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Article
Endocrinology & Metabolism
Evanthia Giannoula et al.
Summary: This article summarizes the adjustments made by nuclear thyroidology during the COVID-19 pandemic to prevent the spread of the virus while maintaining the quality and safety of the services provided.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2022)
Review
Obstetrics & Gynecology
Fei Chen et al.
Summary: The COVID-19 pandemic has led to the rapid development and approval of multiple vaccines, including mRNA vaccines, which are considered ideal candidates. However, concerns about safety and efficacy have been raised, particularly regarding fertility. While current evidence is limited, studies suggest that COVID-19 mRNA vaccines do not have negative effects on fertility, even in pregnant women. Additional research, especially larger population-based studies, are needed to further assess the impact of vaccination on reproduction.
HUMAN REPRODUCTION
(2022)
Article
Endocrinology & Metabolism
Seda Hanife Oguz et al.
Summary: This study presents a long-term clinical follow-up of patients with SARS-CoV-2 vaccine-induced subacute thyroiditis (SAT) and Graves' disease (GD), and provides data on the safety of revaccinations. The results suggest that revaccinations appear to be safe in patients with SARS-CoV-2 vaccine-induced SAT cases, but more evidence is needed regarding SARS-CoV-2 vaccine-induced GD.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Review
Endocrinology & Metabolism
Harsha Anuruddhika Dissanayake et al.
Summary: Multiple observational studies involving nearly 2 million adults suggest that vitamin D deficiency/insufficiency increases susceptibility to COVID-19 and severe COVID-19, although with a high risk of bias and heterogeneity. Association with mortality was less robust. Heterogeneity in RCTs precluded their meta-analysis.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Review
Medicine, General & Internal
Nasrin Amiri-Dashatan et al.
Summary: This study reevaluated the association between cortisol level and severity of COVID-19 infection and found that higher cortisol levels are associated with severe COVID-19. This finding could be useful in identifying patients with poor prognosis at early stages of the disease, although age and sex may influence cortisol levels.
JOURNAL OF INVESTIGATIVE MEDICINE
(2022)
Article
Urology & Nephrology
R. Clayton Edenfield et al.
Summary: Early studies have suggested that SARS-CoV-2 might access the reproductive system and affect male fertility. Research on the mechanisms of infection of reproductive cells and the potential for testicular dysfunction in patients who have had COVID-19 is crucial for understanding the impact of the virus on male fertility.
NATURE REVIEWS UROLOGY
(2022)
Article
Multidisciplinary Sciences
Valeria Garcia-Flores et al.
Summary: This study presents the maternal-fetal immune responses triggered by SARS-CoV-2 infection during pregnancy and highlights the rarity of placental infection. A T-cell dominant inflammatory response is observed at the maternal-fetal interface, but the virus remains undetectable in the placenta while triggering specific immune responses in the neonatal circulation.
NATURE COMMUNICATIONS
(2022)
Letter
Endocrinology & Metabolism
Waldemar Kanczkowski et al.
LANCET DIABETES & ENDOCRINOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Heather S. Lipkind et al.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2022)
Article
Endocrinology & Metabolism
Yiru Chen et al.
Summary: There is an association between abnormal thyroid-related hormones in COVID-19 patients and the severity of the disease and mortality.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Luigi di Filippo et al.
Summary: COVID-19 patients may experience various endocrine manifestations, such as hypocalcemia, vertebral fractures, and vitamin D deficiency, which could negatively impact disease severity, inflammatory response, thrombotic markers, and mortality. Prompt assessment, monitoring, and calcium replacement are recommended to prevent severe complications.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
(2022)
Article
Endocrinology & Metabolism
Seda Hanife Oguz et al.
Summary: COVID-19 severe cases are associated with mortality due to acute respiratory distress syndrome, cytokine storm, and thrombotic events. While all contributing factors are not yet clear, older age remains a major risk factor. Age-related immune and hormonal changes play a significant role in the severity of COVID-19.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
(2022)
Review
Obstetrics & Gynecology
Denise J. Jamieson et al.
