相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Development of small-molecule tropomyosin receptor kinase (TRK) inhibitors for NTRK fusion cancers
Tingting Jiang et al.
ACTA PHARMACEUTICA SINICA B (2021)
Discovery of novel 2-phenylamino-4-prolylpyrimidine derivatives as TRK/ALK dual inhibitors with promising antitumor effects
Tong Li et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2021)
Discovery of First-In-Class Potent and Selective Tropomyosin Receptor Kinase Degraders
Liqun Chen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Design, synthesis and biological evaluation of 3-(imidazo[1,2-a] pyrazin-3-ylethynyl)-2-methylbenzamides as potent and selective pan-tropomyosin receptor kinase (TRK) inhibitors
Shengyang Cui et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Repotrectinib (TPX-0005) Is a Next-Generation ROS1/TRK/ALK Inhibitor That Potently Inhibit ROS1/TRK/ALK Solvent-Front Mutations
Alexander Drilon et al.
CANCER DISCOVERY (2018)
NTRK fusion-positive cancers and TRK inhibitor therapy
Emiliano Cocco et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors
Alexander Drilon et al.
CANCER DISCOVERY (2017)
The efficacy of larotrectinib (LOXO-101), a selective tropomyosin receptor kinase (TRK) inhibitor, in adult and pediatric TRK fusion cancers.
David Michael Hyman et al.
JOURNAL OF CLINICAL ONCOLOGY (2017)
Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer
Mariangela Russo et al.
CANCER DISCOVERY (2016)
What hides behind the MASC: clinical response and acquired resistance to entrectinib after ETV6-NTRK3 identification in a mammary analogue secretory carcinoma (MASC)
A. Drilon et al.
ANNALS OF ONCOLOGY (2016)
TPX-0005, a novel ALK/ROS1/TRK inhibitor, effectively inhibited a broad spectrum of mutations including solvent front ALK G1202R, ROS1 G2032R and TRKA G595R mutants
J. J. Cui et al.
EUROPEAN JOURNAL OF CANCER (2016)
The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain
Sarah E. Skerratt et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor
Maria Menichincheri et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101
Robert C. Doebele et al.
CANCER DISCOVERY (2015)
TrkB inhibition by GNF-4256 slows growth and enhances chemotherapeutic efficacy in neuroblastoma xenografts
Jamie L. Croucher et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2015)
Discovery of Novel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent Inhibitory Activities against Both Wild-type and Mutant ALK Kinases
Zilan Song et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
TRKing Down an Old Oncogene in a New Era of Targeted Therapy
Aria Vaishnavi et al.
CANCER DISCOVERY (2015)
Functional Characterization of NTRK1 Mutations Identified in Melanoma
Claudia Miranda et al.
GENES CHROMOSOMES & CANCER (2014)
Discovery of GNF-5837, a Selective TRK Inhibitor with Efficacy in Rodent Cancer Tumor Models
Pam Albaugh et al.
ACS MEDICINAL CHEMISTRY LETTERS (2012)
A plant kinase plays roles in defense response against geminivirus by phosphorylation of a viral pathogenesis protein
Qingtang Shen et al.
PLANT SIGNALING & BEHAVIOR (2012)
Functional Characterization of Human Cancer-Derived TRKB Mutations
Thomas R. Geiger et al.
PLOS ONE (2011)
TrkA overexpression enhances growth and metastasis of breast cancer cells
C. Lagadec et al.
ONCOGENE (2009)
Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia
Michael H. Tomasson et al.
BLOOD (2008)
ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin
HK Teng et al.
JOURNAL OF NEUROSCIENCE (2005)
Neurotrophins: Roles in neuronal development and function
EJ Huang et al.
ANNUAL REVIEW OF NEUROSCIENCE (2001)
Development of sensory neurons in the absence of NGF/TrkA signaling in vivo
TD Patel et al.
NEURON (2000)
分享论文
