4.6 Article

Metabolomics and Data-Driven Bioinformatics Revealed Key Maternal Metabolites Related to Fetal Lethality via Di(2-ethylhexyl)phthalate Exposure in Pregnant Mice

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Summary: DEHP, considered an endocrine disruptor chemical (EDC), is widely used in the plastic industry and can have negative effects on placental development and function, potentially impacting fetal growth. Research indicates that DEHP and MEHP can impair key processes in placental development and affect various placental functions. Clinical evidence also supports the connection between DEHP exposure and adverse pregnancy outcomes and pathologies.

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