4.7 Article

Title: Involvement of unsaturated fatty acid biosynthesis in CRC progression based on in vitro and in silico studies

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Characterization of the fatty acid metabolism in colorectal cancer to guide clinical therapy

Chengsheng Ding et al.

Summary: The study investigated the role of fatty acid metabolism in colorectal cancer (CRC) and established a prognostic risk score model based on fatty acid metabolism-related genes. The model can predict the prognosis of CRC patients and guide effective immunotherapy regimens.

MOLECULAR THERAPY-ONCOLYTICS (2021)

Article Oncology

A global assessment of recent trends in gastrointestinal cancer and lifestyle-associated risk factors

Lili Lu et al.

Summary: Gastrointestinal (GI) cancers exhibit regional differences in incidence, mortality, and prevalence worldwide, with higher mortality rates in developing countries possibly due to inadequate prevention and treatment strategies. The prevalence of GI cancers is positively correlated with national human development indices and lifestyle-associated risk factors, but negatively correlated with hypertension and diabetes.

CANCER COMMUNICATIONS (2021)

Review Oncology

A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis

Tomasz Sawicki et al.

Summary: Colorectal cancer is one of the most common malignant tumors, with increasing incidence and mortality rates each year. Genetic and environmental factors, as well as lifestyle choices, play a significant role in its development. Studying the epidemiology and diagnosis of colorectal cancer is crucial for informing future strategies in disease prevention and control.

CANCERS (2021)

Article Oncology

Macrophage inhibitory cytokine-1 induced by a high-fat diet promotes prostate cancer progression by stimulating tumor-promoting cytokine production from tumor stromal cells

Mingguo Huang et al.

Summary: This study revealed that HFD stimulates PCa cell growth and invasion through upregulation of MIC-1 signaling, leading to increased secretion of interleukins from prostate stromal fibroblasts. Periprostatic adipocytes also play a role in stimulating MIC-1 production and cytokine secretion through adipose lipolysis, potentially contributing to obesity-induced PCa progression.

CANCER COMMUNICATIONS (2021)

Review Oncology

Metabolic regulation in the immune response to cancer

Qi Wu et al.

Summary: Metabolic reprogramming plays a key role in tumor-immune interactions, influencing pro-inflammatory carcinogenic effects and anticancer immune responses. Dysregulated metabolites impact both cancer progression and therapeutic responses. Possible interventions at multiple levels are discussed to enhance the efficacy of immunotherapeutic and conventional approaches in future anticancer treatments.

CANCER COMMUNICATIONS (2021)

Review Gastroenterology & Hepatology

Prevalence and risk factors of colorectal cancer in Asia

Martin C. S. Wong et al.

INTESTINAL RESEARCH (2019)

Review Medicine, Research & Experimental

The expanded role of fatty acid metabolism in cancer: new aspects and targets

Ming Chen et al.

PRECISION CLINICAL MEDICINE (2019)

Letter Medicine, General & Internal

Determining the worldwide prevalence of obesity

John J. Reilly et al.

LANCET (2018)

Review Cell Biology

Cellular Fatty Acid Metabolism and Cancer

Erin Currie et al.

CELL METABOLISM (2013)

Article Gastroenterology & Hepatology

Obesity and colorectal cancer

Marc Bardou et al.

Editorial Material Nutrition & Dietetics

Linoleic Acid

Jay Whelan et al.

ADVANCES IN NUTRITION (2013)

Article Nutrition & Dietetics

Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century

Tanya L. Blasbalg et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2011)

Review Pathology

Molecular Genetics of Colorectal Cancer

Eric R. Fearon

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 6 (2011)

Article Biochemistry & Molecular Biology

Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction

Xiaofeng Lu et al.

LIPIDS IN HEALTH AND DISEASE (2010)

Article Biochemistry & Molecular Biology

Impact of linoleic acid intake on arachidonic acid formation and eicosanoid biosynthesis in humans

O. Adam et al.

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2008)

Article Biochemistry & Molecular Biology

The health implications of changing linoleic acid intakes

Jay Whelan

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2008)

Review Medicine, Research & Experimental

The Role of PPAR-gamma and Its Interaction with COX-2 in Pancreatic Cancer

Guido Eibl

PPAR RESEARCH (2008)

Review Medicine, Research & Experimental

The Roles of Dietary PPAR gamma Ligands for Metastasis in Colorectal Cancer

Hiroki Kuniyasu

PPAR RESEARCH (2008)

Article Nutrition & Dietetics

γ-linolenate reduces weight regain in formerly obese humans

Marie A. Schirmer et al.

JOURNAL OF NUTRITION (2007)

Review Biochemistry & Molecular Biology

Obesity and colorectal cancer: epidemiology, mechanisms and candidate genes

MJ Gunter et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2006)

Review Biochemistry & Molecular Biology

Polyunsaturated fatty acid synthesis: what will they think of next?

JG Wallis et al.

TRENDS IN BIOCHEMICAL SCIENCES (2002)