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Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis
Tobias Zrzavy et al.
BRAIN (2017)
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease
Hadas Keren-Shaul et al.
CELL (2017)
Regulation of microglial activation in stroke
Shou-cai Zhao et al.
ACTA PHARMACOLOGICA SINICA (2017)
Pinocembrin protects hemorrhagic brain primarily by inhibiting toll-like receptor 4 and reducing M1 phenotype microglia
Xi Lan et al.
BRAIN BEHAVIOR AND IMMUNITY (2017)
An early and late peak in microglial activation in Alzheimer's disease trajectory
Zhen Fan et al.
BRAIN (2017)
Next Generation Transcriptomics and Genomics Elucidate Biological Complexity of Microglia in Health and Disease
Paul D. Wes et al.
GLIA (2016)
Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases
Yu Tang et al.
MOLECULAR NEUROBIOLOGY (2016)
Extrastriatal spreading of microglial activation in Parkinson's disease: a positron emission tomography study
Tatsuhiro Terada et al.
ANNALS OF NUCLEAR MEDICINE (2016)
Microglial response to LPS increases in wild-type mice during aging but diminishes in an Alzheimer's mouse model: Implication of TLR4 signaling in disease progression
Michelle Go et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Early and protective microglial activation in Alzheimer's disease: a prospective study using 18F-DPA-714 PET imaging
Lorraine Hamelin et al.
BRAIN (2016)
Neuronal Soluble Fas Ligand Drives M1-Microglia Polarization after Cerebral Ischemia
Hai-Lan Meng et al.
CNS NEUROSCIENCE & THERAPEUTICS (2016)
Molecular Basis of Familial and Sporadic Alzheimer's Disease
Jolanta Dorszewska et al.
CURRENT ALZHEIMER RESEARCH (2016)
The Big-Bang for Modern Glial Biology: Translation and Comments on Pio del Rio-Hortega 1919 Series of Papers on Microglia
Amanda Sierra et al.
GLIA (2016)
Dark microglia: A new phenotype predominantly associated with pathological states
Kanchan Bisht et al.
GLIA (2016)
LRRK2 modulates microglial activity through regulation of chemokine (C-X3-C) receptor 1-mediated signalling pathways
Bo Ma et al.
HUMAN MOLECULAR GENETICS (2016)
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
Yaming Wang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration
Hongwei Qin et al.
JOURNAL OF NEUROSCIENCE (2016)
The Alarmin HMGB1 Mediates Age-Induced Neuroinflammatory Priming
Laura K. Fonken et al.
JOURNAL OF NEUROSCIENCE (2016)
Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury
Alok Kumar et al.
JOURNAL OF NEUROTRAUMA (2016)
Sall1 is a transcriptional regulator defining microglia identity and function
Anne Buttgereit et al.
NATURE IMMUNOLOGY (2016)
Origin, fate and dynamics of macrophages at central nervous system interfaces
Tobias Goldmann et al.
NATURE IMMUNOLOGY (2016)
Microglial brain region-dependent diversity and selective regional sensitivities to aging
Kathleen Grabert et al.
NATURE NEUROSCIENCE (2016)
TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
Felix L. Yeh et al.
NEURON (2016)
New tools for studying microglia in the mouse and human CNS
Mariko L. Bennett et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Untangling the brain's neuroinflammatory and neurodegenerative transcriptional responses
Karpagam Srinivasan et al.
NATURE COMMUNICATIONS (2016)
Microglia Activation and Polarization After Intracerebral Hemorrhage in Mice: the Role of Protease-Activated Receptor-1
Shu Wan et al.
TRANSLATIONAL STROKE RESEARCH (2016)
Interleukin-4 Ameliorates the Functional Recovery of Intracerebral Hemorrhage Through the Alternative Activation of Microglia/Macrophage
Jianjing Yang et al.
FRONTIERS IN NEUROSCIENCE (2016)
Alpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T Mutant
Claire Hoenen et al.
PLOS ONE (2016)
The association between laminin and microglial morphology in vitro
Wing Yip Tam et al.
SCIENTIFIC REPORTS (2016)
Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo
Marta Bolos et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Toll-like Receptors in the Vascular System: Sensing the Dangers Within
Styliani Goulopoulou et al.
