Heart rate variability (HRV): Checklist for observational and experimental studies

Article Clinical Neurology

Complement activation mainly mediates the association of heart rate variability and cognitive impairment in adults with obstructive sleep apnea without dementia

Song Xue et al.

Summary: This study aimed to analyze the role of complement activation, Alzheimer's disease biomarkers, and white matter hyperintensity in modulating the association of heart rate variability (HRV) with cognitive performance in obstructive sleep apnea patients. The findings suggest that OSA patients with mild cognitive impairment have lower HRV indices and complement activation, AD biomarkers, and WMH may partially mediate and interact with the influence of HRV on cognitive impairment.

SLEEP (2023)

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Review Cell Biology

Heart rate variability in relation to cognition and behavior in neurodegenerative diseases: A systematic review and meta-analysis

Kathy Y. Liu et al.

Summary: The review found that higher heart rate variability (HRV) in patients with neurodegenerative diseases was associated with better cognitive and behavioral scores. This relationship was not influenced by age or cognitive status, suggesting that HRV may be a marker of self-regulatory processes in these conditions. Further research is needed to explore this association with neuropsychiatric symptoms and neuroimaging methods.

AGEING RESEARCH REVIEWS (2022)

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Review Psychiatry

Heart rate variability in patients with dementia or neurocognitive disorders: A systematic review and meta-analysis

Ying-Chih Cheng et al.

Summary: Heart rate variability is a useful measure for evaluating neurological and psychiatric disorders like dementia. Patients with dementia, especially those with Lewy body dementia and mild cognitive impairment, show lower parasympathetic activity compared to healthy controls. The meta-analysis results suggest that gender may influence the effect size of heart rate variability in dementia patients.

AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2022)

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Article Physiology

Heart rate variability as a function of menopausal status, menstrual cycle phase, and estradiol level

Sharanya Ramesh et al.

Summary: Low estradiol status is associated with increased cardiovascular risk. Menopausal status and the high estradiol phase in premenopausal women are associated with reduced heart rate variability (HRV), a marker of cardiovascular risk. Understanding the role of estradiol in modulating cardiac autonomic tone may help guide risk reduction strategies in women.

PHYSIOLOGICAL REPORTS (2022)

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Article Immunology

Psychiatric manifestations of autoimmune encephalitis

Hannah Ford et al.

Summary: Autoimmune encephalitis is recognized as a cause of psychiatric symptoms, with a wide range of manifestations that may not necessarily be associated with neurological features. Patients generally respond to immunotherapy, but diagnosis can be challenging due to phenotypic heterogeneity. Understanding potential immunopathological indicators is important for elucidating the mechanisms underlying psychiatric manifestations.

AUTOIMMUNITY REVIEWS (2022)

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Article Orthopedics