相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The Incidence of Breast Cancer Recurrence 10-32 Years After Primary Diagnosis
Rikke Norgaard Pedersen et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2022)
PD-L1 interacts with Frizzled 6 to activate β-catenin and form a positive feedback loop to promote cancer stem cell expansion
Lingchen Fu et al.
ONCOGENE (2022)
Effect of Apatinib plus melatonin on vasculogenic mimicry formation by cancer stem cells from breast cancer cell line
Nazila Fathi Maroufi et al.
BREAST CANCER (2022)
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression
Meiyan Qi et al.
NATURE COMMUNICATIONS (2022)
Biglycan Promotes Cancer Stem Cell Properties, NFκB Signaling and Metastatic Potential in Breast Cancer Cells
Kanakaraju Manupati et al.
CANCERS (2022)
Cancer stem cell regulated phenotypic plasticity protects metastasized cancer cells from ferroptosis
Mingming Wu et al.
NATURE COMMUNICATIONS (2022)
LCOR mediates interferon-independent tumor immunogenicity and responsiveness to immune-checkpoint blockade in triple-negative breast cancer
Ivan Perez-Nunez et al.
NATURE CANCER (2022)
Development of an arteriolar niche and self-renewal of breast cancer stem cells by lysophosphatidic acid/protein kinase D signaling
Yinan Jiang et al.
COMMUNICATIONS BIOLOGY (2021)
The lingering mysteries of metastatic recurrence in breast cancer
Alessandra I. Riggio et al.
BRITISH JOURNAL OF CANCER (2021)
Breast cancer stem cells, heterogeneity, targeting therapies and therapeutic implications
Xiaobin Zeng et al.
PHARMACOLOGICAL RESEARCH (2021)
Dll1+ quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway
Sushil Kumar et al.
NATURE COMMUNICATIONS (2021)
A phase 1b study of the Notch inhibitor crenigacestat (LY3039478) in combination with other anticancer target agents (taladegib, LY3023414, or abemaciclib) in patients with advanced or metastatic solid tumors
Analia Azaro et al.
INVESTIGATIONAL NEW DRUGS (2021)
Single-cell transcriptomics reveal the heterogeneity and dynamic of cancer stem-like cells during breast tumor progression
Guojuan Jiang et al.
CELL DEATH & DISEASE (2021)
Signaling pathways governing breast cancer stem cells behavior
Kai Song et al.
STEM CELL RESEARCH & THERAPY (2021)
Development of antibodies against the notch ligand Delta-Like-1 by phage display with activity against breast cancer cells
Joana Sales-Dias et al.
NEW BIOTECHNOLOGY (2021)
Combining CD47 blockade with trastuzumab eliminates HER2-positive breast cancer cells and overcomes trastuzumab tolerance
Rosalynd Upton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Molecular correlates of response to eribulin and pembrolizumab in hormone receptor-positive metastatic breast cancer
Tanya E. Keenan et al.
NATURE COMMUNICATIONS (2021)
Adipsin-Dependent Secretion of Hepatocyte Growth Factor Regulates the Adipocyte-Cancer Stem Cell Interaction
Masahiro Mizuno et al.
CANCERS (2021)
Cancer Stem Cells: Emerging Key Players in Immune Evasion of Cancers
Martina Mang Leng Lei et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Breast Cancer Treatments: Updates and New Challenges
Anna Burguin et al.
JOURNAL OF PERSONALIZED MEDICINE (2021)
The Role of the Microenvironment and Immune System in Regulating Stem Cell Fate in Cancer
L. Paige Ferguson et al.
TRENDS IN CANCER (2021)
Cancer stem cell-targeted therapeutic approaches for overcoming trastuzumabresistance in HER2-positive breast cancer
Yan Qiu et al.
STEM CELLS (2021)
Targeting cancer stem cells for reversing therapy resistance: mechanism, signaling, and prospective agents
He-Ming Zhou et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)
Stem-like tumor cells involved in heterogeneous vasculogenesis in breast cancer
Yuling Mao et al.
ENDOCRINE-RELATED CANCER (2020)
Autophagy is essential for the endothelial differentiation of breast cancer stem-like cells
Ziang Yao et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2020)
Isolation and characterization of breast cancer stem cell-like phenotype by Oct4 promoter-mediated activity
Zahra Ghanei et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2020)
Identification of key genes controlling breast cancer stem cell characteristics via stemness indices analysis
Jianying Pei et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2020)
TNF-α increases breast cancer stem-like cells through up-regulating TAZ expression via the non-canonical NF-κB pathway
Wenjing Liu et al.