PHARMACOLOGICAL REVIEWS (2016)
Endocannabinoids drive the acquisition of an alternative phenotype in microglia
M. Mecha et al.
BRAIN BEHAVIOR AND IMMUNITY (2015)
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer's Disease Model
Yaming Wang et al.
CELL (2015)
New FDA-Approved Disease-Modifying Therapies for Multiple Sclerosis
Clayton English et al.
CLINICAL THERAPEUTICS (2015)
TGF1 inhibits IFN-mediated microglia activation and protects mDA neurons from IFN-driven neurotoxicity
Xiaolai Zhou et al.
JOURNAL OF NEUROCHEMISTRY (2015)
Scavenger receptor SRA attenuates microglia activation and protects neuroinflammatory injury in intracerebral hemorrhage
Zhao Yang et al.
JOURNAL OF NEUROIMMUNOLOGY (2015)
Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner
Jie Pan et al.
JOURNAL OF NEUROINFLAMMATION (2015)
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Deficiency Attenuates Phagocytic Activities of Microglia and Exacerbates Ischemic Damage in Experimental Stroke
Masahito Kawabori et al.
JOURNAL OF NEUROSCIENCE (2015)
The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment
Valeriy G. Ostapchenko et al.
JOURNAL OF NEUROSCIENCE (2015)
Neuronal Interleukin-4 as a Modulator of Microglial Pathways and Ischemic Brain Damage
Xiurong Zhao et al.
JOURNAL OF NEUROSCIENCE (2015)
Microbe- and danger-induced inflammation
Achille Broggi et al.
MOLECULAR IMMUNOLOGY (2015)
Fractalkine Over Expression Suppresses alpha-Synuclein-mediated Neurodegeneration
Kevin R. Nash et al.
MOLECULAR THERAPY (2015)
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
Hirohide Asai et al.
NATURE NEUROSCIENCE (2015)
Toll-like Receptor 4 (TLR4) is Associated with Cerebral Vasospasm and Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage
Chunxiao Ma et al.
NEUROLOGIA MEDICO-CHIRURGICA (2015)
Parkinson disease and incidental Lewy body disease Just a question of time?
Diego Iacono et al.
NEUROLOGY (2015)
Toll-like receptor-4-mediated autophagy contributes to microglial activation and inflammatory injury in mouse models of intracerebral haemorrhage
Z. Yang et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2015)
Diversity and plasticity of microglial cells in psychiatric and neurological disorders
Yutaka Nakagawa et al.
PHARMACOLOGY & THERAPEUTICS (2015)
Alternatively activated microglia and macrophages in the central nervous system
Rafael Franco et al.
PROGRESS IN NEUROBIOLOGY (2015)
Astrocyte Overexpression of Heme Oxygenase-1 Improves Outcome After Intracerebral Hemorrhage
Jing Chen-Roetling et al.
STROKE (2015)
Guidelines for the Management of Spontaneous Intracerebral Hemorrhage A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association
J. Claude Hemphill et al.
STROKE (2015)
Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques
Carlo Condello et al.
NATURE COMMUNICATIONS (2015)
Role of Different Alpha-Synuclein Strains in Synucleinopathies, Similarities with other Neurodegenerative Diseases
Ronald Melki
JOURNAL OF PARKINSONS DISEASE (2015)
Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse
Amir Pozner et al.
Frontiers in Molecular Neuroscience (2015)
Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging
Adam D. Bachstetter et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
Inge R. Holtman et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Microglial A beta Receptors in Alzheimer's Disease
Yang Yu et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2015)
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
Elisa Gomez Perdiguero et al.
NATURE (2015)
Impairment of in vivo calcium signaling in amyloid plaque-associated microglia
Bianca Brawek et al.
ACTA NEUROPATHOLOGICA (2014)
Toll-like receptor 2-mediated alternative activation of microglia is protective after spinal cord injury
David P. Stirling et al.
BRAIN (2014)
Age-dependent changes on TGFβ1 Smad3 pathway modify the pattern of microglial cell activation
Juan E. Tichauer et al.
BRAIN BEHAVIOR AND IMMUNITY (2014)
Neuroprotective effects of argatroban and C5a receptor antagonist (PMX53) following intracerebral haemorrhage
G. Li et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2014)
Characterization of Intermediate Steps in Amyloid Beta (Aβ) Production under Near-native Conditions
Fredrik Olsson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
CD36-Mediated Hematoma Absorption following Intracerebral Hemorrhage: Negative Regulation by TLR4 Signaling
Huang Fang et al.
