHEMISTRY (2002)
分享论文
