相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Manganese-phenolic nanoadjuvant combines sonodynamic therapy with cGAS-STING activation for enhanced cancer immunotherapy
Hao Tian et al.
NANO TODAY (2022)
Manganese enhances the antitumor function of CD8+ T cells by inducing type I interferon production
Yuan Song et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2021)
cGAS-STING signaling in cancer immunity and immunotherapy
Huashan Du et al.
BIOMEDICINE & PHARMACOTHERAPY (2021)
Maintaining manganese in tumor to activate cGAS-STING pathway evokes a robust abscopal anti-tumor effect
Chao Wang et al.
JOURNAL OF CONTROLLED RELEASE (2021)
Overview of STING-Associated Vasculopathy with Onset in Infancy (SAVI) Among 21 Patients
Marie-Louise Fremond et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)
Manganese salts function as potent adjuvants
Rui Zhang et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2021)
Molecular Targets of Manganese-Induced Neurotoxicity: A Five-Year Update
Alexey A. Tinkov et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
NLRP3 inflammasome activation and cell death
Yi Huang et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2021)
A current view on Tau protein phosphorylation in Alzheimer's disease
Susanne Wegmann et al.
CURRENT OPINION IN NEUROBIOLOGY (2021)
The cGAS-STING pathway as a therapeutic target in inflammatory diseases
Alexiane Decout et al.
NATURE REVIEWS IMMUNOLOGY (2021)
Structural Insights into STING Signaling
Sabrina L. Ergun et al.
TRENDS IN CELL BIOLOGY (2020)
Manganese-Based Nanoactivator Optimizes Cancer Immunotherapy via Enhancing Innate Immunity
Lin Hou et al.
ACS NANO (2020)
Brain manganese and the balance between essential roles and neurotoxicity
Rekha C. Balachandran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
STING promotes NLRP3 localization in ER and facilitates NLRP3 deubiquitination to activate the inflammasome upon HSV-1 infection
Wenbiao Wang et al.
PLoS Pathogens (2020)
Allosteric coupling between Mn2+ and dsDNA controls the catalytic efficiency and fidelity of cGAS
Richard M. Hooy et al.
NUCLEIC ACIDS RESEARCH (2020)
The gut microbiota confers protection in the CNS against neurodegeneration induced by manganism
Hui Wang et al.
BIOMEDICINE & PHARMACOTHERAPY (2020)
Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway
Xuewu Zhang et al.
IMMUNITY (2020)
Inflammation in Parkinson's Disease: Mechanisms and Therapeutic Implications
Marta Pajares et al.
CELLS (2020)
The gut microbiota attenuate neuroinflammation in manganese exposure by inhibiting cerebral NLRP3 inflammasome
Hui Wang et al.
BIOMEDICINE & PHARMACOTHERAPY (2020)
Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy
Mengze Lv et al.
CELL RESEARCH (2020)
Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease
Simon Dujardin et al.
NATURE MEDICINE (2020)
Photosensitizer-Modified MnO2 Nanoparticles to Enhance Photodynamic Treatment of Abscesses and Boost Immune Protection for Treated Mice
Chenya Wang et al.
SMALL (2020)
cGAS-STING pathway in cancer biotherapy
Yang Wang et al.
MOLECULAR CANCER (2020)
KAT5 acetylates cGAS to promote innate immune response to DNA virus
Ze-Min Song et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Mn2+ Directly Activates cGAS and Structural Analysis Suggests Mn2+ Induces a Noncanonical Catalytic Synthesis of 2′3′-cGAMP
Zhen Zhao et al.
CELL REPORTS (2020)
Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms
Ivan Nyarko-Danquah et al.
MOLECULES (2020)
Jean Rodier: History of Manganism in Morocco
C. Hicham et al.
NEUROTOXICOLOGY (2020)
Autophagy induction via STING trafficking is a primordial function of the cGAS pathway
Xiang Gui et al.
NATURE (2019)
Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP
Guijun Shang et al.
NATURE (2019)
cGAS in action: Expanding roles in immunity and inflammation
Andrea Ablasser et al.
SCIENCE (2019)
Neuro-inflammation and anti-inflammatory treatment options for Alzheimer's disease
Tomris Ozben et al.
