期刊
PATHOGENS
卷 11, 期 8, 页码 -出版社
MDPI
DOI: 10.3390/pathogens11080850
关键词
S. pseudintermedius; transmission; One health; whole genome sequencing; zoonotic; bacterial diversity
类别
This study demonstrates the presence of within-host bacterial diversity in S. pseudintermedius, highlighting the importance of sequencing multiple isolates from each host to study transmission dynamics.
Staphylococcus pseudintermedius can be transmitted between dogs and their owners and can cause opportunistic infections in humans. Whole genome sequencing was applied to identify the relatedness between isolates from human infections and isolates from dogs in the same households. Genome SNP diversity and distribution of plasmids and antimicrobial resistance genes identified related and unrelated isolates in both households. Our study shows that within-host bacterial diversity is present in S. pseudintermedius, demonstrating that multiple isolates from each host should preferably be sequenced to study transmission dynamics.
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