Ammonia to chiral α-amino acid

The direct use of ammonia for asymmetric synthesis is highly sought after. Now, an efficient enantioselective carbene insertion into the N-H bond of ammonia has been developed, producing diverse valuable chiral alpha-amino acids.

Automated summary

An efficient method for enantioselective carbene insertion into ammonia has been discovered, resulting in the production of diverse valuable chiral alpha-amino acids.