Summary: Physiological, mechanical, and immunologic changes in pregnancy may affect susceptibility to and severity of COVID-19. Pregnancy is a risk factor for severe disease, with pregnant individuals more likely to experience adverse outcomes. Intrauterine transmission of SARS-CoV-2 is rare, possibly due to low viral levels and reduced expression of necessary receptors in the placenta. COVID-19 and its impact on healthcare systems have also had negative effects on pregnancy outcomes.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Review
Medicine, Research & Experimental
Awadhesh Kumar Singh et al.
Summary: The prevalence of diabetes in COVID-19 varies worldwide, with evidence suggesting that individuals with diabetes, especially those with poor glycemic control, have a higher severity and mortality rate. While new-onset hyperglycemia and diabetes have been observed in COVID-19 patients, there is no conclusive evidence of direct tropism of SARS-CoV-2 on pancreatic islet cells. Approved oral antidiabetic agents appear to be safe for individuals with type 2 diabetes who have COVID-19, but there is currently a lack of conclusive data regarding mortality benefits.
ANNUAL REVIEW OF MEDICINE
(2022)
Article
Endocrinology & Metabolism
Rachel Wong et al.
Summary: In a large multicenter cohort of T2D patients with COVID-19 infection in the US, a higher HbA(1c) level was found to be associated with an increased risk of hospitalization. The risk of death and invasive ventilation also increased but plateaued at different levels of glycemic control. There was no significant difference in length of stay across different HbA(1c) levels.
Article
Endocrinology & Metabolism
Iza F. R. Machado et al.
Summary: COVID-19 may cause bilateral adrenal infarction, which is associated with positive antiphospholipid antibodies. Therefore, patients with positive antiphospholipid antibodies should be closely monitored for symptoms or signs of acute adrenal insufficiency during COVID-19.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Multidisciplinary Sciences
Thomas Yates et al.
Summary: Obesity and ethnicity have been found to be risk factors for COVID-19 outcomes. This study reveals that the association between body mass index (BMI) and COVID-19 mortality is stronger in ethnic minority groups, suggesting that the ethnic risk of COVID-19 mortality depends on BMI.
NATURE COMMUNICATIONS
(2022)
Article
Andrology
Andrea Salonia et al.
Summary: Although total testosterone levels increased over time after COVID-19, more than 50% of men who recovered from the disease still had circulating testosterone levels suggestive for a condition of hypogonadism at 7-month follow-up. In as many as 10% of cases, testosterone levels even further decreased. Of clinical relevance, the higher the burden of comorbid conditions at presentation, the lower the probability of testosterone levels recovery over time.
Article
Endocrinology & Metabolism
J. Oristrell et al.
Summary: In this large population-based study, it was observed that supplementation with cholecalciferol or calcifediol leading to serum 25OHD levels >= 30 ng/ml was associated with better COVID-19 outcomes.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2022)
Editorial Material
Endocrinology & Metabolism
Nicole Bechmann et al.
Summary: Current evidence shows that COVID-19 severity and mortality are higher in men compared to women, while women may be at a higher risk of reinfection and long-term COVID-19 development. Differences between sexes have also been observed in other infectious diseases and vaccine responses. This could be explained by sex-specific expression patterns of proteins involved in virus binding and entry, as well as divergent reactions of the immune and endocrine systems to acute stress. Understanding the role of sex hormones, comorbidities, and sex chromosome complement in COVID-19 could have implications for disease treatment, public health measures, and follow-up of patients predisposed to long COVID. Considering sex differences in future pandemic surveillance and COVID-19 patient treatment may lead to better disease stratification and improved outcomes.
LANCET DIABETES & ENDOCRINOLOGY
(2022)
Article
Immunology
Lindsay Kim et al.
