Amino Acid Surfactant-Induced Superfast Gelation of Silk Fibroin for Treating Noncompressible Hemorrhage

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Review Engineering, Biomedical

A review of treatments for non-compressible torso hemorrhage (NCTH) and internal bleeding

Celestine Hong et al.

Summary: Non-compressible torso hemorrhage (NCTH) is a life-threatening condition that requires immediate treatment. Current management strategies involve fluid resuscitation, vessel occlusion, and fibrin sealants. Researchers have proposed alternative treatments and evaluated their efficacy through various injury models. This review provides an overview of the current treatment options and research available in the field, aiming to facilitate the development of safer and more effective therapies for NCTH.

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Effect of pH on the Conformational Transition of Silk Fibroin in Aqueous Solution Monitored by Thioflavin-T Fluorescence

Ben Jia et al.

Summary: This study explored the potential application of Thioflavin-T as a tool for monitoring the pH-induced structural transitions of silk fibroin in low solution concentrations. The results showed a significant increase in ThT emission intensities as pH decreased, indicating conformational transitions in SF. The information obtained can be used for developing noninvasive monitoring methods for SF assembly behavior and in vitro fluorescence imaging.

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Amino Acid Surfactant-Induced Superfast Gelation of Silk Fibroin for Treating Noncompressible Hemorrhage

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