相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Telomere dysfunction in ageing and age-related diseases
Francesca Rossiello et al.
NATURE CELL BIOLOGY (2022)
AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models
Mihaly Varadi et al.
NUCLEIC ACIDS RESEARCH (2022)
Crystal structure of progeria mutant S143F lamin A/C reveals increased hydrophobicity driving nuclear deformation
Jinsook Ahn et al.
COMMUNICATIONS BIOLOGY (2022)
Farnesyltransferase inhibition in HGPS
Tom Misteli
CELL (2021)
FDA approves first EGFR exon 20 targeted kinase inhibitor
Asher Mullard
NATURE REVIEWS DRUG DISCOVERY (2021)
Lamin post-translational modifications: emerging toggles of nuclear organization and function
Laura A. Murray-Nerger et al.
TRENDS IN BIOCHEMICAL SCIENCES (2021)
Beta-strand-mediated dimeric formation of the Ig-like domains of human lamin A/C and B1
Jinsook Ahn et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)
Highly accurate protein structure prediction with AlphaFold
John Jumper et al.
NATURE (2021)
Premature aging syndromes: From patients to mechanism
Mattheus Xing Rong Foo et al.
JOURNAL OF DERMATOLOGICAL SCIENCE (2019)
Oxidative stress, aging, and diseases
Ilaria Liguori et al.
CLINICAL INTERVENTIONS IN AGING (2018)
Selenium and Selenocysteine in Protein Chemistry
Reem Mousa et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Interruption of progerin-lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype
Su-Jin Lee et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation
S. Blondel et al.
CELL DEATH & DISEASE (2016)
Genetics of aging, progeria and lamin disorders
Shrestha Ghosh et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2014)
Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective
Pierre Cau et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)
Use of knowledge-based restraints in phenix.refine to improve macromolecular refinement at low resolution
Jeffrey J. Headd et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2012)
Overview of the CCP4 suite and current developments
Martyn D. Winn et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2011)
Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect
Valerie L. R. M. Verstraeten et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Mitochondrial dysfunction as a cause of ageing
A. Trifunovic et al.
JOURNAL OF INTERNAL MEDICINE (2008)
A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells
Kan Cao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Lamin A-dependent nuclear defects in human aging
P Scaffidi et al.
SCIENCE (2006)
Farnesyl transferase inhibitors
AD Basso et al.
JOURNAL OF LIPID RESEARCH (2006)
Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome
BC Capell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Coot:: model-building tools for molecular graphics
P Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome
RD Goldman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Lamin A truncation in Hutchinson-Gilford progeria
A De Sandre-Giovannoli et al.
SCIENCE (2003)
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome
M Eriksson et al.
NATURE (2003)