期刊
APPLIED HEALTH ECONOMICS AND HEALTH POLICY
卷 20, 期 5, 页码 769-779出版社
SPRINGER INT PUBL AG
DOI: 10.1007/s40258-022-00747-8
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This study examines the cost-effectiveness and budget impact of implementing a 'soft opt-out' organ donation system for kidney donation. Results show that a 20% increase in organ donation rates could save 650 million Australian dollars and gain 10,400 QALYs, averting more than 1500 deaths. Understanding aversion to a 'soft opt-out' system in Australia is important for future research.
Introduction There is a severe shortage of donor organs globally. There is growing interest in understanding how a 'soft opt-out' organ donation system could help bridge the supply and demand gap for donor organs. This research aims to estimate the cost-effectiveness and budget impact of implementing a 'soft opt-out' organ donation system for kidney donation. Methods A decision-analytic model was developed to estimate the incremental costs from a health system's perspective, quality-adjusted life-years (QALYs), and death averted of people who have kidney failure, comparing a 'soft opt-out' organ donation system to an 'opt-in' system. This study analysed three scenarios where the 'soft opt-out' system generated a 20%, 30%, and 40% increase in deceased organ donation rates over 20 years. A 5-year time horizon was adopted for the budget impact analysis. Results A 20% increase in organ donation rates could have a cost saving of 650 million Australian dollars (A$) and a 10,400-QALY gain. A 20% increase would avert more than 1500 deaths, while a 40% increase would avert 3200 deaths over a time horizon of 20 years. Over the first 5 years, a 20% increase would have a net saving of A$53 million, increasing to A$106 million if the donation rate increases by 40%. Conclusion A 'soft opt-out' organ donation system would return a cost saving for the healthcare system, a net gain in QALYs, and prevention of a significant number of deaths. Advantageous budgetary impact is important, but understanding the aversion for a 'soft opt-out' system in Australia is also important and remains a priority for further research.
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