4.7 Article

A small molecule inhibitor of NFκB blocks ER stress and the NLRP3 inflammasome and prevents progression of pancreatitis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ

Karen Heyninck et al.

BIOCHEMICAL PHARMACOLOGY (2014)

Article Biochemistry & Molecular Biology

Endoplasmic Reticulum Stress Is Chronically Activated in Chronic Pancreatitis

Raghuwansh P. Sah et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Review Gastroenterology & Hepatology

New insights into the pathogenesis of pancreatitis

Raghuwansh P. Sah et al.

CURRENT OPINION IN GASTROENTEROLOGY (2013)

Article Gastroenterology & Hepatology

Deletion of IκBα Activates RelA to Reduce Acute Pancreatitis in Mice Through Up-regulation of Spi2A

Patrick Neuhoefer et al.

GASTROENTEROLOGY (2013)

Editorial Material Gastroenterology & Hepatology

Nuclear Factor-kappa B in Pancreatitis: Jack-of-All-Trades, But Which One Is More Important?

Ilya Gukovsky et al.

GASTROENTEROLOGY (2013)

Article Gastroenterology & Hepatology

Activation of Nuclear Factor-kappa B in Acinar Cells Increases the Severity of Pancreatitis in Mice

Haojie Huang et al.

GASTROENTEROLOGY (2013)

Article Gastroenterology & Hepatology

Cerulein-Induced Chronic Pancreatitis Does Not Require Intra-Acinar Activation of Trypsinogen in Mice

Raghuwansh P. Sah et al.

GASTROENTEROLOGY (2013)

Review Gastroenterology & Hepatology

Genetic Risk Factors for Pancreatic Disorders

David C. Whitcomb

GASTROENTEROLOGY (2013)

Review Gastroenterology & Hepatology

Models of Acute and Chronic Pancreatitis

Markus M. Lerch et al.

GASTROENTEROLOGY (2013)

Review Biochemistry & Molecular Biology

The complexity of NF-κB signaling in inflammation and cancer

Bastian Hoesel et al.

MOLECULAR CANCER (2013)

Review Immunology

Activation and regulation of the inflammasomes

Eicke Latz et al.

NATURE REVIEWS IMMUNOLOGY (2013)

Review Pharmacology & Pharmacy

Molecular insight in the multifunctional activities of Withaferin A

Wim Vanden Berghe et al.

BIOCHEMICAL PHARMACOLOGY (2012)

Article Gastroenterology & Hepatology

Involvement of Nuclear Factor Kappa B in High-Fat Diet-Related Pancreatic Fibrosis in Rats

Ming-Xian Yan et al.

GUT AND LIVER (2012)

Article Surgery

Total Pancreatectomy and Islet Autotransplantation for Chronic Pancreatitis

David E. R. Sutherland et al.

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS (2012)

Article Gastroenterology & Hepatology

TLR9 and the NLRP3 Inflammasome Link Acinar Cell Death With Inflammation in Acute Pancreatitis

Rafaz Hoque et al.

GASTROENTEROLOGY (2011)

Review Multidisciplinary Sciences

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

Peter Walter et al.

SCIENCE (2011)

Review Biochemistry & Molecular Biology

The Inflammasomes

Kate Schroder et al.

Article Biochemistry & Molecular Biology

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

Sudan He et al.

Review Biotechnology & Applied Microbiology

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

Inki Kim et al.

NATURE REVIEWS DRUG DISCOVERY (2008)

Review Cell Biology

Signal integration in the endoplasmic reticulum unfolded protein response

David Ron et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)

Article Medicine, Research & Experimental

Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo

Bernd Baumann et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Biochemistry & Molecular Biology

Withaferin A strongly elicits IκB kinase β hyperphosphorylation concomitant with potent inhibition of its kinase activity

Mary Kaileh et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Gastroenterology & Hepatology

Acute pancreatitis: Bench to the bedside

Stephen J. Pandol et al.

GASTROENTEROLOGY (2007)

Review Microbiology

How do neutrophils and pathogens interact?

A Mayer-Scholl et al.

CURRENT OPINION IN MICROBIOLOGY (2004)

Article Medicine, Research & Experimental

Attenuated cerulein-induced pancreatitis in nuclear factor-κB-deficient mice

D Altavilla et al.

LABORATORY INVESTIGATION (2003)

Article Gastroenterology & Hepatology

Risk of pancreatic adenocarcinoma in chronic pancreatitis

D Malka et al.

Article Gastroenterology & Hepatology

NF-κB activation in pancreas induces pancreatic and systemic inflammatory response

XQ Chen et al.

GASTROENTEROLOGY (2002)

Article Gastroenterology & Hepatology

Repetitive self-limited acute pancreatitis induces pancreatic fibrogenesis in the mouse

BA Neuschwander-Tetri et al.

DIGESTIVE DISEASES AND SCIENCES (2000)