CLINICAL BIOCHEMISTRY (2019)
A STING to inflammation and autoimmunity
Vijay Kumar
JOURNAL OF LEUKOCYTE BIOLOGY (2019)
DNA sensing by the cGAS-STING pathway in health and disease
Mona Motwani et al.
NATURE REVIEWS GENETICS (2019)
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
Justin M. Long et al.
CELL (2019)
NLRP3 inflammasome activation drives tau pathology
Christina Ising et al.
NATURE (2019)
The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum
Sonal Srikanth et al.
NATURE IMMUNOLOGY (2019)
Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells
Souvarish Sarkar et al.
SCIENCE SIGNALING (2019)
Higher Hippocampal Mean Diffusivity Values in Asymptomatic Welders
Eun-Young Lee et al.
TOXICOLOGICAL SCIENCES (2019)
Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo
Ilie-Cosmin Stancu et al.
ACTA NEUROPATHOLOGICA (2019)
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
Karen V. Swanson et al.
NATURE REVIEWS IMMUNOLOGY (2019)
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration
Nagaraj Kerur et al.
NATURE MEDICINE (2018)
Role of LRRK2 in manganese-induced neuroinflammation and microglial autophagy
Jiayan Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses
Chenguang Wang et al.
IMMUNITY (2018)
Biological approaches to tackle heavy metal pollution: A survey of literature
Jaya Mary Jacob et al.
JOURNAL OF ENVIRONMENTAL MANAGEMENT (2018)
Targeting the NLRP3 inflammasome in inflammatory diseases
Matthew S. J. Mangan et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Thalamic GABA levels and occupational manganese neurotoxicity: Association with exposure levels and brain MRI
Ruoyun E. Ma et al.
NEUROTOXICOLOGY (2018)
Manganese exposure facilitates microglial JAK2-STAT3 signaling and consequent secretion of TNF-α and IL-1β to promote neuronal death
Lifeng Yin et al.
NEUROTOXICOLOGY (2018)
Welding-related brain and functional changes in welders with chronic and low-level exposure
Eun-Young Lee et al.
NEUROTOXICOLOGY (2018)
STING-dependent translation inhibition restricts RNA virus replication
Kate M. Franz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
DNA-induced liquid phase condensation of cGAS activates innate immune signaling
Mingjian Du et al.
SCIENCE (2018)
Functional and structural damage of neurons by innate immune mechanisms during neurodegeneration
Christina Ising et al.
CELL DEATH & DISEASE (2018)
Inflammasome signalling in brain function and neurodegenerative disease
Michael T. Heneka et al.
NATURE REVIEWS NEUROSCIENCE (2018)
Mn Inhibits GSH Synthesis via Downregulation of Neuronal EAAC1 and Astrocytic xCT to Cause Oxidative Damage in the Striatum of Mice
Xinxin Yang et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
Melatonin Attenuates Manganese and Lipopolysaccharide-Induced Inflammatory Activation of BV2 Microglia
Euteum Park et al.
NEUROCHEMICAL RESEARCH (2017)
The Complement Anaphylatoxins C5a and C3a Suppress IFN-β Production in Response to Listeria monocytogenes by Inhibition of the Cyclic Dinucleotide-Activated Cytosolic Surveillance Pathway
Stacey L. Mueller-Ortiz et al.
JOURNAL OF IMMUNOLOGY (2017)
Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity
Kelly S. Kirkley et al.
JOURNAL OF NEUROINFLAMMATION (2017)
Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease
Carmen Venegas et al.
NATURE (2017)
cGAS is essential for the antitumor effect of immune checkpoint blockade
Hua Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
A New Strategy for Heavy Metal Polluted Environments: A Review of Microbial Biosorbents
Ayansina Segun Ayangbenro et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2017)
The role of NLRP3-CASP1 in inflammasome-mediated neuroinflammation and autophagy dysfunction in manganese-induced, hippocampal-dependent impairment of learning and memory ability
Diya Wang et al.
AUTOPHAGY (2017)
The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3
Moritz M. Gaidt et al.
CELL (2017)
Manganese neurotoxicity: behavioral disorders associated with dysfunctions in the basal ganglia and neurochemical transmission
Safa Bouabid et al.
JOURNAL OF NEUROCHEMISTRY (2016)
Zinc and immunity: An essential interrelation
Maria Maares et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2016)
Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue
Virginia Castiglia et al.
