4.6 Article

LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Genetics & Heredity

Irisin improves insulin resistance by inhibiting autophagy through the PI3K/Akt pathway in H9c2 cells

Rongjing Song et al.

Summary: Irisin, a recently discovered myokine, has shown potential in increasing the insulin sensitivity of cardiomyocytes by activating the PI3K/Akt pathway and inhibiting autophagy.
Review Cardiac & Cardiovascular Systems

NRF2 in Cardiovascular Diseases: a Ray of Hope!

Ruju Vashi et al.

Summary: Heart failure is a global pandemic affecting millions worldwide. Imbalanced redox homeostasis in cardiac cells leads to various cardiovascular diseases, with NRF2 potentially serving as a target for treatment. NRF2 activators may attenuate hemodynamic stress and have therapeutic effects in cardiovascular diseases.

JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH (2021)

Review Cardiac & Cardiovascular Systems

MicroRNAs and long non-coding RNAs in the pathophysiological processes of diabetic cardiomyopathy: emerging biomarkers and potential therapeutics

Daniel Jakubik et al.

Summary: Research suggests that miRNAs and lncRNAs play a crucial role in the development of diabetic cardiomyopathy, serving as potential biomarkers for diagnosis, prognosis, and therapeutic strategies.

CARDIOVASCULAR DIABETOLOGY (2021)

Article Cell Biology

Sufentanil Protects the Liver from Ischemia/Reperfusion-Induced Inflammation and Apoptosis by Inhibiting ATF4-Induced TP53BP2 Expression

Ling Zhou et al.

Summary: The study demonstrated that sufentanil exerts a significant protective effect against liver I/R injury by inhibiting inflammatory factors and reducing hepatocyte apoptosis. TP53BP2 is a key target for sufentanil in protecting the liver, with ATF4 potentially influencing sufentanil's protective effects by regulating TP53BP2 expression.

INFLAMMATION (2021)

Article Oncology

lncRNA-MALAT1 promotes high glucose-induced H9C2 cardiomyocyte pyroptosis by downregulating miR-141-3p expression

Aishan Wu et al.

Summary: This study demonstrated that lncRNA-MALAT1 targeted miR-141-3p to promote HG-induced pyroptosis in H9C2 cardiomyocytes.

MOLECULAR MEDICINE REPORTS (2021)

Review Cell Biology

Role of PI3K/Akt signaling pathway in cardiac fibrosis

Wuming Qin et al.

Summary: Cardiac fibrosis is a common pathological change in heart failure and other cardiovascular diseases, with the PI3K/Akt signaling pathway playing a crucial role in regulating its occurrence, progression, and pathological formation.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2021)

Article Biochemistry & Molecular Biology

LncRNA MALAT1 regulates diabetic cardiac fibroblasts through the Hippo-YAP signaling pathway

Jiangwen Liu et al.

BIOCHEMISTRY AND CELL BIOLOGY (2020)

Review Cell Biology

Mechanisms, regulation and functions of the unfolded protein response

Claudio Hetz et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)

Article Environmental Sciences

Luteolin-mediated PI3K/AKT/Nrf2 signaling pathway ameliorates inorganic mercury-induced cardiac injury

Ruiqi Baiyun et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2018)

Article Medicine, General & Internal

Anti-apoptotic effect of Suxiao Jiuxin Pills against hypoxia-induced injury through PI3K/Akt/GSK3β pathway in HL-1 cardiomyocytes

Yiping Li et al.

JOURNAL OF THE CHINESE MEDICAL ASSOCIATION (2018)

Review Biochemistry & Molecular Biology

The Unfolded Protein Response and Cell Fate Control

Claudio Hetz et al.

MOLECULAR CELL (2018)

Review Cardiac & Cardiovascular Systems

Current status and strategies of long noncoding RNA research for diabetic cardiomyopathy

Tarun Pant et al.

