期刊
MATERIALS TODAY BIO
卷 16, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.mtbio.2022.100394
关键词
Microspheres; Drug release; Micro fluidics; Polysaccharide; Protein; Tissue engineering
资金
- Scientific research start-up fund for high- level talents of Yulin Normal University [G2022ZK02]
This paper provides a systematic review of the application of sustained-release drug microspheres in tissue engineering, including the introduction of drug delivery systems, types and characteristics of microspheres, preparation methods and materials, applications, and future prospects.
Sustained-release drug-loaded microspheres provide a long-acting sustained release, with targeted and other ef-fects. There are many types of sustained-release drug microspheres and various preparation methods, and they are easy to operate. For these reasons, they have attracted widespread interest and are widely used in tissue engi-neering and other fields. In this paper, we provide a systematic review of the application of sustained-release drug microspheres in tissue engineering. First, we introduce this new type of drug delivery system (sustained-release drug carriers), describe the types of sustained-release drug microspheres, and summarize the characteristics of different microspheres. Second, we summarize the preparation methods of sustained-release drug microspheres and summarize the materials required for preparing microspheres. Third, various applications of sustained-release drug microspheres in tissue engineering are summarized. Finally, we summarize the shortcomings and discuss future prospects in the development of sustained-release drug microspheres. The purpose of this paper was to provide a further systematic understanding of the application of sustained-release drug microspheres in tissue engineering for the personnel engaged in related fields and to provide inspiration and new ideas for studies in related fields.
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