JOURNAL OF IMMUNOLOGY (2014)
Microglia receptors and their implications in the response to amyloid β for Alzheimer's disease pathogenesis
Deborah Doens et al.
JOURNAL OF NEUROINFLAMMATION (2014)
Progressing haemorrhagic stroke: categories, causes, mechanisms and managements
Shiyu Chen et al.
JOURNAL OF NEUROLOGY (2014)
Stage-Dependent Nigral Neuronal Loss in Incidental Lewy Body and Parkinson's Disease
Anke A. Dijkstra et al.
MOVEMENT DISORDERS (2014)
IgG4 can induce an M2-like phenotype in human monocyte-derived macrophages through FcγRI
Jennifer F. A. Swisher et al.
MABS (2014)
Identification of a unique TGF-β dependent molecular and functional signature in microglia
Oleg Butovsky et al.
NATURE NEUROSCIENCE (2014)
Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice
Marie Orre et al.
NEUROBIOLOGY OF AGING (2014)
Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease
Augusta Pisanu et al.
NEUROBIOLOGY OF DISEASE (2014)
Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
Monica R. P. Elmore et al.
NEURON (2014)
Rod Microglia: A Morphological Definition
Samuel E. Taylor et al.
PLOS ONE (2014)
Synthesis and Propagation of Complement C3 by Microglia/Monocytes in the Aging Retina
Matt Rutar et al.
PLOS ONE (2014)
The influence of AAV2-mediated gene transfer of human IL-10 on neurodegeneration and immune response in a murine model of Parkinson's disease
Ilona Joniec-Maciejak et al.
PHARMACOLOGICAL REPORTS (2014)
Inflammation in intracerebral hemorrhage: From mechanisms to clinical translation
Yu Zhou et al.
PROGRESS IN NEUROBIOLOGY (2014)
Bipolar/rod-shaped microglia are proliferating microglia with distinct M1/M2 phenotypes
Wing Yip Tam et al.
SCIENTIFIC REPORTS (2014)
Thrombin-Induced Cerebral Hemorrhage: Role of Protease-Activated Receptor-1
Yingying Cheng et al.
TRANSLATIONAL STROKE RESEARCH (2014)
Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson's disease patients
Karlijn J. Doorn et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)
Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro
Vibol Chhor et al.
BRAIN BEHAVIOR AND IMMUNITY (2013)
Early morphofunctional plasticity of microglia in response to acute lipopolysaccharide
C. Madore et al.
BRAIN BEHAVIOR AND IMMUNITY (2013)
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
Christopher N. Parkhurst et al.
CELL (2013)
Microglial calcium signaling in the adult, aged and diseased brain
Bianca Brawek et al.
CELL CALCIUM (2013)
Microglial Responses after Ischemic Stroke and Intracerebral Hemorrhage
Roslyn A. Taylor et al.
CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2013)
Commentary: Progressive inflammation as a contributing factor to early development of Parkinson's disease
Suraj Pradhan et al.
EXPERIMENTAL NEUROLOGY (2013)
The Adenosine-Dependent Angiogenic Switch of Macrophages to an M2-Like Phenotype is Independent of Interleukin-4 Receptor Alpha (IL-4Rα) Signaling
Christopher James Ferrante et al.
INFLAMMATION (2013)
A Dramatic Increase of C1q Protein in the CNS during Normal Aging
Alexander H. Stephan et al.
JOURNAL OF NEUROSCIENCE (2013)
How Do Immune Cells Support and Shape the Brain in Health, Disease, and Aging?
Michal Schwartz et al.
JOURNAL OF NEUROSCIENCE (2013)
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
Michael T. Heneka et al.
NATURE (2013)
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2013)
Layer V cortical neurons require microglial support for survival during postnatal development
Masaki Ueno et al.
NATURE NEUROSCIENCE (2013)
Aging enhances classical activation but mitigates alternative activation in the central nervous system
Daniel C. Lee et al.
NEUROBIOLOGY OF AGING (2013)
Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer's Disease
Kurt M. Lucin et al.