Summary: This study identified factors associated with severe outcomes among adults hospitalized with COVID-19, including age, sex, comorbidities like obesity, immunosuppression, and diabetes. Older age, male gender, and certain underlying conditions were independently linked to increased risk of ICU admission and in-hospital mortality.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Pierre Leyendecker et al.
Summary: Acute adrenal infarction is frequent in severe COVID-19 patients and may be a sign of poor prognosis, with higher ICU admission rates and longer hospital stays but similar mortality rates compared to patients without adrenal infarction.
EUROPEAN RADIOLOGY
(2021)
Review
Immunology
Effat Alemzadeh et al.
Summary: This study found a significant association between hypocalcemia and severity of disease, mortality, hospitalization days, and admission to the intensive care unit in COVID-19 patients. Additionally, low serum calcium levels were found to be directly related to increasing D-dimer levels and decreasing lymphocyte counts. Consideration of serum calcium levels in initial assessments is recommended for determining disease severity.
IMMUNITY INFLAMMATION AND DISEASE
(2021)
Article
Endocrinology & Metabolism
Yanbin Du et al.
Summary: This study examined the association between BMI and COVID-19 severity and mortality through a meta-analysis of 16 observational studies involving 109,881 patients. The findings showed a linear dose-response relationship between BMI and critical COVID-19 and mortality, with patients with BMI > 30 kg/m(2) at higher risk. Age and obesity were also found to impact this association.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2021)
Review
Microbiology
Ben Hu et al.
Summary: This review summarizes the research progress on SARS-CoV-2 and COVID-19, including virology characteristics, pathogenesis, and recent advances in treatment methods. Furthermore, it discusses in detail the potential wildlife hosts and zoonotic origin of this emerging virus.
NATURE REVIEWS MICROBIOLOGY
(2021)
Article
Obstetrics & Gynecology
Kezhen Li et al.
Summary: While COVID-19 infection may affect menstrual volume and cycle length in women of child-bearing age, the average levels of sex hormones and ovarian reserve did not show significant changes. The changes observed in menstruation may be temporary and reversible, potentially attributed to transient suppression of ovarian function.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Letter
Medicine, General & Internal
Jonathan W. Cunningham et al.
JAMA INTERNAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Nicholas S. Hendren et al.
Summary: This study found that obese patients are more likely to be hospitalized with COVID-19, and are at higher risk of in-hospital death or mechanical ventilation, particularly if young (age <= 50 years). Additionally, obese patients are also at higher risk for venous thromboembolism and dialysis. These observations support clear public health messaging and rigorous adherence to COVID-19 prevention strategies in all obese individuals regardless of age.
Article
Endocrinology & Metabolism
Cihan Atila et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Mirjam Christ-Crain et al.
Summary: COVID-19 pandemic has shifted medical consultations to virtual platforms, impacting patients with DI and hyponatraemia. Recommendations include delaying desmopressin dose for DI patients, monitoring body weight, and cautious administration of IV fluid replacement in severe COVID-19 cases to avoid pulmonary edema risk.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2021)
Review
Endocrinology & Metabolism
Norbert Stefan et al.
Summary: Obesity and impaired metabolic health are established risk factors for NCDs such as type 2 diabetes mellitus, cardiovascular disease, neurodegenerative diseases, cancer, and MAFLD, and have been linked to an increased risk of severe COVID-19. Specifically, visceral obesity and characteristics of impaired metabolic health are associated with a high risk of severe COVID-19.
NATURE REVIEWS ENDOCRINOLOGY
(2021)
Review
Endocrinology & Metabolism
Maria Foldi et al.
Summary: This study found that patients with critical condition in COVID-19, including those requiring intensive care and invasive mechanical ventilation, had significantly higher visceral fat area (VFA) values. Therefore, abdominal adiposity appears to be a risk factor in COVID-19, and patients with central obesity may require special attention.
Article
Biotechnology & Applied Microbiology
Meng Wu et al.
