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BREAST CANCER RESEARCH (2018)
Protein Lipidation in Cell Signaling and Diseases: Function, Regulation, and Therapeutic Opportunities
Baoen Chen et al.
CELL CHEMICAL BIOLOGY (2018)
Plasma cholesterol and lipoprotein levels in relation to tumor aggressiveness and survival in HCC patients
Brian Carr et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS (2018)
Colorectal Cancer Cells Increase the Production of Short Chain Fatty Acids by Propionibacterium freudenreichii Impacting on Cancer Cells Survival
Marta R. Casanova et al.
FRONTIERS IN NUTRITION (2018)
Sphingolipid metabolism in cancer signalling and therapy
Besim Ogretmen
NATURE REVIEWS CANCER (2018)
Increased dietary levels of α-linoleic acid inhibit mammary tumor growth and metastasis
Marianela Vara-Messler et al.
EUROPEAN JOURNAL OF NUTRITION (2017)
Association between Body Mass Index and Cancer Survival in a Pooled Analysis of 22 Clinical Trials
Heather Greenlee et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2017)
Targeting metastasis-initiating cells through the fatty acid receptor CD36
Gloria Pascual et al.
NATURE (2017)
Functional Lipidomics: Palmitic Acid Impairs Hepatocellular Carcinoma Development by Modulating Membrane Fluidity and Glucose Metabolism
Ling Lin et al.
HEPATOLOGY (2017)
Adipocytes promote cholangiocarcinoma metastasis through fatty acid binding protein 4
Jihua Nie et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2017)
Genome-wide in vivo screen identifies novel host regulators of metastatic colonization
Louise van der Weyden et al.
NATURE (2017)
Palmitoylation-dependent activation of MC1R prevents melanomagenesis
Shuyang Chen et al.
NATURE (2017)
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
Vasanthi S. Viswanathan et al.
NATURE (2017)
Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF
Daniela F. Quail et al.
NATURE CELL BIOLOGY (2017)
SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology
Hitoshi Shimano et al.
NATURE REVIEWS ENDOCRINOLOGY (2017)
The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells
Amy E. Baek et al.
NATURE COMMUNICATIONS (2017)
Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer
Filippo Veglia et al.
NATURE COMMUNICATIONS (2017)
Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a
Matteo Spinelli et al.
NATURE COMMUNICATIONS (2017)
Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism
Thomas Farge et al.
CANCER DISCOVERY (2017)
SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a
Hui Jing et al.
ELIFE (2017)
Impact of Metabolism in on T-Cell Differentiation and Function and Cross Talk with Tumor Microenvironment
Soumaya Kouidhi et al.
FRONTIERS IN IMMUNOLOGY (2017)
Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells
Amir A. Al-Khami et al.
ONCOIMMUNOLOGY (2017)
Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β
Dequina A. Nicholas et al.
PLOS ONE (2017)
Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence
Marcos Rios Garcia et al.
CELL METABOLISM (2017)
Differences in elongation of very long chain fatty acids and fatty acid metabolism between triple-negative and hormone receptor-positive breast cancer
Yuji Yamashita et al.
BMC CANCER (2017)
Update on obesity (with and without diabetes)
A. Hamann
DIABETOLOGE (2017)
Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells
Junjie Li et al.
CELL STEM CELL (2017)
APT2 Inhibition Restores Scribble Localization and S-Palmitoylation in Snail-Transformed Cells
Jeannie L. Hernandez et al.
CELL CHEMICAL BIOLOGY (2017)
Palmitic acid increases invasiveness of pancreatic cancer cells AsPC-1 through TLR4/ROS/NF-κB/MMP-9 signaling pathway
Makena J. Binker-Cosen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration
Seher Balaban et al.
CANCER & METABOLISM (2017)
Obesity, Inflammation, and Cancer
Tuo Deng et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 11 (2016)
Candidate Antimetastasis Drugs Suppress the Metastatic Capacity of Breast Cancer Cells by Reducing Membrane Fluidity
Weina Zhao et al.
CANCER RESEARCH (2016)
Emerging roles for lipids in non-apoptotic cell death
L. Magtanong et al.
CELL DEATH AND DIFFERENTIATION (2016)
Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche
Haobin Ye et al.
CELL STEM CELL (2016)
Oleic acid-embedded nanoliposome as a selective tumoricidal agent
Sujin Jung et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2016)
Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling
Kristin B. Runkle et al.
MOLECULAR CELL (2016)
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors
Semir Beyaz et al.
NATURE (2016)
Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway
PuiYee Chan et al.
NATURE CHEMICAL BIOLOGY (2016)
ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity
Baoen Chen et al.
NATURE CHEMICAL BIOLOGY (2016)
Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer
Roman Camarda et al.
