4.7 Article

Effect of Pravastatin and Simvastatin on the Reduction of Cytochrome C

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biophysics

Characterization of oxidation of glutathione by cytochrome c

K. B. Csomo et al.

Summary: The study found that pH, Ca2+, Mg2+, and anionic phospholipids can influence the reduction of cytochrome c by glutathione, and mitochondrial oxygen consumption is also affected. Glutathione can increase mitochondrial oxygen consumption under specific conditions, and decreased levels of glutathione are associated with apoptosis.

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2022)

Article Gastroenterology & Hepatology

A Meta-Analysis of Statin Use and Risk of Hepatocellular Carcinoma

Yikai Wang et al.

Summary: This meta-analysis study found that the use of statins is closely associated with a lower risk of liver cancer. Statin users, both in Asian and Western populations, have a reduced risk of developing hepatocellular carcinoma. Statins also have protective effects after hepatitis B and hepatitis C virus infections. In addition, statins are beneficial for individuals with chronic liver disease and the general population. Lipophilic statins have a significant preventive effect on hepatocellular carcinoma, while hydrophilic statins do not show a clear effect.

CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2022)

Article Toxicology

Atorvastatin and pravastatin stimulate nitric oxide and reactive oxygen species generation, affect mitochondrial network architecture and elevate nicotinamide N-methyltransferase level in endothelial cells

Dorota Dymkowska et al.

Summary: Statins have various effects on endothelial cells, including activation of proinflammatory response, modulation of oxidative stress, regulation of antioxidative response, and alteration of mitochondrial function. These effects may be related to changes in AMP-activated protein kinase, Sirt1, and nicotinamide N-methyltransferase protein levels.

JOURNAL OF APPLIED TOXICOLOGY (2021)

Review Biochemistry & Molecular Biology

A comprehensive review on the lipid and pleiotropic effects of pitavastatin

Amirhossein Sahebkar et al.

Summary: Pitavastatin is a unique lipophilic statin with pleiotropic effects, including reducing inflammation and oxidative stress. It appears to be the safest statin based on available studies, with multiple therapeutic effects that make it an interesting option for the treatment of various human diseases.

PROGRESS IN LIPID RESEARCH (2021)

Article Oncology

Potentiating the Cytotoxic Activity of a Novel Simvastatin-Loaded Cubosome against Breast Cancer Cells: Insights on Dual Cell Death via Ferroptosis and Apoptosis

Yara E. Elakkad et al.

Summary: SIM-CB is a promising carrier to enhance the therapeutic potential of simvastatin against breast cancer cells, potentiating both apoptosis and ferroptosis.

BREAST CANCER-TARGETS AND THERAPY (2021)

Review Chemistry, Multidisciplinary

Structure and Mechanism of Respiratory III-IV Supercomplexes in Bioenergetic Membranes

Peter Brzezinski et al.

Summary: In aerobic organisms, the free energy from electron transfer in the respiratory chain is converted into a proton electrochemical gradient across the membrane for energy storage. Cytochrome c oxidase and cytochrome bc1 combine to form supercomplexes in many organisms, facilitating energy conversion through complex mechanisms and structures.

CHEMICAL REVIEWS (2021)

Review Cell Biology

Wheel and Deal in the Mitochondrial Inner Membranes: The Tale of Cytochrome c and Cardiolipin

Antonio Diaz-Quintana et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)

Article Obstetrics & Gynecology

Pravastatin induces NO synthesis by enhancing microsomal arginine uptake in healthy and preeclamptic placentas

Zita Panczel et al.

BMC PREGNANCY AND CHILDBIRTH (2019)

Review Pharmacology & Pharmacy

Statins and their increased risk of inducing diabetes

Aris P. Agouridis et al.

EXPERT OPINION ON DRUG SAFETY (2015)

Article Medicine, General & Internal

Statins and gastrointestinal cancers

Sagi Veronika et al.

ORVOSI HETILAP (2014)

Review Cardiac & Cardiovascular Systems

Effect of HMG-CoA reductase inhibitors on vascular cell apoptosis: Beneficial or detrimental?

Niki Katsiki et al.

ATHEROSCLEROSIS (2010)

Article Chemistry, Multidisciplinary

Heterolytic Reduction of Fatty Acid Hydroperoxides by Cytochrome c/Cardiolipin Complexes: Antioxidant Function in Mitochondria

Natalia A. Belikova et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Article Biochemistry & Molecular Biology

Toxicity of statins on rat skeletal muscle mitochondria

P. Kaufmann et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2006)

Article Biochemistry & Molecular Biology

Does the redox status of cytochrome C act as a fail-safe mechanism in the regulation of programmed cell death?

JT Hancock et al.

FREE RADICAL BIOLOGY AND MEDICINE (2001)