Summary: This study examined the potential infection of ovarian cells by SARS-CoV-2, focusing on the expression of ACE2 and TMPRSS2 receptors. The analysis showed that these receptors were mainly expressed in oocytes, with no significant differences between age groups or ovarian reserves. However, pathways related to viral infection were more enriched in ACE2-positive ovarian cells, indicating a potential targeting of specific ovarian cells by SARS-CoV-2. Further research is needed to investigate the long-term effects of SARS-CoV-2 infection on ovarian function.
Article
Multidisciplinary Sciences
Yuanyuan Qiao et al.
Summary: Research has shown that androgens regulate the expression of ACE2, TMPRSS2, and AR in lung epithelial cells, affecting the risk of COVID-19 infection in males over 70 years old. The use of AR or BET antagonists can inhibit SARS-CoV-2 infection, providing support for further investigation into transcriptional inhibition for the treatment or prevention of COVID-19.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Microbiology
Zhiqi Song et al.
Summary: The study found that Syrian hamsters are highly susceptible to SARS-CoV-2, showing pulmonary and extrapulmonary organ damage 3-7 days post infection. Through qRT-PCR, in situ hybridization, and immunohistochemistry, abundant viral RNA and antigen expression were detected in organs such as the spleen, lymph nodes, different segments of the alimentary tract, kidney, adrenal gland, ovary, vesicular gland, and prostate.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Endocrinology & Metabolism
Yanfei Mao et al.
Summary: This study suggests that COVID-19 may lead to relative adrenal insufficiency in critically ill patients by attacking the adrenal cortex, possibly related to the abnormal expression of ACE2 and TMPRSS2. It is recommended to measure plasma cortisol levels for guiding hormonal therapy based on the findings in this study.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Anuradhaa Subramanian et al.
Summary: The study revealed that women with polycystic ovary syndrome (PCOS) are at an increased risk of COVID-19 infection compared to women without PCOS, with the risk remaining elevated even after adjusting for other variables. Therefore, it is crucial for PCOS patients to adhere to infection control measures during the COVID-19 pandemic.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2021)
Review
Emergency Medicine
Johannes Fessler et al.
Summary: The meta-analysis revealed a significant impact of perioperative COVID-19 infections on mortality among hip fracture patients, with the odds ratio for mortality in patients infected with COVID-19 perioperatively being as high as 6.70. The study suggests that perioperative COVID-19 infections lead to a significantly increased risk of mortality in hip fracture patients.
EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY
(2021)
Review
Endocrinology & Metabolism
Seyed Morsal Mosallami Aghili et al.
Summary: Obesity is associated with the severity of COVID-19, affecting respiratory and immune systems through various mechanisms and predisposing patients to other comorbidities. Preventing weight gain in obese COVID-19 patients is crucial during the pandemic.
INTERNATIONAL JOURNAL OF OBESITY
(2021)
Article
Immunology
Ludivine Grzelak et al.
Summary: In a study of 308 healthcare workers with mild COVID-19, it was found that individuals over 50 years old and with a BMI over 25 kg/m(2) had higher levels of anti-S and anti-N antibodies in the first month. Between months 3-6, 99% of individuals had detectable anti-S antibodies, while 59% had anti-N antibodies. Additionally, anti-S and neutralizing antibodies declined faster in men compared to women, regardless of age and BMI.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Endocrinology & Metabolism
N. R. Fuggle et al.
Summary: The effects of COVID-19 have impacted the management of chronic diseases, including osteoporosis, with increases in telemedicine consultations, delays in DXA scanning, interruptions in medication supply, and reductions in parenteral medication delivery observed globally.
OSTEOPOROSIS INTERNATIONAL
(2021)
Letter
Endocrinology & Metabolism
Thomas H. Brix et al.
LANCET DIABETES & ENDOCRINOLOGY
(2021)
Review
Endocrinology & Metabolism
Nafiye Helvaci et al.
Summary: This study analyzed the prevalence of obesity in COVID-19 patients and found an association between obesity and increased risk of hospitalization, ICU admission, and need for invasive mechanical ventilation. The study suggests that obesity may contribute to the progression of COVID-19 and increase the risk of serious illness in infected individuals.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
David Tak Wai Lui et al.
