期刊
CASE REPORTS IN GASTROINTESTINAL MEDICINE
卷 2022, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2022/3443141
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In this case, a young female presented with severe abdominal pain and was diagnosed with lupus enteritis, nephritis, and pancytopenia. Treatment with plasmapheresis and low-dose intravenous rituximab resulted in significant improvement, and the patient remained in remission one year later.
Background. Although lupus enteritis is a rare manifestation of systemic lupus erythematosus yet results in significant distress. This disorder contributes to diagnostic and therapeutic dilemma leading to enhanced mortality. Case Description. We report a case history of a 29-year-old female who presented with severe abdominal pain, watery stools, and vomiting, and later on, she developed pancytopenia and renal impairment. On intensive workup, diagnosis of lupus-associated enteritis, nephritis, and pancytopenia was discovered. She improved drastically on initiation of plasmapheresis followed by low-dose intravenous rituximab. One year posttreatment, she remained in complete remission. Conclusion. From this case, it can be suggested that in a young female with intractable abdominal pain, the remote possibility of lupus enteritis must be kept in mind. Besides this, plasmapheresis can have a potential role in refractory lupus enteritis. Furthermore, low-dose intravenous rituximab can be a safe and cost-effective treatment option in achieving sustained remission of clinical and laboratory parameters in lupus enteritis.
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