4.6 Editorial Material

Ammonia to chiral α-amino acid

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Enantioselective synthesis of amino acids from ammonia

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Summary: This study introduces a strategy for directly preparing chiral alpha-amino acids from ammonia. The cooperative action of copper complexes and chiral hydrogen-bond donors enables enantioselective construction of C-N bonds, achieving high yield and enantioselectivity. The method allows for the production of natural and non-natural chiral alpha-amino acids with various applications.

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