4.7 Article

Etomoxir, a carnitine palmitoyltransferase 1 inhibitor, combined with temozolomide reduces stemness and invasiveness in patient-derived glioblastoma tumorspheres

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

A novel biguanide (IM1761065) inhibits bioenergetics of glioblastoma tumorspheres

Tae Hoon Roh et al.

Summary: IM1761065 is a potent inhibitor of oxidative phosphorylation in GBM-TS, showing significant effects on reducing viability, stemness, and invasive properties of tumorspheres. The compound also exhibited promising results in in vivo mouse models, suggesting its potential as a new drug for GBM treatment.

JOURNAL OF NEURO-ONCOLOGY (2022)

Article Biotechnology & Applied Microbiology

Fatty acid beta-oxidation promotes breast cancer stemness and metastasis via the miRNA-328-3p-CPT1A pathway

Feng Zeng et al.

Summary: MiR-328-3p is significantly downregulated in breast cancer, especially in patients with metastasis. The miR-328-3p/CPT1A/fatty acid beta-oxidation/stemness axis has been shown to be responsible for breast cancer metastasis. This study suggests that miR-328-3p could be a potential therapeutic target for breast cancer patients with metastasis.

CANCER GENE THERAPY (2022)

Review Oncology

High ATP Production Fuels Cancer Drug Resistance and Metastasis: Implications for Mitochondrial ATP Depletion Therapy

Marco Fiorillo et al.

Summary: The study suggests that high mitochondrial ATP production is a new therapeutic target for cancer treatment, isolating metabolically fit cancer cells with enhanced stem-like properties and invasive abilities. By regulating mitochondrial ATP-synthase, prevention of metastasis in cancer cells is possible.

FRONTIERS IN ONCOLOGY (2021)

Review Oncology

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary

David N. Louis et al.

Summary: The fifth edition of the WHO Classification of Tumors of the Central Nervous System integrates molecular diagnostics into CNS tumor classification, introduces different approaches to tumor nomenclature and grading, and emphasizes the importance of integrated diagnoses and layered reports.

NEURO-ONCOLOGY (2021)

Article Oncology

Combined effects of niclosamide and temozolomide against human glioblastoma tumorspheres

Hyeong-Cheol Oh et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2020)

Article Multidisciplinary Sciences

Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy

Charles P. Couturier et al.

NATURE COMMUNICATIONS (2020)

Review Clinical Neurology

Glioblastoma Cellular Origin and the Firework Pattern of Cancer Genesis from the Subventricular Zone

Seon-Jin Yoon et al.

JOURNAL OF KOREAN NEUROSURGICAL SOCIETY (2020)

Article Biochemistry & Molecular Biology

Potential involvement of Drosophila flightless-1 in carbohydrate metabolism

Jung-Eun Park et al.

BMB REPORTS (2018)

Article Medicine, Research & Experimental

Metabolic shifts in residual breast cancer drive tumor recurrence

Kristina M. Havas et al.

JOURNAL OF CLINICAL INVESTIGATION (2017)

Article Oncology

The clinical value of patient-derived glioblastoma tumorspheres in predicting treatment response

Quintino Giorgio D'Alessandris et al.

NEURO-ONCOLOGY (2017)

Review Oncology

Hallmarks of cancer stem cell metabolism

Patricia Sancho et al.

BRITISH JOURNAL OF CANCER (2016)

Article Biochemistry & Molecular Biology

Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer

Roman Camarda et al.

NATURE MEDICINE (2016)

Review Biochemistry & Molecular Biology

The Warburg Effect: How Does it Benefit Cancer Cells?

Maria V. Liberti et al.

TRENDS IN BIOCHEMICAL SCIENCES (2016)

Review Multidisciplinary Sciences

Fundamentals of cancer metabolism

Ralph J. DeBerardinis et al.

SCIENCE ADVANCES (2016)

Article Oncology

The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment

Laura Annovazzi et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2015)

Review Cell Biology

Metabolic pathways promoting cancer cell survival and growth

Lindsey K. Boroughs et al.

NATURE CELL BIOLOGY (2015)

Article Oncology

Lipid Catabolism via CPT1 as a Therapeutic Target for Prostate Cancer

Isabel R. Schlaepfer et al.

MOLECULAR CANCER THERAPEUTICS (2014)

Article Clinical Neurology

Isolation of glioma cancer stem cells in relation to histological grades in glioma specimens

Byung Ho Kong et al.

CHILDS NERVOUS SYSTEM (2013)

Review Biotechnology & Applied Microbiology

Metabolic targets for cancer therapy

Lorenzo Galluzzi et al.

NATURE REVIEWS DRUG DISCOVERY (2013)

Article Biochemistry & Molecular Biology

Ensembl 2013

Paul Flicek et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Biochemical Research Methods

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

Cole Trapnell et al.

NATURE PROTOCOLS (2012)

Article Medicine, Research & Experimental

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

Ismael Samudio et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Review Multidisciplinary Sciences

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

Matthew G. Vander Heiden et al.

SCIENCE (2009)

Review Pharmacology & Pharmacy

Multiple drug resistance in cancer revisited: The cancer stem cell hypothesis

VS Donnenberg et al.

JOURNAL OF CLINICAL PHARMACOLOGY (2005)

Article Medicine, General & Internal

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

R Stupp et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Biochemistry & Molecular Biology

Impact of mitochondrial beta-oxidation in fatty acid-mediated inhibition of glioma cell proliferation

K Berge et al.

JOURNAL OF LIPID RESEARCH (2003)

Article Clinical Neurology

An implantable guide-screw system for brain tumor studies in small animals

S Lal et al.

JOURNAL OF NEUROSURGERY (2000)