CELL HOST & MICROBE (2016)
The cGAS-STING Defense Pathway and Its Counteraction by Viruses
Zhe Ma et al.
CELL HOST & MICROBE (2016)
The role of cGAS in innate immunity and beyond
Andrea Ablasser et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2016)
Role of neuroinflammation in neurodegenerative diseases
Wei-Wei Chen et al.
MOLECULAR MEDICINE REPORTS (2016)
Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing
Qi Chen et al.
NATURE IMMUNOLOGY (2016)
Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS
Line S. Reinert et al.
NATURE COMMUNICATIONS (2016)
Manganese Is Essential for Neuronal Health
Kyle J. Horning et al.
ANNUAL REVIEW OF NUTRITION, VOL 35 (2015)
Activation of the NLRP3/caspase-1 inflammasome in human dental pulp tissue and human dental pulp fibroblasts
Wenkai Jiang et al.
CELL AND TISSUE RESEARCH (2015)
STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease
Nicole Dobbs et al.
CELL HOST & MICROBE (2015)
Effects of chronic manganese exposure on the learning and memory of rats by observing the changes in the hippocampal cAMP signaling pathway
Guiqiang Liang et al.
FOOD AND CHEMICAL TOXICOLOGY (2015)
Inflammasomes: mechanism of action, role in disease, and therapeutics
Haitao Guo et al.
NATURE MEDICINE (2015)
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
Siqi Liu et al.
SCIENCE (2015)
The STING pathway and the T cell-inflamed tumor microenvironment
Seng-Ryong Woo et al.
TRENDS IN IMMUNOLOGY (2015)
Manganese-Induced Parkinsonism and Parkinson's Disease: Shared and Distinguishable Features
Gunnar F. Kwakye et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2015)
Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production
Michael J. White et al.
CELL (2014)
Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA
Anthony Rongvaux et al.
CELL (2014)
STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
Seng-Ryong Woo et al.
IMMUNITY (2014)
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
Liufu Deng et al.
IMMUNITY (2014)
Activation of the STING Adaptor Attenuates Experimental Autoimmune Encephalitis
Henrique Lemos et al.
JOURNAL OF IMMUNOLOGY (2014)
The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling
Xin Cai et al.
MOLECULAR CELL (2014)
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
Bernardo S. Franklin et al.
NATURE IMMUNOLOGY (2014)
Environmental manganese compounds accumulate as Mn(II) within the Golgi apparatus of dopamine cells: relationship between speciation, subcellular distribution, and cytotoxicity
Asuncion Carmona et al.
METALLOMICS (2014)
Exploring Cross-Talk Between Oxidative Damage and Excitotoxicity and the Effects of Riluzole in the Rat Cortex After Exposure to Methylmercury
Yu Deng et al.
NEUROTOXICITY RESEARCH (2014)
Vulnerability of welders to manganese exposure - A neuroimaging study
Long Zaiyang et al.
NEUROTOXICOLOGY (2014)
The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop
Xu Zhang et al.
CELL REPORTS (2014)
Regulation of type I interferon responses
Lionel B. Ivashkiv et al.
NATURE REVIEWS IMMUNOLOGY (2014)
Cyclic [G(2′,5′) pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
Pu Gao et al.
CELL (2013)
Nonoccupational Environmental Exposure to Manganese is Linked to Deficits in Peripheral and Central Olfactory Function
Marco Guarneros et al.
CHEMICAL SENSES (2013)
Manganese neurotoxicity and the role of reactive oxygen species
Ebany J. Martinez-Finley et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization
Xin Li et al.
IMMUNITY (2013)
Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
Xu Zhang et al.
MOLECULAR CELL (2013)
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
Michael T. Heneka et al.
NATURE (2013)
cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
Andrea Ablasser et al.
NATURE (2013)
Structural mechanism of cytosolic DNA sensing by cGAS
Filiz Civril et al.
NATURE (2013)
Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
Jiaxi Wu et al.
SCIENCE (2013)
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
Lijun Sun et al.
SCIENCE (2013)
Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects
Xiao-Dong Li et al.
SCIENCE (2013)
Oxidative stress involvement in manganese-induced alpha-synuclein oligomerization in organotypic brain slice cultures
Bin Xu et al.
