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Andrea Crotti et al.
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Conceicao Bettencourt et al.
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Anabela Silva-Fernandes et al.
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Udo Rüb et al.
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Severine Boillee et al.
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BO Evert et al.
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Testing of SHIRPA, a mouse phenotypic assessment protocol, on Dmd(mdx) and Dmd(mdx3cv) dystrophin-deficient mice
JA Rafael et al.
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