NATURE MEDICINE (2016)
Body Fatness and Cancer - Viewpoint of the IARC Working Group
Beatrice Lauby-Secretan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Palmitoylation of TEAD Transcription Factors Is Required for Their Stability and Function in Hippo Pathway Signaling
Cameron L. Noland et al.
STRUCTURE (2016)
SREBP-1 is an independent prognostic marker and promotes invasion and migration in breast cancer
Jisheng Bao et al.
ONCOLOGY LETTERS (2016)
Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis
Mahesh S. Padanad et al.
CELL REPORTS (2016)
Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers
Aritro Nath et al.
SCIENTIFIC REPORTS (2016)
Palmitoylation: a protein S-acylation with implications for breast cancer
Alison M. Anderson et al.
NPJ BREAST CANCER (2016)
ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis
Juan R. Cubillos-Ruiz et al.
CELL (2015)
Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity
Santiago Zelenay et al.
CELL (2015)
Lipid Metabolism, Apoptosis and Cancer Therapy
Chunfa Huang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Protein Depalmitoylation Is Induced by Wnt5a and Promotes Polarized Cell Behavior
Wei Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
CD36 Binds Oxidized Low Density Lipoprotein (LDL) in a Mechanism Dependent upon Fatty Acid Binding
Anthony G. Jay et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
A Review of Odd-Chain Fatty Acid Metabolism and the Role of Pentadecanoic Acid (C15:0) and Heptadecanoic Acid (C17:0) in Health and Disease
Benjamin Jenkins et al.
MOLECULES (2015)
Notum deacylates Wnt proteins to suppress signalling activity
Satoshi Kakugawa et al.
NATURE (2015)
Obesity Triggers Enhanced MDSC Accumulation in Murine Renal Tumors via Elevated Local Production of CCL2
Malika Hale et al.
PLOS ONE (2015)
Intracellular activation of EGFR by fatty acid synthase dependent palmitoylation
Lakshmi Reddy Bollu et al.
ONCOTARGET (2015)
Radiation-driven lipid accumulation and dendritic cell dysfunction in cancer
Fu Gao et al.
Scientific Reports (2015)
Mediterranean Diet and Invasive Breast Cancer Risk Among Women at High Cardiovascular Risk in the PREDIMED Trial A Randomized Clinical Trial
Estefania Toledo et al.
JAMA INTERNAL MEDICINE (2015)
Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies
Fokhrul Hossain et al.
CANCER IMMUNOLOGY RESEARCH (2015)
Dietary Fat Without Body Weight Gain Increases In Vivo MCF-7 Human Breast Cancer Cell Growth and Decreases Natural Killer Cell Cytotoxicity
Bruno Lamas et al.
MOLECULAR CARCINOGENESIS (2015)
Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma
Aritro Nath et al.
SCIENTIFIC REPORTS (2015)
Mislocalization of the Cell Polarity Protein Scribble Promotes Mammary Tumorigenesis and Is Associated with Basal Breast Cancer
Michael E. Feigin et al.
CANCER RESEARCH (2014)
Obesity, Rather Than Diet, Drives Epigenomic Alterations in Colonic Epithelium Resembling Cancer Progression
Ruifang Li et al.
CELL METABOLISM (2014)
Targeting SREBP-1-driven Lipid Metabolism to Treat Cancer
Deliang Guo et al.
CURRENT PHARMACEUTICAL DESIGN (2014)
SREBP-1 Has a Prognostic Role and Contributes to Invasion and Metastasis in Human Hepatocellular Carcinoma
Chao Li et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
Oxidized Lipids Block Antigen Cross-Presentation by Dendritic Cells in Cancer
Wei Cao et al.
JOURNAL OF IMMUNOLOGY (2014)
The Fatty Acid Synthase Inhibitor Orlistat Reduces the Growth and Metastasis of Orthotopic Tongue Oral Squamous Cell Carcinomas
Michelle Agostini et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Effects of a Diet Rich in n-3 Polyunsaturated Fatty Acids on Hepatic Lipogenesis and Beta-Oxidation in Mice
Thereza C. Lonzetti Bargut et al.
LIPIDS (2014)
A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway
Morvarid Mohseni et al.
NATURE CELL BIOLOGY (2014)
Effects of a High-Fat Diet on Spontaneous Metastasis of Lewis Lung Carcinoma in Plasminogen Activator Inhibitor-1 Deficient and Wild-Type Mice
Lin Yan et al.
PLOS ONE (2014)
SREBP: a novel therapeutic target
Xu Xiao et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2013)
Preventing Postoperative Metastatic Disease by Inhibiting Surgery-Induced Dysfunction in Natural Killer Cells
Lee-Hwa Tai et al.
CANCER RESEARCH (2013)
27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology
Erik R. Nelson et al.
