Applications of Smartphone-Based Aptasensor for Diverse Targets Detection

Aptamers are a particular class of functional recognition ligands with high specificity and affinity to their targets. As the candidate recognition layer of biosensors, aptamers can be used to sense biomolecules. Aptasensors, aptamer-based biosensors, have been demonstrated to be specific, sensitive, and cost-effective. Furthermore, smartphone-based devices have shown their advantages in binding to aptasensors for point-of-care testing (POCT), which offers an immediate or spontaneous responding time for biological testing. This review describes smartphone-based aptasensors to detect various targets such as metal ions, nucleic acids, proteins, and cells. Additionally, the focus is also on aptasensors-related technologies and configurations.

Automated summary

Aptamers are functional recognition ligands with high specificity and affinity, which can be utilized in biosensors for sensing biomolecules. Aptasensors, based on aptamers, are specific, sensitive, and cost-effective, and have shown advantages when combined with smartphone devices for point-of-care testing.