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Paola Rusmini et al.
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Parisa Lotfi et al.
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Julie A. Morgan et al.
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Anthea Di Rita et al.
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Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways
Lisa A. Lesniewski et al.
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The mammalian ULK1 complex and autophagy initiation
Maria Zachari et al.
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Aaron M. Gusdon et al.
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Yujiao Lu et al.
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Xianjuan Kou et al.
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Li Luo et al.
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Xiaojuan Han et al.
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Graeme Hewitt et al.
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Daniel J. Klionsky et al.
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
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Taichi Hara et al.
NATURE (2006)
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