☆ 4.6 Editorial Material

Editorial: Capturing Biological Complexity and Heterogeneity Using Multidimensional MRI

FRONTIERS IN PHYSICS (2022)

Computing and visualising intra-voxel orientation-specific relaxation-diffusion features in the human brain

Joao P. de Almeida Martins et al.

Summary: Diffusion MRI techniques are widely used to study the human brain connectome, and a new 5D relaxation-diffusion correlation framework has been introduced to address challenges in resolving white matter fibers. This framework allows for the derivation of fiber-specific metrics and a deeper understanding of microstructural properties in the brain.

HUMAN BRAIN MAPPING (2021)

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Article Clinical Neurology

Diffuse axonal injury has a characteristic multidimensional MRI signature in the human brain

Dan Benjamini et al.

Summary: The study focused on investigating the changes in different MRI parameters related to DAI in traumatic brain injury, using a combination of MRI and histopathology. The results suggest that multidimensional MRI can effectively differentiate the severity of axonal injury and may serve as non-invasive biomarkers for DAI detection.

BRAIN (2021)

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Review Radiology, Nuclear Medicine & Medical Imaging

Combined diffusion-relaxometry microstructure imaging: Current status and future prospects

Paddy J. Slator et al.

Summary: This article discusses an emerging paradigm in microstructure imaging that combines diffusion-relaxometry imaging to provide a more detailed assessment of tissue microstructure. By varying multiple MR contrast encodings in a multidimensional acquisition space, correlations and coupling between multiple MR parameters can be quantified, enabling the disentangling of multiple tissue compartments within voxels. This allows for the creation of new generation microstructural maps with improved biological sensitivity and specificity.

MAGNETIC RESONANCE IN MEDICINE (2021)

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Article Neurosciences

Direct and specific assessment of axonal injury and spinal cord microenvironments using diffusion correlation imaging

Dan Benjamini et al.

NEUROIMAGE (2020)

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Article Radiology, Nuclear Medicine & Medical Imaging

Combined diffusion-relaxometry MRI to identify dysfunction in the human placenta

Paddy J. Slator et al.

MAGNETIC RESONANCE IN MEDICINE (2019)

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Article Radiology, Nuclear Medicine & Medical Imaging

Compartmental study of T1 and T2 in rat brain and trigeminal nerve in vivo

MD Does et al.

MAGNETIC RESONANCE IN MEDICINE (2002)

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Editorial: Capturing Biological Complexity and Heterogeneity Using Multidimensional MRI

相关参考文献

Computing and visualising intra-voxel orientation-specific relaxation-diffusion features in the human brain

Diffuse axonal injury has a characteristic multidimensional MRI signature in the human brain

Combined diffusion-relaxometry microstructure imaging: Current status and future prospects

Direct and specific assessment of axonal injury and spinal cord microenvironments using diffusion correlation imaging

Combined diffusion-relaxometry MRI to identify dysfunction in the human placenta

Compartmental study of T1 and T2 in rat brain and trigeminal nerve in vivo

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