期刊
JOURNAL OF HAZARDOUS MATERIALS
卷 317, 期 -, 页码 552-562出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jhazmat.2016.05.083
关键词
Lung bioaccessibility; Gastric bioaccessibility; Exposure assessment; Metal; Particle size
资金
- ANR (ToxBol project)
- ANR (COMIBOL project)
- INSU-Ec2co (Aerobol project)
- Labex OSUG@2020 [ANR10 LABX56]
Refined exposure assessments were realized for children, 7-9 yrs, in the mining/smelting city of Oruro, Bolivia. Aerosols (PM>2.5, PM1-2.5, PM0.4-1 and PM0.5) and dust (separated in different particle size fractions: 2000-200 mu m, 200-50 mu m, 50-20 mu m, 20-2 mu m and <2 mu m) were sampled on football fields highly frequented by children in both the mining and smelting areas. Trace element concentrations (Ag, As, Cd, Cu, Pb, Sb, Sn and Zn) in each size fraction of dust and aerosols, lung bioaccessibility of metals in aerosols, and gastric bioaccessibility of metals in dust were measured. Exposure was assessed considering actual external exposure (i.e. exposure pathways: metals inhaled and ingested) and simulated internal exposure (i.e., complex estimation using gastric and lung bioaccessibility, deposition and clearance of particles in lungs). Significant differences between external and simulated internal exposure were attributed to dissemblances in gastric and lung bioaccessibilities, as well as metal distribution within particle size range, revealing the importance of both parameters in exposure assessment. (C) 2016 Elsevier B.V. All rights reserved.
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