TOXICOLOGY (2013)
Innate immune detection of microbial nucleic acids
Claudia Guertler et al.
TRENDS IN MICROBIOLOGY (2013)
Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity
Philip J. Kranzusch et al.
CELL REPORTS (2013)
The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
Elie J. Diner et al.
CELL REPORTS (2013)
Mitochondria, oxidative stress and neurodegeneration
Antonio Federico et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2012)
Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system
Chang Shu et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP
Guijun Shang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Increased risk of parkinsonism associated with welding exposure
Brad A. Racette et al.
NEUROTOXICOLOGY (2012)
Tremor, olfactory and motor changes in Italian adolescents exposed to historical ferro-manganese emission
Roberto G. Lucchini et al.
NEUROTOXICOLOGY (2012)
STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway
Yasuo Tanaka et al.
SCIENCE SIGNALING (2012)
Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity
Huihui Chen et al.
CELL (2011)
Myeloid C-type Lectin Receptors in Pathogen Recognition and Host Defense
Fabiola Osorio et al.
IMMUNITY (2011)
Cytoplasmic DNA innate immune pathways
Glen N. Barber
IMMUNOLOGICAL REVIEWS (2011)
Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative damage and neuronal injury
Dejan Milatovic et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2011)
Pattern Recognition Receptors and Inflammation
Osamu Takeuchi et al.
CELL (2010)
The protective effect of riluzole on manganese caused disruption of glutamate-glutamine cycle in rats
Yu Deng et al.
BRAIN RESEARCH (2009)
The TLR-independent DNA recognition pathway in murine macrophages: Ligand features and molecular signature
Evren Karayel et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
Hiroki Ishikawa et al.
NATURE (2009)
RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate
Andrea Ablasser et al.
NATURE IMMUNOLOGY (2009)
Comprehensive classification of nucleotidyltransferase fold proteins: identification of novel families and their representatives in human
Krzysztof Kuchta et al.
NUCLEIC ACIDS RESEARCH (2009)
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
Tatsuya Saitoh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
Wenxiang Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
Bo Zhong et al.
IMMUNITY (2008)
MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals
Lei Jin et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
Hiroki Ishikawa et al.
NATURE (2008)
Manganese induces oxidative impairment in cultured rat astrocytes
Dejan Milatovic et al.
TOXICOLOGICAL SCIENCES (2007)
Manganese inhalation by rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity
Keith M. Erikson et al.
TOXICOLOGICAL SCIENCES (2007)
Speciation of manganese in cells and mitochondria: A search for the proximal cause of manganese neurotoxicity
Thomas E. Gunter et al.
NEUROTOXICOLOGY (2006)
Translocation of inhaled ultrafine manganese oxide particles to the central nervous system
Alison Elder et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2006)
The transport of manganese across the blood-brain barrier
M Aschner
NEUROTOXICOLOGY (2006)
The diagnosis of manganese-induced parkinsonism
Maria G. Cersosimo et al.
NEUROTOXICOLOGY (2006)
Pathogen recognition and innate immunity
S Akira et al.
CELL (2006)
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
DB Stetson et al.
IMMUNITY (2006)
Manganese dosimetry: Species differences and implications for neurotoxicity
M Aschner et al.
CRITICAL REVIEWS IN TOXICOLOGY (2005)
Role of tau protein in both physiological and pathological conditions
J Avila et al.
PHYSIOLOGICAL REVIEWS (2004)
In vivo trans-synaptic tract tracing from the murine striatum and amygdala utilizing manganese enhanced MRI (MEMRI)
RG Pautler et al.
MAGNETIC RESONANCE IN MEDICINE (2003)
Triggering the interferon antiviral response through an IKK-related pathway
S Sharma et al.
SCIENCE (2003)
IKKε and TBK1 are essential components of the IRF3 signaling pathway
KA Fitzgerald et al.
NATURE IMMUNOLOGY (2003)
Hazards of heavy metal contamination
L Jarup
BRITISH MEDICAL BULLETIN (2003)
Brain manganese concentrations in rats following manganese tetroxide inhalation are unaffected by dietary manganese intake
DC Dorman et al.
NEUROTOXICOLOGY (2002)
分享论文