NEURON (2013)
Review: Microglia of the aged brain: primed to be activated and resistant to regulation
D. M. Norden et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2013)
Review: Activation patterns of microglia and their identification in the human brain
D. Boche et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2013)
P2X7 receptor activation regulates microglial cell death during oxygen-glucose deprivation
Ukpong B. Eyo et al.
NEUROPHARMACOLOGY (2013)
Toll-Like Receptor 4 Antagonist Attenuates Intracerebral Hemorrhage-Induced Brain Injury
Yan-Chun Wang et al.
STROKE (2013)
A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
Isaac M. Chiu et al.
CELL REPORTS (2013)
Transcriptome analysis of amoeboid and ramified microglia isolated from the corpus callosum of rat brain
Rangarajan Parakalan et al.
BMC NEUROSCIENCE (2012)
Age related changes in microglial phenotype vary between CNS regions: Grey versus white matter differences
Adam D. Hart et al.
BRAIN BEHAVIOR AND IMMUNITY (2012)
Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein
Melanie B. Watson et al.
EXPERIMENTAL NEUROLOGY (2012)
A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease
Rashid Deane et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Innate immunity in the central nervous system
Richard M. Ransohoff et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
IL-4 in the Brain: A Cytokine To Remember
Sachin P. Gadani et al.
JOURNAL OF IMMUNOLOGY (2012)
Increased expression of Toll-like receptors 2 and 4 is associated with poor outcome in intracerebral hemorrhage
Manuel Rodriguez-Yanez et al.
JOURNAL OF NEUROIMMUNOLOGY (2012)
Rod microglia: elongation, alignment, and coupling to form trains across the somatosensory cortex after experimental diffuse brain injury
Jenna M. Ziebell et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage
Sen Lin et al.
JOURNAL OF NEUROINFLAMMATION (2012)
The Soluble Isoform of CX3CL1 Is Necessary for Neuroprotection in a Mouse Model of Parkinson's Disease
Josh M. Morganti et al.
JOURNAL OF NEUROSCIENCE (2012)
Mrp14 Deficiency Ameliorates Amyloid β Burden by Increasing Microglial Phagocytosis and Modulation of Amyloid Precursor Protein Processing
Markus P. Kummer et al.
JOURNAL OF NEUROSCIENCE (2012)
PPARγ/RXRα-Induced and CD36-Mediated Microglial Amyloid-β Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice
Mitsugu Yamanaka et al.
JOURNAL OF NEUROSCIENCE (2012)
Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor-γ-Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease
Shweta Mandrekar-Colucci et al.
JOURNAL OF NEUROSCIENCE (2012)
Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition
Paramita Chakrabarty et al.
MOLECULAR NEURODEGENERATION (2012)
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
Yaming Wang et al.
NATURE IMMUNOLOGY (2012)
Microglial activation in healthy aging
Alie Schuitemaker et al.
NEUROBIOLOGY OF AGING (2012)
INTRACEREBRAL MICROINJECTION OF INTERLEUKIN-4/INTERLEUKIN-13 REDUCES β-AMYLOID ACCUMULATION IN THE IPSILATERAL SIDE AND IMPROVES COGNITIVE DEFICITS IN YOUNG AMYLOID PRECURSOR PROTEIN 23 MICE
K. Kawahara et al.
NEUROSCIENCE (2012)
Thrombin and hemin as central factors in the mechanisms of intracerebral hemorrhage-induced secondary brain injury and as potential targets for intervention
Ranjith Babu et al.
NEUROSURGICAL FOCUS (2012)
Regulation of Macrophage Polarization and Wound Healing
Christopher J. Ferrante et al.
ADVANCES IN WOUND CARE (2012)
Toll-like Receptor 4 Contributes to Poor Outcome after Intracerebral Hemorrhage
Lauren H. Sansing et al.
ANNALS OF NEUROLOGY (2011)
Microglial calcium signal acts as a rapid sensor of single neuron damage in vivo
Gerhard Eichhoff et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Alternative activation of macrophages by IL-4 enhances the proteolytic capacity of their phagosomes through synergistic mechanisms
Dale R. Balce et al.
BLOOD (2011)
Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson's Disease
Hui-Ming Gao et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2011)
Iron toxicity in mice with collagenase-induced intracerebral hemorrhage
He Wu et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2011)
CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease
Mibel M. Pabon et al.
