4.6 Article

Chitosan Is Necessary for the Structure of the Cell Wall, and Full Virulence of Ustilago maydis

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Summary: The basidiomycete Ustilago maydis, a biotrophic fungus, possesses a family of chitin deacetylases (CDAs) with seven genes that play discrete and redundant roles in virulence and cell wall integrity. The study shows that different CDAs have specific functions in evading plant immune recognition and modifying chitin to chitosan. Surprisingly, the simultaneous inactivation of all seven genes is not tolerated, indicating the essential role of chitosan for the fungus's viability.
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