SCIENTIFIC REPORTS (2020)
Re-definition of claudin-low as a breast cancer phenotype
Christian Fougner et al.
NATURE COMMUNICATIONS (2020)
Translational control of breast cancer plasticity
Michael Jewer et al.
NATURE COMMUNICATIONS (2020)
Obesity and Breast Cancer: A Case of Inflamed Adipose Tissue
Ryan Kolb et al.
CANCERS (2020)
Cellular Plasticity in Breast Cancer Progression and Therapy
Deguang Kong et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2020)
Cancer Stem Cell Plasticity - A Deadly Deal
Archana P. Thankamony et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2020)
Phase Ib clinical trial of the anti-frizzled antibody vantictumab (OMP-18R5) plus paclitaxel in patients with locally advanced or metastatic HER2-negative breast cancer
Jennifer R. Diamond et al.
BREAST CANCER RESEARCH AND TREATMENT (2020)
Comprehensive characterization of claudin-low breast tumors reflects the impact of the cell-of-origin on cancer evolution
Roxane M. Pommier et al.
NATURE COMMUNICATIONS (2020)
Jagged1-Notch1-deployed tumor perivascular niche promotes breast cancer stem cell phenotype through Zeb1
Huimin Jiang et al.
NATURE COMMUNICATIONS (2020)
A novel HSP90 inhibitor targeting the C-terminal domain attenuates trastuzumab resistance in HER2-positive breast cancer
Jung Min Park et al.
MOLECULAR CANCER (2020)
Efficacy and biomarker analysis of CD133-directed CAR T cells in advanced hepatocellular carcinoma: a single-arm, open-label, phase II trial
Hanren Dai et al.
ONCOIMMUNOLOGY (2020)
miR-140-5p inhibits the proliferation and enhances the efficacy of doxorubicin to breast cancer stem cells by targeting Wnt1
Dawei Wu et al.
CANCER GENE THERAPY (2019)
Adipose-derived stem cells enhance human breast cancer growth and cancer stem cell-like properties through adipsin
Hideaki Goto et al.
ONCOGENE (2019)
Cognate Nonlytic Interactions between CD8+ T Cells and Breast Cancer Cells Induce Cancer Stem Cell-like Properties
Roland G. Stein et al.
CANCER RESEARCH (2019)
A multidisciplinary perspective on the subcutaneous administration of trastuzumab in HER2-positive breast cancer
S. Dent et al.
CURRENT ONCOLOGY (2019)
Targeting LIN28B reprograms tumor glucose metabolism and acidic microenvironment to suppress cancer stemness and metastasis
Chong Chen et al.
ONCOGENE (2019)
Knockdown of XB130 restrains cancer stem cell-like phenotype through inhibition of Wnt/β-Catenin signaling in breast cancer
Tian Xie et al.
MOLECULAR CARCINOGENESIS (2019)
An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
Marian L. Burr et al.
CANCER CELL (2019)
WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling
Shaojie Jiang et al.
CELL COMMUNICATION AND SIGNALING (2019)
Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers
Daisong Wang et al.
CELL RESEARCH (2019)
The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies
Lindsay Angus et al.
NATURE GENETICS (2019)
The FBXW2-MSX2-SOX2 axis regulates stem cell property and drug resistance of cancer cells
Yuan Yin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Breast cancer
Nadia Harbeck et al.
NATURE REVIEWS DISEASE PRIMERS (2019)
The Hedgehog Signaling Pathway: A Viable Target in Breast Cancer?
Priyanka Bhateja et al.
CANCERS (2019)
CD133 in Breast Cancer Cells: More than a Stem Cell Marker
Federica Brugnoli et al.
JOURNAL OF ONCOLOGY (2019)
BMP-4 enhances epithelial mesenchymal transition and cancer stem cell properties of breast cancer cells via Notch signaling
Sanghyuk Choi et al.
SCIENTIFIC REPORTS (2019)
Loss of Limb-Bud-and-Heart (LBH) attenuates mammary hyperplasia and tumor development in MMTV-Wnt1 transgenic mice
Kilan Ashad-Bishop et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
Cadherin 11 Inhibition Downregulates β-catenin, Deactivates the Canonical WNT Signalling Pathway and Suppresses the Cancer Stem Cell-Like Phenotype of Triple Negative Breast Cancer
Pamungkas Bagus Satriyo et al.