JOURNAL OF NEUROINFLAMMATION (2011)
TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease
Min Song et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment
Heather D. VanGuilder et al.
JOURNAL OF NEUROINFLAMMATION (2011)
CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity
Justin T. Rogers et al.
JOURNAL OF NEUROSCIENCE (2011)
Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo
Paramita Chakrabarty et al.
MOLECULAR NEURODEGENERATION (2011)
Fractalkine and CX3CR1 regulate hippocampal neurogenesis in adult and aged rats
Adam D. Bachstetter et al.
NEUROBIOLOGY OF AGING (2011)
Nitration of Tyrosine 10 Critically Enhances Amyloid β Aggregation and Plaque Formation
Markus P. Kummer et al.
NEURON (2011)
ROSIGLITAZONE DECREASES PEROXISOME PROLIFERATOR RECEPTOR-GAMMA LEVELS IN MICROGLIA AND INHIBITS TNF-ALPHA PRODUCTION: NEW EVIDENCES ON NEUROPROTECTION IN A PROGRESSIVE PARKINSON'S DISEASE MODEL
A. R. Carta et al.
NEUROSCIENCE (2011)
Switching the Microglial Harmful Phenotype Promotes Lifelong Restoration of Subtantia Nigra Dopaminergic Neurons from Inflammatory Neurodegeneration in Aged Mice
Francesca L'Episcopo et al.
REJUVENATION RESEARCH (2011)
Minocycline-Induced Attenuation of Iron Overload and Brain Injury After Experimental Intracerebral Hemorrhage
Fan Zhao et al.
STROKE (2011)
Molecular Pathophysiology of Cerebral Hemorrhage Secondary Brain Injury
Jaroslaw Aronowski et al.
STROKE (2011)
Subarachnoid Hemorrhage Induces Gliosis and Increased Expression of the Pro-inflammatory Cytokine High Mobility Group Box 1 Protein
Kentaro Murakami et al.
TRANSLATIONAL STROKE RESEARCH (2011)
The peroxisome proliferator-activated receptor: A family of nuclear receptors role in various diseases
Sandeep Tyagi et al.
JOURNAL OF ADVANCED PHARMACEUTICAL TECHNOLOGY & RESEARCH (2011)
Massive gliosis induced by interleukin-6 suppresses Aβ deposition in vivo: evidence against inflammation as a driving force for amyloid deposition
Paramita Chakrabarty et al.
FASEB JOURNAL (2010)
Innate Immunity and Neuroinflammation in the CNS: The Role of Microglia in Toll-Like Receptor-Mediated Neuronal Injury
Seija Lehnardt
GLIA (2010)
Molecular mechanisms of neurodegeneration in Alzheimer's disease
Leslie Crews et al.
HUMAN MOLECULAR GENETICS (2010)
IFN-γ Promotes Complement Expression and Attenuates Amyloid Plaque Deposition in Amyloid β Precursor Protein Transgenic Mice
Paramita Chakrabarty et al.
JOURNAL OF IMMUNOLOGY (2010)
α-Synuclein Activates Microglia by Inducing the Expressions of Matrix Metalloproteinases and the Subsequent Activation of Protease-Activated Receptor-1
Eun-Jung Lee et al.
JOURNAL OF IMMUNOLOGY (2010)
The role of microglia in amyloid clearance from the AD brain
C. Y. Daniel Lee et al.
JOURNAL OF NEURAL TRANSMISSION (2010)
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
Cameron R. Stewart et al.
NATURE IMMUNOLOGY (2010)
Regulation of Tau Pathology by the Microglial Fractalkine Receptor
Kiran Bhaskar et al.
NEURON (2010)
Decreased Clearance of CNS β-Amyloid in Alzheimer's Disease
Kwasi G. Mawuenyega et al.
SCIENCE (2010)
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Florent Ginhoux et al.
SCIENCE (2010)
Anti-Inflammatory Impact of Minocycline in a Mouse Model of Tauopathy
Claire J. Garwood et al.
Frontiers in Psychiatry (2010)
The complement cascade as a therapeutic target in intracerebral hemorrhage
Andrew F. Ducruet et al.
