Metabolite profiling analysis of hepatitis B virus-induced liver cirrhosis patients with minimal hepatic encephalopathy using gas chromatography-time-of-flight mass spectrometry and ultra-performance liquid chromatography-quadrupole-time-of-flight ma...

Article Pediatrics

Alterations of gut microbiota and serum bile acids are associated with parenteral nutrition-associated liver disease

Nan Wang et al.

Summary: This study found changes in the taxonomic and functional composition of gut microbiota in a rat model of PNALD, leading to an increase in secondary bile acid production.

JOURNAL OF PEDIATRIC SURGERY (2021)

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Article Gastroenterology & Hepatology

Hepatic NFAT signaling regulates the expression of inflammatory cytokines in cholestasis

Shi-Ying Cai et al.

Summary: NFAT is essential in regulating cytokine expression in cholestatic liver injury, and inhibiting NFAT activation could potentially alleviate cholestasis-induced liver damage.

JOURNAL OF HEPATOLOGY (2021)

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Article Mathematical & Computational Biology

Feature selection using distributions of orthogonal PLS regression vectors in spectral data

Geonseok Lee et al.

Summary: Feature selection is crucial in chemometric data analysis to produce predictive models. This paper introduces a method of feature selection through orthogonal PLS regression, which combines signal correction with PLS, to generate empirical distributions and examine the significance of input features on the response variable Y. The performance of this method is demonstrated using simulation studies and real-life data such as NIR spectra and mass spectrometry data.

BIODATA MINING (2021)

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Article Chemistry, Multidisciplinary

LC/MS-Based Global Metabolomic Identification of Serum Biomarkers Differentiating Hepatocellular Carcinoma from Chronic Hepatitis B and Liver Cirrhosis

Hong Y. Pan et al.

Summary: Chronic hepatitis B virus infection is a primary risk factor for hepatocellular carcinoma development. This study used LC-MS to analyze serum metabolic profiles of CHB, LC, and HCC patients, identifying metabolites that change with liver disease progression. Certain metabolites, such as TCA and eicosapentaenoic acid, were found to have diagnostic performance with liver disease progression and are correlated with AFP levels and age.

ACS OMEGA (2021)

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Review Chemistry, Physical

Covariance NMR: Theoretical concerns, practical considerations, contemporary applications and related techniques

David A. Snyder

Summary: Covariance NMR techniques are continuously expanding and being applied in areas such as reconstructing pure shift NMR spectra and processing non-uniformly sampled data. This review discusses theoretical and practical considerations for direct and indirect covariance NMR techniques and outlines recent additions to the covariance NMR family.

PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (2021)

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Article Chemistry, Medicinal

Expert insights: The potential role of the gut microbiome-bile acid-brain axis in the development and progression of Alzheimer's disease and hepatic encephalopathy

Wei Jia et al.

MEDICINAL RESEARCH REVIEWS (2020)

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Article Gastroenterology & Hepatology

Prospective evaluation of the impact of covert hepatic encephalopathy on quality of life and sleep in cirrhotic patients

C. Labenz et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2018)

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Article Toxicology

Urinary Time- or Dose-Dependent Metabolic Biomarkers of Aristolochic Acid-Induced Nephrotoxicity in Rats

Xueqing Hu et al.

TOXICOLOGICAL SCIENCES (2017)

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Article Biochemistry & Molecular Biology

Recommendations for Improving Identification and Quantification in Non-Targeted, GC-MS-Based Metabolomic Profiling of Human Plasma

Hanghang Wang et al.

METABOLITES (2017)

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Review Medicine, General & Internal

Interactions between Bacteria and Bile Salts in the Gastrointestinal and Hepatobiliary Tracts

Veronica Urdaneta et al.

FRONTIERS IN MEDICINE (2017)

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Article Gastroenterology & Hepatology

Evaluation of cognitivity, proinflammatory cytokines, and brain magnetic resonance imaging in minimal hepatic encephalopathy induced by cirrhosis and extrahepatic portal vein obstruction

Santosh K. Yadav et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2016)

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Article Multidisciplinary Sciences

Detecting Minimal Hepatic Encephalopathy in an Endemic Country for Hepatitis B: The Role of Psychometrics and Serum IL-6

Chia-Fen Tsai et al.

PLOS ONE (2015)

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Article Oncology

A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential

Yunping Qiu et al.

CLINICAL CANCER RESEARCH (2014)

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Article Biochemical Research Methods

Global gas chromatography/time-of-flight mass spectrometry (GC/TOFMS)-based metabonomic profiling of lyophilized human feces

Lee Cheng Phua et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2013)

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Article Biochemical Research Methods

Metabonomics Identifies Serum Metabolite Markers of Colorectal Cancer

Binbin Tan et al.

