Expression and Functional Analyses of the WIP Gene Family in Arabidopsis

The WIP family of transcription factors comprises the A1d subgroup of C2H2 zinc finger proteins. This family has six members in Arabidopsis thaliana and most of the known functions have been described by analyzing single knockout mutants. However, it has been shown that WIP2 and its closest paralogs WIP4 and WIP5 have a redundant and essential function in root meristems. It is likely that these and other WIP genes perform more, still unknown, functions. To obtain hints about these other functions, the expression of the six WIP genes was explored. Moreover, phenotypic ana-lyses of overexpressors and wip mutants revealed functions in modulating organ and cell size, stomatal density, and vasculature development.

Automated summary

Some genes in the WIP family play redundant and essential roles in root meristems, while other WIP genes may have additional, unknown functions. Studies have shown that WIP genes are involved in modulating organ and cell size, stomatal density, and vasculature development.