EXPERIMENTAL NEUROLOGY (2009)
Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: a time course study in a 6-hydroxydopamine model of Parkinson's disease
Lilia Marinova-Mutafchieva et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Neuroprotection of microglial conditioned medium on 6-hydroxydopamine-induced neuronal death: role of transforming growth factor beta-2
Elisabetta Polazzi et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloid-β
Alessandro Michelucci et al.
JOURNAL OF NEUROIMMUNOLOGY (2009)
Expression of complement system components during aging and amyloid deposition in APP transgenic mice
Julia Reichwald et al.
JOURNAL OF NEUROINFLAMMATION (2009)
Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV α-Synucleinopathy
Chee Yeun Chung et al.
JOURNAL OF NEUROSCIENCE (2009)
Activation of TLR4-Mediated NF kappa B Signaling in Hemorrhagic Brain in Rats
Weiyu Teng et al.
MEDIATORS OF INFLAMMATION (2009)
Neuroinflammation in the living brain of Parkinson's disease
Yasuomi Ouchi et al.
PARKINSONISM & RELATED DISORDERS (2009)
Hemin toxicity: a preventable source of brain damage following hemorrhagic stroke
Stephen R. Robinson et al.
REDOX REPORT (2009)
Hematoma Resolution as a Therapeutic Target The Role of Microglia/Macrophages
Xiurong Zhao et al.
STROKE (2009)
Alzheimer's disease
Alistair Burns et al.
BMJ-BRITISH MEDICAL JOURNAL (2009)
Toll-like receptor-4 and mitogen-activated protein kinase signal system are involved in activation of dendritic cells in patients with acute coronary syndrome
Lei Wang et al.
IMMUNOLOGY (2008)
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice
Fiona Pickford et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Cytokine-mediated inhibition of fibrillar amyloid-β peptide degradation by human mononuclear phagocytes
Masaru Yamamoto et al.
JOURNAL OF IMMUNOLOGY (2008)
JAK2-STAT3 signaling pathway mediates thrombin-induced proinflammatory actions of microglia in vitro
Chengfang Huang et al.
JOURNAL OF NEUROIMMUNOLOGY (2008)
Targeted Overexpression of Human α-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease
Shaji Theodore et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
Inflammatory Response in the Hippocampus of PS1M146L/APP751SL Mouse Model of Alzheimer's Disease: Age-Dependent Switch in the Microglial Phenotype from Alternative to Classic
Sebastian Jimenez et al.
JOURNAL OF NEUROSCIENCE (2008)
Microglial dysfunction and defective β-amyloid clearance pathways in aging Alzheimer's disease mice
Suzanne E. Hickman et al.
JOURNAL OF NEUROSCIENCE (2008)
Exploring the full spectrum of macrophage activation
David M. Mosser et al.
NATURE REVIEWS IMMUNOLOGY (2008)
The classical complement cascade mediates CNS synapse elimination
Beth Stevens et al.
CELL (2007)
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
Bahareh Ajami et al.
NATURE NEUROSCIENCE (2007)
Involvement of thrombin and mitogen-activated protein kinase pathways in hemorrhagic brain injury
Masatoshi Ohnishi et al.
EXPERIMENTAL NEUROLOGY (2007)
Interleukin-10 protects against inflammation-mediated degeneration of dopaminergic neurons in substantia nigra
Toyoko Arimoto et al.
NEUROBIOLOGY OF AGING (2007)
Inflammation after intracerebral hemorrhage
Jian Wang et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
Entry and distribution of microglial cells in human embryonic and fetal cerebral cortex
Anne Monier et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
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MOLECULAR BIOLOGY OF THE CELL (2007)
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NEUROSCIENCE (2007)
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NATURE NEUROSCIENCE (2006)
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GLIA (2006)
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JOURNAL OF NEUROINFLAMMATION (2006)
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NEUROBIOLOGY OF AGING (2006)
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NEUROBIOLOGY OF DISEASE (2006)
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NEUROCHEMICAL RESEARCH (2006)
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FASEB JOURNAL (2005)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
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JOURNAL OF NEUROCHEMISTRY (2003)
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MOLECULAR AND CELLULAR NEUROSCIENCE (2000)
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NEUROSCIENCE LETTERS (2000)
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JOURNAL OF NEUROCHEMISTRY (2000)
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JOURNAL OF NEUROSCIENCE (2000)
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NEUROSCIENCE LETTERS (2000)
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