JOURNAL OF CLINICAL MEDICINE (2019)
Cancer stem-like cells directly participate in vasculogenic mimicry channels in triple-negative breast cancer
Huizhi Sun et al.
CANCER BIOLOGY & MEDICINE (2019)
ZEB1-repressed microRNAs inhibit autocrine signaling that promotes vascular mimicry of breast cancer cells
E. M. Langer et al.
ONCOGENE (2018)
Flubendazole overcomes trastuzumab resistance by targeting cancer stem-like properties and HER2 signaling in HER2-positive breast cancer
Yoon-Jae Kim et al.
CANCER LETTERS (2018)
HER2 Amplification in Tumors Activates PI3K/Akt Signaling Independent of HER3
Ana Ruiz-Saenz et al.
CANCER RESEARCH (2018)
CD10+ GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness
Shicheng Su et al.
CELL (2018)
JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance
Tianyi Wang et al.
CELL METABOLISM (2018)
Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia
Michael Y. Choi et al.
CELL STEM CELL (2018)
Quiescent Tissue Stem Cells Evade Immune Surveillance
Judith Agudo et al.
IMMUNITY (2018)
Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges
Ramesh Butti et al.
MOLECULAR CANCER (2018)
Leptin Signaling Mediates Obesity-Associated CSC Enrichment and EMT in Preclinical TNBC Models
Laura W. Bowers et al.
MOLECULAR CANCER RESEARCH (2018)
Adipocyte biology in breast cancer: From silent bystander to active facilitator
Junjeong Choi et al.
PROGRESS IN LIPID RESEARCH (2018)
TGFβ1 Promotes Breast Cancer Local Invasion and Liver Metastasis by Increasing the CD44high/CD24- Subpopulation
Chenjing Zhang et al.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2018)
The Notch Pathway in Breast Cancer Progression
Emmanuel N. Kontomanolis et al.
TheScientificWorldJOURNAL (2018)
Breast cancer stem cells characterized by CD70 expression preferentially metastasize to the lungs
Li Liu et al.
BREAST CANCER (2018)
STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion
Jung-Mao Hsu et al.
NATURE COMMUNICATIONS (2018)
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
Aurelie S. Cazet et al.
NATURE COMMUNICATIONS (2018)
MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state
Vittoria Poli et al.
NATURE COMMUNICATIONS (2018)
Quercetin Inhibits Breast Cancer Stem Cells via Downregulation of Aldehyde Dehydrogenase 1A1 (ALDH1A1), Chemokine Receptor Type 4 (CXCR4), Mucin 1 (MUC1), and Epithelial Cell Adhesion Molecule (EpCAM)
Rong Wang et al.
MEDICAL SCIENCE MONITOR (2018)
The Notch Pathway in Breast Cancer Progression
Emmanuel N. Kontomanolis et al.
Scientific World Journal (2018)
Breast fibroblasts in both cancer and normal tissues induce phenotypic transformation of breast cancer stem cells: a preliminary study
Bixiao Wang et al.
PEERJ (2018)
Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness
Maximilian Boesch et al.
ONCOIMMUNOLOGY (2018)
NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development
Vedrana Jelencic et al.
NATURE IMMUNOLOGY (2018)
VEGF-neuropilin-2 signaling promotes stem-like traits in breast cancer cells by TAZ-mediated repression of the Rac GAP β2-chimaerin
Ameer L. Elaimy et al.
SCIENCE SIGNALING (2018)
Stem-like Human Breast Cancer Cells Initiate Vasculogenic Mimicry on Matrigel
Yuki Izawa et al.
ACTA HISTOCHEMICA ET CYTOCHEMICA (2018)
NF-κB, inflammation, immunity and cancer: coming of age
Koji Taniguchi et al.
NATURE REVIEWS IMMUNOLOGY (2018)
Inflammatory breast cancer biology: the tumour microenvironment is key
Bora Lim et al.
NATURE REVIEWS CANCER (2018)
Immunization against HIF-1α Inhibits the Growth of Basal Mammary Tumors and Targets Mammary Stem Cells In Vivo
Denise L. Cecil et al.
CLINICAL CANCER RESEARCH (2017)
Inhibiting epidermal growth factor receptor signalling potentiates mesenchymal-epithelial transition of breast cancer stem cells and their responsiveness to anticancer drugs
Kanakaraju Manupati et al.