SCIENCE (2013)
Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties
Philippe de Medina et al.
NATURE COMMUNICATIONS (2013)
Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms
Mackenzie K. Herroon et al.
ONCOTARGET (2013)
Current evidence linking polyunsaturated fatty acids with cancer risk and progression
Maria Azrad et al.
FRONTIERS IN ONCOLOGY (2013)
PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice
B. Shen et al.
BRITISH JOURNAL OF CANCER (2012)
The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas
F. Seguin et al.
BRITISH JOURNAL OF CANCER (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Short-Chain Fatty Acids Induce Apoptosis in Colon Cancer Cells Associated with Changes to Intracellular Redox State and Glucose Metabolism
Geoffrey M. Matthews et al.
CHEMOTHERAPY (2012)
A metabolic prosurvival role for PML in breast cancer
Arkaitz Carracedo et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Diet-Induced Obesity Alters Dendritic Cell Function in the Presence and Absence of Tumor Growth
Britnie R. James et al.
JOURNAL OF IMMUNOLOGY (2012)
Statin Use and Reduced Cancer-Related Mortality
Sune F. Nielsen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Phospholipase signalling networks in cancer
Jong Bae Park et al.
NATURE REVIEWS CANCER (2012)
A Randomized Trial of Dietary Intervention for Breast Cancer Prevention
Lisa J. Martin et al.
CANCER RESEARCH (2011)
Oleate Blocks Palmitate-Induced Abnormal Lipid Distribution, Endoplasmic Reticulum Expansion and Stress, and Insulin Resistance in Skeletal Muscle
Gong Peng et al.
ENDOCRINOLOGY (2011)
Effect of Obesity on Prognosis After Early-Stage Breast Cancer
Marianne Ewertz et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
Kristin M. Nieman et al.
NATURE MEDICINE (2011)
Dietary fat increases solid tumor growth and metastasis of 4T1 murine mammary carcinoma cells and mortality in obesity-resistant BALB/c mice
Eun Ji Kim et al.
BREAST CANCER RESEARCH (2011)
Palmitoylation of oncogenic NRAS is essential for leukemogenesis
Benjamin Cuiffo et al.
BLOOD (2010)
Elevated dietary linoleic acid increases gastric carcinoma cell invasion and metastasis in mice
T. Matsuoka et al.
BRITISH JOURNAL OF CANCER (2010)
De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation
Evelien Rysman et al.
CANCER RESEARCH (2010)
Oleic acid promotes MMP-9 secretion and invasion in breast cancer cells
Adriana Soto-Guzman et al.
CLINICAL & EXPERIMENTAL METASTASIS (2010)
Increased Mitochondrial Fatty Acid Oxidation Is Sufficient to Protect Skeletal Muscle Cells from Palmitate-induced Apoptosis
Carole Henique et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
DHHC20: a human palmitoyl acyltransferase that causes cellular transformation
Jeremiah M. Draper et al.
MOLECULAR MEMBRANE BIOLOGY (2010)
The Complex and Important Cellular and Metabolic Functions of Saturated Fatty Acids
Philippe Legrand et al.
LIPIDS (2010)
N-3 polyunsaturated fatty acids suppress insulin-induced SREBP-1c transcription via reduced trans-activating capacity of LXRα
George Howell et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2009)
Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes
Matteo Ricchi et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2009)
Effect of low-fat diet on development of prostate cancer and Akt phosphorylation in the Hi-Myc transgenic mouse model
Naoko Kobayashi et al.
CANCER RESEARCH (2008)
In rat hepatocytes, myristic acid occurs through lipogenesis, palmitic acid shortening and lauric acid elongation
V. Rioux et al.
ANIMAL (2007)
Increase in fluidity in the membrane of MT3 breast cancer cells correlates with enhanced cell adhesion in vitro and increased lung metastasis in NOD/SCID mice
Reiner Zeisig et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)
Gain of 5p15.33 is associated with progression of bladder cancer
Yoshiaki Yamamoto et al.
ONCOLOGY (2007)
Dietary fat reduction and breast cancer outcome: Interim efficacy results from the Women's Intervention Nutrition Study
Rowan T. Chlebowski et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)
ATP citrate lyase inhibition can suppress tumor cell growth
G Hatzivassiliou et al.
CANCER CELL (2005)
Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erb B-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin™) in breast cancer cells with Her-2/neu oncogene amplification
JA Menendez et al.
ANNALS OF ONCOLOGY (2005)
Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution
CN Serhan
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2005)
Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase
CE Ducker et al.
ONCOGENE (2004)
Triglyceride accumulation protects against fatty acid-induced lipotoxicity
LL Listenberger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Does a linolenic acid in combination with linoleic acid influence liver metastasis and hepatic lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters?
FA Wenger et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2000)