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Cancer Stem Cells and Macrophages: Implications in Tumor Biology and Therapeutic Strategies
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MEDICAL ONCOLOGY (2016)
PI3Kγ is a molecular switch that controls immune suppression
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NATURE (2016)
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WORLD JOURNAL OF GASTROENTEROLOGY (2016)
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Megan M. Kaneda et al.
CANCER DISCOVERY (2016)
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ONCOTARGET (2016)
Epigenetic regulation of cancer biology and anti-tumor immunity by EZH2
Anthos Christofides et al.
ONCOTARGET (2016)
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Hanwen Zhang et al.
ONCOTARGET (2016)
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ONCOTARGET (2016)
Targeting the CCL2-CCR2 signaling axis in cancer metastasis
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ONCOTARGET (2016)
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CELL REPORTS (2016)
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FRONTIERS IN IMMUNOLOGY (2016)
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Hua Wang et al.
ANNALS OF HEMATOLOGY (2015)
The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?
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CELL STEM CELL (2015)
Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms
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CLINICAL CANCER RESEARCH (2015)
Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment
Bruno Sainz et al.
GUT (2015)
Ovarian cancer stem cells induce the M2 polarization of macrophages through the PPARγ and NF-κB pathways
Xinchao Deng et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2015)
Exposure of Tumor-Associated Macrophages to Apoptotic MCF-7 Cells Promotes Breast Cancer Growth and Metastasis
Na Zhou et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma
Oscar W. H. Yeung et al.
JOURNAL OF HEPATOLOGY (2015)
Small Molecule Inhibition of MERTK Is Efficacious in Non-Small Cell Lung Cancer Models Independent of Driver Oncogene Status
Christopher T. Cummings et al.
MOLECULAR CANCER THERAPEUTICS (2015)
Ovarian cancer stem-like cells elicit the polarization of M2 macrophages
Qing Zhang et al.
MOLECULAR MEDICINE REPORTS (2015)
Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth
Wenchao Zhou et al.
NATURE CELL BIOLOGY (2015)
CD14-expressing cancer cells establish the inflammatory and proliferative tumor microenvironment in bladder cancer
Ming T. Cheah et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
Huimin Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis
Xi Feng et al.
ONCOTARGET (2015)
Mer receptor tyrosine kinase is frequently overexpressed in human non-small cell lung cancer, confirming resistance to erlotinib
Shengzhi Xie et al.
ONCOTARGET (2015)
uPAR Induces Expression of Transforming Growth Factor beta and Interleukin-4 in Cancer Cells to Promote Tumor-Permissive Conditioning of Macrophages
Jingjing Hu et al.
AMERICAN JOURNAL OF PATHOLOGY (2014)
Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells
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CANCER CELL (2014)
Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy
Carola H. Ries et al.
CANCER CELL (2014)
Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial-mesenchymal transition in hepatocellular carcinoma
Qing-Min Fan et al.
CANCER LETTERS (2014)
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Tsunaki Yamashina et al.
CANCER RESEARCH (2014)
CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models
Yu Zhu et al.
CANCER RESEARCH (2014)
Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells
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HEPATOLOGY INTERNATIONAL (2014)
Involvement of CXCL14 in osteolytic bone metastasis from lung cancer
Soichi Takiguchi et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
Cytokines driving breast cancer stemness
Andrew R. Chin et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2014)
A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages
Haihui Lu et al.
NATURE CELL BIOLOGY (2014)
Role of macrophage inflammatory protein (MIP)-1α/CCL3 in leukemogenesis
Tomohisa Baba et al.
MOLECULAR & CELLULAR ONCOLOGY (2014)
C-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment
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BREAST CANCER RESEARCH (2014)
Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-Dependent and -Independent Mechanisms
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CLINICAL CANCER RESEARCH (2013)
Inflammatory Monocyte Mobilization Decreases Patient Survival in Pancreatic Cancer: A Role for Targeting the CCL2/CCR2 Axis
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CLINICAL CANCER RESEARCH (2013)
Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation
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EMBO MOLECULAR MEDICINE (2013)
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Jagdeep K. Singh et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2013)
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Stephanie M. Pyonteck et al.
NATURE MEDICINE (2013)
Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer
R. M. A. Linger et al.
ONCOGENE (2013)
High-Infiltration of Tumor-Associated Macrophages Predicts Unfavorable Clinical Outcome for Node-Negative Breast Cancer
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PLOS ONE (2013)
Tumor-Associated Macrophages Regulate Murine Breast Cancer Stem Cells Through a Novel Paracrine EGFR/Stat3/Sox-2 Signaling Pathway
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CANCER RESEARCH (2012)
Macrophage-tumor crosstalk: role of TAMR tyrosine kinase receptors and of their ligands
Thomas Schmidt et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Topical TLR7 Agonist Imiquimod Can Induce Immune-Mediated Rejection of Skin Metastases in Patients with Breast Cancer
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CLINICAL CANCER RESEARCH (2012)
IL10, IL11, IL18 are differently expressed in CD14+ TAMs and play different role in regulating the invasion of gastric cancer cells under hypoxia
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MOLECULAR MEDICINE (2012)
Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma
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NEW ENGLAND JOURNAL OF MEDICINE (2012)
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Monoclonal Antibodies Against Lgr5 Identify Human Colorectal Cancer Stem Cells
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CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
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NATURE (2011)
Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells
Masahisa Jinushi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Alternative activation of tumor-associated macrophages by IL-4 Priming for protumoral functions
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CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis
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CYTOKINE & GROWTH FACTOR REVIEWS (2010)
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LEUKEMIA (2009)
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CANCER RESEARCH (2007)
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