Summary: This study found that the non-thyroidal illness syndrome was not uncommon even in mild-to-moderate COVID-19 patients. NTIS on admission could independently predict clinical deterioration in COVID-19, regardless of SARS-CoV-2 viral load, age, and markers of inflammation and tissue injury.
CLINICAL ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Danielle K. Longmore et al.
Summary: In adults hospitalized with COVID-19, overweight, obesity, and diabetes were associated with increased odds of requiring respiratory support but were not associated with death. In patients with diabetes, the odds of severe COVID-19 were not increased above the BMI-associated risk.
Letter
Endocrinology & Metabolism
Huei-Kai Huang et al.
DIABETES OBESITY & METABOLISM
(2021)
Review
Endocrinology & Metabolism
Sabrina Schlesinger et al.
Summary: This study aimed to identify high-risk phenotypes of diabetes associated with COVID-19 severity and death, showing that individuals with a more severe course of diabetes have a poorer prognosis of COVID-19 compared with individuals with a milder course of disease.
Review
Endocrinology & Metabolism
Pierpaolo Trimboli et al.
Summary: The size and quality of published data regarding SAT in COVID-19 patients are limited, with only a few case reports and case series available. The clinical presentation of SAT in COVID-19 patients seems to be similar to what is generally expected.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Sophie A. Clarke et al.
Summary: The study found that adrenal and thyroid function in COVID-19 survivors remained intact at least 3 months after acute illness, and persistent fatigue symptoms were not attributed to changes in these functions.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Pediatrics
Jose Villar et al.
Summary: This study evaluated the risks associated with COVID-19 in pregnancy on maternal and neonatal outcomes compared with pregnant individuals without COVID-19, finding that pregnant individuals with COVID-19 were at higher risk for various complications such as preeclampsia, severe infections, and preterm birth. The findings emphasize the importance for pregnant individuals and clinicians to strictly implement recommended COVID-19 preventive measures.
Article
Endocrinology & Metabolism
David A. Jolliffe et al.
Summary: Vitamin D supplementation was found to be safe and reduce the risk of acute respiratory infections, especially when administered in daily doses of 400-1000 IU for up to 12 months and to participants aged 1.00-15.99 years. However, the relevance of these findings to COVID-19 is uncertain and further investigation is needed.
LANCET DIABETES & ENDOCRINOLOGY
(2021)
Article
Cell Biology
Danyong Liu et al.
Review
Infectious Diseases
Zelalem G. Dessie et al.
Summary: Chronic comorbidities, complications, and demographic factors such as acute kidney injury, COPD, diabetes, hypertension, CVD, cancer, increased D-dimer, male gender, older age, current smoker, and obesity are identified as clinical risk factors for fatal outcomes related to coronavirus mortality, according to large dataset from 42 studies involving 423,117 patients. The findings provide valuable insights for future research, control, and prevention of the disease.
BMC INFECTIOUS DISEASES
(2021)
Article
Cell Biology
Xiao-Hong Yao et al.
Summary: The study profiles 26 COVID-19 autopsy cases from Wuhan and determines the systemic distribution of SARS-CoV-2 in critically ill patients. It reveals that SARS-CoV-2 may invade multiple organs and utilize physiological barriers as entry ports for systemic dissemination, shedding light on novel COVID-19 treatment development.
Article
Critical Care Medicine
Michaela R. Anderson et al.
Summary: The prevalence of obesity is increasing globally. Studies show that obesity is associated with improved survival in critical illness, but also increased risk of intubation and death in SARS-CoV-2 infection. Respiratory mechanics changes in obese patients can lead to complications such as expiratory flow limitation and hypoxemia.
Review
Endocrinology & Metabolism
Timotius Ivan Hariyanto et al.