FEBS JOURNAL (2017)
Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells
Hung-Chang Chen et al.
IMMUNOLOGY AND CELL BIOLOGY (2017)
Nectin-4 is a breast cancer stem cell marker that induces WNT/β-catenin signaling via Pi3k/Akt axis
Sumit Siddharth et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2017)
CD49f Can Act as a Biomarker for Local or Distant Recurrence in Breast Cancer
Feng Ye et al.
JOURNAL OF BREAST CANCER (2017)
Cocktail treatment with EGFR-specific and CD133-specific chimeric antigen receptor-modified T cells in a patient with advanced cholangiocarcinoma
Kai-chao Feng et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
Vitamin D compounds inhibit cancer stem-like cells and induce differentiation in triple negative breast cancer
Naing Lin Shan et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2017)
Breast cancer targeted therapy: successes and challenges
[Anonymous]
LANCET (2017)
Trastuzumab emtansine versus treatment of physician's choice in patients with previously treated HER2-positive metastatic breast cancer (TH3RESA): final overall survival results from a randomised open-label phase 3 trial
Ian E. Krop et al.
LANCET ONCOLOGY (2017)
Interplay between CCR7 and Notch1 axes promotes stemness in MMTV-PyMT mammary cancer cells
Sarah T. Boyle et al.
MOLECULAR CANCER (2017)
Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a-LCOR axis
Toni Celia-Terrassa et al.
NATURE CELL BIOLOGY (2017)
VEGFA links self-renewal and metastasis by inducing Sox2 to repress miR-452, driving Slug
M. Kim et al.
ONCOGENE (2017)
Sox2 Communicates with Tregs Through CCL1 to Promote the Stemness Property of Breast Cancer Cells
Yingxi Xu et al.
STEM CELLS (2017)
Repurposing itraconazole as an anticancer agent
Hiroshi Tsubamoto et al.
ONCOLOGY LETTERS (2017)
MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists
Cong Lv et al.
NATURE COMMUNICATIONS (2017)
Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade
Maria Ouzounova et al.
NATURE COMMUNICATIONS (2017)
The association between obesity related adipokines and risk of breast cancer: a meta-analysis
Yu Gui et al.
ONCOTARGET (2017)
miR-600 Acts as a Bimodal Switch that Regulates Breast Cancer Stem Cell Fate through WNT Signaling
Rita El Helou et al.
CELL REPORTS (2017)
The Linkage between Breast Cancer, Hypoxia, and Adipose Tissue
Linda K. Rausch et al.
FRONTIERS IN ONCOLOGY (2017)
NF-kappaB Is Involved in the Regulation of EMT Genes in Breast Cancer Cells
Bruno R. B. Pires et al.
PLOS ONE (2017)
VEGF-A/Neuropilin 1 Pathway Confers Cancer Stemness via Activating Wnt/βCatenin Axis in Breast Cancer Cells
Lansheng Zhang et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)
Breast Cancer: Multiple Subtypes within a Tumor?
Syn Kok Yeo et al.
TRENDS IN CANCER (2017)
The non-canonical NF-κB pathway in immunity and inflammation
Shao-Cong Sun
NATURE REVIEWS IMMUNOLOGY (2017)
The Cargo Protein MAP17 (PDZK1IP1) Regulates the Cancer Stem Cell Pool Activating the Notch Pathway by Abducting NUMB
Jose Manuel Garcia-Heredia et al.
CLINICAL CANCER RESEARCH (2017)
Increased PD-L1 expression in breast and colon cancer stem cells
Yanheng Wu et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2017)
Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles
Pasquale Sansone et al.
CANCER RESEARCH (2017)
EpCAM expression in breast cancer cells is associated with enhanced bone metastasis formation
Toru Hiraga et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
Salinomycin induces selective cytotoxicity to MCF-7 mammosphere cells through targeting the Hedgehog signaling pathway
Ying-Zi Fu et al.
ONCOLOGY REPORTS (2016)
Stage-specific embryonic antigen-3 (SSEA-3) and β3GalT5 are cancer specific and significant markers for breast cancer stem cells
Sarah K. C. Cheung et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
MicroRNA Regulation of Human Breast Cancer Stem Cells
Yohei Shimono et al.
JOURNAL OF CLINICAL MEDICINE (2016)
Understanding EGFR Signaling in Breast Cancer and Breast Cancer Stem Cells: Overexpression and Therapeutic Implications
Ibrahim O Alanazi et al.
