☆ 4.6 Editorial Material

Irradiation-free, T-cell replete haploidentical transplant for Fanconi anaemia, weighing the benefits

BRITISH JOURNAL OF HAEMATOLOGY (2022)

Transplantation for Fanconi anaemia: lessons learned from Brazil

Carmem Bonfim et al.

Lancet Haematology (2022)

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Article Hematology

Unmanipulated haploidentical haematopoietic cell transplantation with radiation-free conditioning in Fanconi anaemia: A retrospective analysis from the Chinese Blood and Marrow Transplantation Registry Group

Lanping Xu et al.

Summary: This study analyzed the outcomes of unmanipulated haploidentical hematopoietic cell transplantation (HCT) with radiation-free conditioning in patients with Fanconi anemia. The results showed favorable engraftment and survival rates, but relatively high incidences of acute and chronic graft-versus-host disease (GvHD).

BRITISH JOURNAL OF HAEMATOLOGY (2022)

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Article Hematology

Haplo-identical or mismatched unrelated donor hematopoietic cell transplantation for Fanconi anemia: Results from the Severe Aplastic Anemia Working Party of the EBMT

Josune Zubicaray et al.

Summary: Allogeneic hematopoietic cell transplantation is the only cure for Fanconi anemia (FA), but alternative donors like haplo-identical donors may offer better outcomes. Transplantation with haplo-identical donors with only in vivo T cell depletion may lead to better event-free survival (EFS) for FA patients.

AMERICAN JOURNAL OF HEMATOLOGY (2021)

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Letter Medicine, General & Internal