Summary: The study suggests that pre-admission use of GLP-1RA may offer beneficial effects on Covid-19 mortality in patients with diabetes mellitus, but more randomized clinical trials are needed to confirm this conclusion.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Immunology
Alexis R. Demonbreun et al.
Summary: In a community cohort without prior COVID-19 infection, women showed a stronger antibody response to COVID-19 mRNA vaccination compared to men, especially after the first dose. After two doses, women continued to have significantly higher antibody levels than men, although the virus neutralization rate was similar. Sex-specific antibody responses to mRNA vaccination provide insights into vaccine protection and side effects.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Mari E. K. Niemi et al.
Summary: The genetic make-up of an individual plays a role in susceptibility and response to viral infections. A global network of researchers identified 13 significant genetic loci associated with SARS-CoV-2 infection and severe COVID-19 cases. Mendelian randomization analyses suggest a causal role for smoking and body-mass index in severe COVID-19. Collaboration among human genetics researchers has allowed for the discovery of novel host genetic factors linked to COVID-19.
Article
Obstetrics & Gynecology
Kamila Kolanska et al.
Summary: The study found that a history of mild COVID-19 infection does not appear to affect the ovarian reserve as evaluated by AMH concentrations. While these results are reassuring, further research is needed to assess the actual impact of COVID-19 on pregnancy outcomes in women undergoing ART.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Review
Clinical Neurology
Rafael Martinez-Perez et al.
Summary: This study identified 3 cases of pituitary apoplexy with concomitant COVID-19 infection, with symptoms including headache and vision changes. The patients were successfully treated with surgery and medical management, showing improvement in visual symptoms. The study suggests that COVID-19 infection may be a risk factor for the development of pituitary apoplexy, but further research is needed.
WORLD NEUROSURGERY
(2021)
Letter
Endocrinology & Metabolism
R. A. Misgar et al.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2021)
Review
Public, Environmental & Occupational Health
Barbara Chmielewska et al.
Summary: The COVID-19 pandemic has significantly impacted maternal, fetal, and neonatal outcomes, leading to increased rates of stillbirth, maternal death, surgically managed ectopic pregnancies, and postpartum depression. Disparities exist between high-resource and low-resource settings, emphasizing the urgent need for prioritizing safe, accessible, and equitable maternity care in response to this pandemic and future health crises.
LANCET GLOBAL HEALTH
(2021)
Article
Medicine, General & Internal
Sandeep Dhindsa et al.
Summary: This study found that lower testosterone concentrations in male COVID-19 patients were associated with increased disease severity and inflammation. Estradiol and IGF-1 concentrations were not associated with COVID-19 severity in men. Changes in hormone signaling pathways in monocytes may not correspond to the severity of the disease in COVID-19 patients.
Article
Endocrinology & Metabolism
Junjun Chu et al.
Summary: Cellular lipid synthesis is crucial for SARS-CoV-2 replication. Inhibitors of fatty acid synthase, such as the approved anti-obesity drug orlistat, show potential for preventing and treating COVID-19 by inhibiting viral replication.
Article
Endocrinology & Metabolism
Sofia Battisti et al.
Summary: The prevalence of VFs was similar between COVID-19 and non-COVID-19 patients, but VFs significantly increased short-term mortality risk in those without COVID-19.
Article
Endocrinology & Metabolism
Ilenia Pirola et al.
Summary: Through reviewing the data, we found no increase in the incidence of subacute thyroiditis in the Brescia area in Italy during the COVID-19 pandemic outbreak. Despite one patient being diagnosed with COVID-19 pulmonary infection 7 weeks before being diagnosed with subacute thyroiditis, the remaining patients were not infected with the coronavirus.
Article
Endocrinology & Metabolism
M. Puig-Domingo et al.
Summary: The COVID-19 pandemic has led to significant changes in our daily clinical practice and social relations. The endocrine system plays a crucial role in the disease, with diabetes being a major comorbidity associated with severity and mortality of COVID-19. Obesity, lack of vitamin D, adrenal insufficiency, and other factors also impact the outcome of COVID-19 patients. Adequate management and consideration of endocrine implications in vaccination are essential.