JOURNAL OF PROTEOME RESEARCH (2013)

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Article Gastroenterology & Hepatology

Serum nitrotyrosine and psychometric tests as indicators of impaired fitness to drive in cirrhotic patients with minimal hepatic encephalopathy

Vicente Felipo et al.

LIVER INTERNATIONAL (2013)

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Article Physiology

Bile Acid Metabolism and Signaling

John Y. L. Chiang

COMPREHENSIVE PHYSIOLOGY (2013)

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Article Gastroenterology & Hepatology

Bile Acid Is a Host Factor That Regulates the Composition of the Cecal Microbiota in Rats

K. B. M. Saiful Islam et al.

GASTROENTEROLOGY (2011)

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Article Chemistry, Analytical

Metabolite profiling of hemodialysate using gas chromatography time-of-flight mass spectrometry

Xin Qi et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2011)

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Article Biochemical Research Methods

An Automated Data Analysis Pipeline for GC-TOF-MS Metabonomics Studies

Wenxin Jiang et al.

JOURNAL OF PROTEOME RESEARCH (2010)

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Article Biochemistry & Molecular Biology

A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry

Peiyuan Yin et al.

MOLECULAR BIOSYSTEMS (2009)

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Letter Biotechnology & Applied Microbiology

NCBI Peptidome: a new public repository for mass spectrometry peptide identifications

Douglas J. Slotta et al.

NATURE BIOTECHNOLOGY (2009)

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Article Chemistry, Analytical

Orthogonal projections to latent structures discriminant analysis modeling on in situ FT-IR spectral imaging of liver tissue for identifying sources of variability

Hans Stenlund et al.

ANALYTICAL CHEMISTRY (2008)

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Article Chemistry, Analytical

Ultra-performance LC/TOF MS analysis of medicinal Panax herbs for metabolomic research

Guoxiang Xie et al.

JOURNAL OF SEPARATION SCIENCE (2008)

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Metabolite profiling analysis of hepatitis B virus-induced liver cirrhosis patients with minimal hepatic encephalopathy using gas chromatography-time-of-flight mass spectrometry and ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry

相关参考文献

Alterations of gut microbiota and serum bile acids are associated with parenteral nutrition-associated liver disease

Hepatic NFAT signaling regulates the expression of inflammatory cytokines in cholestasis

Feature selection using distributions of orthogonal PLS regression vectors in spectral data

LC/MS-Based Global Metabolomic Identification of Serum Biomarkers Differentiating Hepatocellular Carcinoma from Chronic Hepatitis B and Liver Cirrhosis

Covariance NMR: Theoretical concerns, practical considerations, contemporary applications and related techniques

Expert insights: The potential role of the gut microbiome-bile acid-brain axis in the development and progression of Alzheimer's disease and hepatic encephalopathy

Prospective evaluation of the impact of covert hepatic encephalopathy on quality of life and sleep in cirrhotic patients

Urinary Time- or Dose-Dependent Metabolic Biomarkers of Aristolochic Acid-Induced Nephrotoxicity in Rats

Recommendations for Improving Identification and Quantification in Non-Targeted, GC-MS-Based Metabolomic Profiling of Human Plasma

Interactions between Bacteria and Bile Salts in the Gastrointestinal and Hepatobiliary Tracts

Evaluation of cognitivity, proinflammatory cytokines, and brain magnetic resonance imaging in minimal hepatic encephalopathy induced by cirrhosis and extrahepatic portal vein obstruction

Detecting Minimal Hepatic Encephalopathy in an Endemic Country for Hepatitis B: The Role of Psychometrics and Serum IL-6

A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential

Global gas chromatography/time-of-flight mass spectrometry (GC/TOFMS)-based metabonomic profiling of lyophilized human feces

Metabonomics Identifies Serum Metabolite Markers of Colorectal Cancer

Serum nitrotyrosine and psychometric tests as indicators of impaired fitness to drive in cirrhotic patients with minimal hepatic encephalopathy

Bile Acid Metabolism and Signaling

Bile Acid Is a Host Factor That Regulates the Composition of the Cecal Microbiota in Rats

Metabolite profiling of hemodialysate using gas chromatography time-of-flight mass spectrometry

An Automated Data Analysis Pipeline for GC-TOF-MS Metabonomics Studies

A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry

NCBI Peptidome: a new public repository for mass spectrometry peptide identifications

Orthogonal projections to latent structures discriminant analysis modeling on in situ FT-IR spectral imaging of liver tissue for identifying sources of variability

Ultra-performance LC/TOF MS analysis of medicinal Panax herbs for metabolomic research

Metabolite profiling analysis of hepatitis B virus-induced liver cirrhosis patients with minimal hepatic encephalopathy using gas chromatography-time-of-flight mass spectrometry and ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry

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