Asian Pacific Journal of Cancer Prevention (2016)
Let-7c blocks estrogen-activated Wnt signaling in induction of self-renewal of breast cancer stem cells
X. Sun et al.
CANCER GENE THERAPY (2016)
Disulfiram targets cancer stem-like properties and the HER2/Akt signaling pathway in HER2-positive breast cancer
Ji Young Kim et al.
CANCER LETTERS (2016)
Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling
Dongjun Peng et al.
CANCER RESEARCH (2016)
Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT
Srinivas Malladi et al.
CELL (2016)
Brachyury, a vaccine target, is overexpressed in triple-negative breast cancer
Duane H. Hamilton et al.
ENDOCRINE-RELATED CANCER (2016)
Trastuzumab-deBouganin Conjugate Overcomes Multiple Mechanisms of T-DM1 Drug Resistance
Rachelle L. Dillon et al.
JOURNAL OF IMMUNOTHERAPY (2016)
The combination of NVP-BKM120 with trastuzumab or RAD001 synergistically inhibits the growth of breast cancer stem cells in vivo
Feng Yu et al.
ONCOLOGY REPORTS (2016)
MYC regulates the antitumor immune response through CD47 and PD-L1
Stephanie C. Casey et al.
SCIENCE (2016)
In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors
Monica Benvenuto et al.
ONCOTARGET (2016)
Targeted gene silencing of CCL2 inhibits triple negative breast cancer progression by blocking cancer stem cell renewal and M2 macrophage recruitment
Wei Bin Fang et al.
ONCOTARGET (2016)
NF-kappaB-inducing kinase regulates stem cell phenotype in breast cancer
Karla Vazquez-Santillan et al.
SCIENTIFIC REPORTS (2016)
EMMPRIN Down-regulating miR-106a/b Modifies Breast Cancer Stem-like Cell Properties via Interaction with Fibroblasts Through STAT3 and HIF-1α
Yonglei Liu et al.
SCIENTIFIC REPORTS (2016)
Cancer stem cells and HER2 positive breast cancer: The story so far
Deep Shah et al.
GENES & DISEASES (2016)
A Novel Approach for Overcoming Drug Resistance in Breast Cancer Chemotherapy by Targeting new Synthetic Curcumin Analogues Against Aldehyde Dehydrogenase 1 (ALDH1A1) and Glycogen Synthase Kinase-3 β (GSK-3β)
Rajesh Kumar Kesharwani et al.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2015)
Adoptive T-cell therapy of prostate cancer targeting the cancer stem cell antigen EpCAM
Zhenling Deng et al.
BMC IMMUNOLOGY (2015)
The telomerase inhibitor imetelstat alone, and in combination with trastuzumab, decreases the cancer stem cell population and self-renewal of HER2+ breast cancer cells
Jillian E. Koziel et al.
BREAST CANCER RESEARCH AND TREATMENT (2015)
Prognosis of metastatic breast cancer: are there differences between patients with de novo and recurrent metastatic breast cancer?
D. J. A. Lobbezoo et al.
BRITISH JOURNAL OF CANCER (2015)
Genomic Analysis of Smoothened Inhibitor Resistance in Basal Cell Carcinoma
Hayley J. Sharpe et al.
CANCER CELL (2015)
Leptin and Adiponectin Modulate the Self-renewal of Normal Human Breast Epithelial Stem Cells
Raymond M. Esper et al.
CANCER PREVENTION RESEARCH (2015)
Wnt/ -Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
G.-B. Jang et al.
CANCER RESEARCH (2015)
Epithelial-Mesenchymal Plasticity of Breast Cancer Stem Cells: Implications for Metastasis and Therapeutic Resistance
Ming Luo et al.
CURRENT PHARMACEUTICAL DESIGN (2015)
Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche
Pegah Ghiabi et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Neutrophils support lung colonization of metastasis-initiating breast cancer cells
Stefanie K. Wculek et al.
NATURE (2015)
PIK3CAH1047R induces multipotency and multi-lineage mammary tumours
Shany Koren et al.
NATURE (2015)
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
Huimin Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling
Elisa Maria Memmi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
LGR5 Promotes Breast Cancer Progression and Maintains Stem-Like Cells Through Activation of Wnt/β-Catenin Signaling
Lu Yang et al.
STEM CELLS (2015)
FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer
Bingchen Han et al.
CELL REPORTS (2015)
Hedgehog Signaling in the Maintenance of Cancer Stem Cells
Catherine R. Cochrane et al.