Article
Endocrinology & Metabolism
Wei Ting Gu et al.
Summary: This study revealed a potential impact of SARS-CoV-2 infection on corticotroph cells and adenomas, with low/negative ACE2 expression in PitNET tissues and high AGTR1 expression in normal pituitary and corticotroph adenomas. Serum adrenocorticotropic hormone levels were significantly increased in COVID-19 patients compared to healthy controls, but decreased in critical cases compared to non-critical patients.
Article
Endocrinology & Metabolism
Giulia Carosi et al.
Summary: A retrospective case-control study showed that AI patients who are adequately treated and trained displayed similar incidence of COVID-19 symptoms and disease severity as controls, with no patients requiring hospitalization or experiencing adrenal crisis.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Luigi di Filippo et al.
Summary: This study investigated the prevalence and clinical impact of vertebral fractures (VFs) in COVID-19 patients, finding that patients with VFs were more likely to have comorbidities like hypertension and coronary artery disease, require noninvasive mechanical ventilation, and have a higher mortality rate, especially those with severe VFs. The study suggests that morphometric thoracic vertebral evaluation should be performed in all suspected COVID-19 patients undergoing chest x-rays.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Bernard Khoo et al.
Summary: Most patients with COVID-19 present with euthyroidism. Mild reductions in TSH and FT4 were observed in COVID-19 patients, consistent with a nonthyroidal illness syndrome. In survivors of COVID-19, thyroid function tests at follow-up returned to baseline.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Virology
Fanfan Zeng et al.
JOURNAL OF MEDICAL VIROLOGY
(2020)
Article
Medicine, General & Internal
Sara Y. Tartof et al.
ANNALS OF INTERNAL MEDICINE
(2020)
Letter
Immunology
Aristo Vojdani et al.
CLINICAL IMMUNOLOGY
(2020)
Review
Endocrinology & Metabolism
John P. Bilezikian et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2020)
Article
Endocrinology & Metabolism
Vsevolod A. Zinserling et al.
HORMONE AND METABOLIC RESEARCH
(2020)
Letter
Endocrinology & Metabolism
Tricia Tan et al.
LANCET DIABETES & ENDOCRINOLOGY
(2020)
Letter
Endocrinology & Metabolism
Ilaria Muller et al.
LANCET DIABETES & ENDOCRINOLOGY
(2020)
Article
Critical Care Medicine
Christian Karagiannidis et al.
LANCET RESPIRATORY MEDICINE
(2020)
Article
Endocrinology & Metabolism
Alessandro Brancatella et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2020)
Article
Multidisciplinary Sciences
Elizabeth J. Williamson et al.
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Medicine, General & Internal
Franck Mauvais-Jarvis et al.
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Multidisciplinary Sciences
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Multidisciplinary Sciences
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NATURE COMMUNICATIONS
(2020)
Article
Multidisciplinary Sciences
Hannah Peckham et al.
NATURE COMMUNICATIONS
(2020)
Article
Infectious Diseases
Brian Hanley et al.
Review
Urology & Nephrology
Katrina M. Mirabito Colafella et al.
NATURE REVIEWS NEPHROLOGY
(2018)
Review
Immunology
Sabra L. Klein et al.
NATURE REVIEWS IMMUNOLOGY
(2016)
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Critical Care Medicine
Yasser Sakr et al.
CRITICAL CARE MEDICINE
(2015)
Article
Endocrinology & Metabolism
Eric Fliers et al.
LANCET DIABETES & ENDOCRINOLOGY
(2015)
Review
Endocrinology & Metabolism
Akira Kawashima et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2011)
Review
Critical Care Medicine
Paul E. Marik et al.
CRITICAL CARE MEDICINE
(2008)
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Oncology
YQ Ding et al.
JOURNAL OF PATHOLOGY
(2003)
Article
Cardiac & Cardiovascular Systems
L Gruberg et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2002)