BMC CARDIOVASCULAR DISORDERS (2018)

Review Biochemistry & Molecular Biology

PI3Kinases in Diabetes Mellitus and Its Related Complications

Angelo Maffei et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Biochemistry & Molecular Biology

Endoplasmic Reticulum (ER) Stress and Endocrine Disorders

Daisuke Ariyasu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Biochemistry & Molecular Biology

CRISPR/Cas-based screening of long non-coding RNAs (lncRNAs) in macrophages with an NF-κB reporter

Sergio Covarrubias et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2017)

Review Medicine, Research & Experimental

Role of microRNAs in the pathogenesis of diabetic cardiomyopathy

Xinyu Liu et al.

BIOMEDICAL REPORTS (2017)

Article Biochemistry & Molecular Biology

Endoplasmic reticulum stress and Nrf2 signaling in cardiovascular diseases

Luciano Cominacini et al.

FREE RADICAL BIOLOGY AND MEDICINE (2015)

Article Biochemistry & Molecular Biology

Novel Long Noncoding RNAs (lncRNAs) in Myogenesis: a miR-31 Overlapping lncRNA Transcript Controls Myoblast Differentiation

Monica Ballarino et al.

MOLECULAR AND CELLULAR BIOLOGY (2015)

Review Oncology

Targeting PI3K/Akt/mTOR signaling in cancer

Camillo Porta et al.

FRONTIERS IN ONCOLOGY (2014)

Article Cardiac & Cardiovascular Systems

Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes

Elisa Ramirez et al.

CARDIOVASCULAR DIABETOLOGY (2013)

Review Neurosciences

Mitochondria-associated ER membranes in Alzheimer disease

Eric A. Schon et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

Autophagosomes form at ER-mitochondria contact sites

Maho Hamasaki et al.

NATURE (2013)

Review Biochemistry & Molecular Biology

Recent advances in understanding the biochemical and molecular mechanism of diabetic cardiomyopathy

Jiang-Wen Liu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)

Article Medicine, Research & Experimental

ER stress in the brain subfornical organ mediates angiotensin-dependent hypertension

Colin N. Young et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Review Biochemistry & Molecular Biology

ER stress-induced inflammation: does it aid or impede disease progression?

Abhishek D. Garg et al.

TRENDS IN MOLECULAR MEDICINE (2012)

Article Endocrinology & Metabolism

SIRT1, a Calorie Restriction Mimetic, in a New Therapeutic Approach for Type 2 Diabetes Mellitus and Diabetic Vascular Complications

Shinji Kume et al.

Endocrine Metabolic & Immune Disorders-Drug Targets (2012)

Review Immunology

Obesity and endoplasmic reticulum (ER) stresses

Yamini B. Tripathi et al.

FRONTIERS IN IMMUNOLOGY (2012)

Article Physiology

UPR induces transient burst of apoptosis in islets of early lactating rats through reduced AKT phosphorylation via ATF4/CHOP stimulation of TRB3 expression

Carla R. Bromati et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2011)

Article Endocrinology & Metabolism

Diabetic cardiomyopathy, causes and effects

Sihem Boudina et al.

REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2010)

Article Endocrinology & Metabolism

Cardioprotective effect of vitamin E: rescues of diabetes-induced cardiac malfunction, oxidative stress, and apoptosis in rat

Alireza Shirpoor et al.

JOURNAL OF DIABETES AND ITS COMPLICATIONS (2009)

Article Cardiac & Cardiovascular Systems

Myocardial Fas ligand expression increases susceptibility to AZT-induced cardiomyopathy

Enkhsaikhan Purevjav et al.

CARDIOVASCULAR TOXICOLOGY (2007)

Review Endocrinology & Metabolism

Diabetic cardiomyopathy: Evidence, mechanisms, and therapeutic implications

ZY Fang et al.

ENDOCRINE REVIEWS (2004)

Article Medicine, General & Internal

CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma.

B Coiffier et al.

NEW ENGLAND JOURNAL OF MEDICINE (2002)