CGV: Cancer Genome Viewer, a web service for integrative cancer genome and pharmacogenomic data analysis

Motivation: Multi-omic profiling data, such as The Cancer Genome Atlas and pharmacogenomic data, facilitate research into cancer mechanisms and drug development. However, it is not easy for researchers to connect, integrate and analyze huge and heterogeneous data, which is a major obstacle to the utilization of cancer genomic data. Results: We developed Cancer Genome Viewer (CGV), a user-friendly web service that provides functions to integrate and visualize cancer genome data and pharmacogenomic data. Users can easily select and customize the samples to be analyzed with the pre-defined selection options for patients' clinic-pathological features from multiple datasets. Using the customized dataset, users can perform subsequent data analyses comprehensively, including gene set analysis, clustering or survival analysis. CGV also provides pre-calculated drug response scores from pharmacogenomic data, which may facilitate the discovery of new cancer targets and therapeutics.

Automated summary

Researchers can utilize the user-friendly web service Cancer Genome Viewer (CGV) to connect, integrate, and analyze cancer genomic data and pharmacogenomic data. They can customize the selection of samples to be analyzed using pre-defined options from multiple datasets. CGV also provides pre-calculated drug response scores, aiding in the discovery of new cancer targets and therapeutics.