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Scientific Evidence about the Risks of Micro and Nanoplastics (MNPLs) to Human Health and Their Exposure Routes through the Environment

期刊

TOXICS
卷 10, 期 6, 页码 -

出版社

MDPI
DOI: 10.3390/toxics10060308

关键词

microplastics; ecosystem; human health; toxicity

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  1. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior-Brasil (CAPES) [001]

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Plastic is widely produced and consumed by humans, leading to the presence of microplastics and nanoplastics in various ecosystems. These particles can be found in soil, water, and air, and exposure to them mainly occurs through ingestion and inhalation. Studies have shown that exposure to these particles can cause respiratory tract damage and other health issues. However, there is limited data available on the toxicity and exposure levels of microplastics and nanoplastics.
Nowadays, a large amount and variety of plastic is being produced and consumed by human beings on an enormous scale. Microplastics and nanoplastics (MNPLs) have become ubiquitous since they can be found in many ecosystem components. Plastic particles can be found in soil, water, and air. The routes of human exposure are numerous, mainly involving ingestion and inhalation. Once ingested, these particles interact with the gastrointestinal tract and digestive fluids. They can adsorb substances such as additives, heavy metals, proteins, or even microorganisms on their surface, which can cause toxicity. During inhalation, they can be inhaled according to their respective sizes. Studies have reported that exposure to MNPLs can cause damage to the respiratory tract, creating problems such as bronchitis, asthma, fibrosis, and pneumothorax. The reports of boards and committees indicate that there is little data published and available on the toxicity of MNPLs as well as the exposure levels in humans. Despite the well-established concept of MNPLs, their characteristics, and presence in the environment, little is known about their real effects on human health and the environment.

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