CANCERS (2015)
VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2
D. Zhao et al.
ONCOGENE (2015)
β-Catenin Is Required for the Tumorigenic Behavior of Triple-Negative Breast Cancer Cells
Jinhua Xu et al.
PLOS ONE (2015)
Blockade of Wnt/β-catenin signaling suppresses breast cancer metastasis by inhibiting CSC-like phenotype
Gyu-Beom Jang et al.
SCIENTIFIC REPORTS (2015)
Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer
Jian Shi et al.
CANCER CELL (2014)
Metastatic Consequences of Immune Escape from NK Cell Cytotoxicity by Human Breast Cancer Stem Cells
Bin Wang et al.
CANCER RESEARCH (2014)
Targeting the NFκB Signaling Pathways for Breast Cancer Prevention and Therapy
Wei Wang et al.
CURRENT MEDICINAL CHEMISTRY (2014)
Sox2 promotes tamoxifen resistance in breast cancer cells
Marco Piva et al.
EMBO MOLECULAR MEDICINE (2014)
ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling
Rumela Chalcrabarti et al.
NATURE CELL BIOLOGY (2014)
A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages
Haihui Lu et al.
NATURE CELL BIOLOGY (2014)
Tackling the cancer stem cells - what challenges do they pose?
Diwakar R. Pattabiraman et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis
X. Lu et al.
ONCOGENE (2014)
A critical role of CD29 and CD49f in mediating metastasis for cancer-initiating cells isolated from a Brca1-associated mouse model of breast cancer
A. Vassilopoulos et al.
ONCOGENE (2014)
miR-27a regulates endothelial differentiation of breast cancer stem like cells
W. Tang et al.
ONCOGENE (2014)
Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells
M. F. Kendellen et al.
ONCOGENE (2014)
Endothelial Cells Provide a Notch-Dependent Pro-Tumoral Niche for Enhancing Breast Cancer Survival, Stemness and Pro-Metastatic Properties
Pegah Ghiabi et al.
PLOS ONE (2014)
Oct-4 and Nanog promote the epithelial-mesenchymal transition of breast cancer stem cells and are associated with poor prognosis in breast cancer patients
Dan Wang et al.
ONCOTARGET (2014)
miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway
Taichi Isobe et al.
ELIFE (2014)
Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States Reflective of their Normal Counterparts
Suling Liu et al.
STEM CELL REPORTS (2014)
Roles of microRNA-140 in stem cell-associated early stage breast cancer
Benjamin Wolfson
World Journal of Stem Cells (2014)
Nestin positively regulates the Wnt/β-catenin pathway and the proliferation, survival and invasiveness of breast cancer stem cells
Zuowei Zhao et al.
BREAST CANCER RESEARCH (2014)
Phase I dose-escalating study to evaluate the safety, tolerability, and pharmacokinetic and pharmacodynamic profiles of Foxy-5 in patients with metastatic breast, colorectal, or prostate cancer.
Peter Grundtvig Soerensen et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
A NIK-IKKα Module Expands ErbB2-Induced Tumor-Initiating Cells by Stimulating Nuclear Export of p27/Kip1
Weizhou Zhang et al.
CANCER CELL (2013)
Deadly crosstalk: Notch signaling at the intersection of EMT and cancer stem cells
Ingrid Espinoza et al.
CANCER LETTERS (2013)
Obesity Promotes Breast Cancer by CCL2-Mediated Macrophage Recruitment and Angiogenesis
Lisa M. Arendt et al.
CANCER RESEARCH (2013)
HER2 Drives Luminal Breast Cancer Stem Cells in the Absence of HER2 Amplification: Implications for Efficacy of Adjuvant Trastuzumab
Suthinee Ithimakin et al.
CANCER RESEARCH (2013)
Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity
Christine L. Chaffer et al.
CELL (2013)
Preclinical and Clinical Studies of Gamma Secretase Inhibitors with Docetaxel on Human Breast Tumors
Anne F. Schott et al.
CLINICAL CANCER RESEARCH (2013)
GLI1 regulates a novel neuropilin-2/61 integrin based autocrine pathway that contributes to breast cancer initiation
Hira Lal Goel et al.
EMBO MOLECULAR MEDICINE (2013)
Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells
Qiao Zheng et al.
ENDOCRINE-RELATED CANCER (2013)
miR-125b Functions as a Key Mediator for Snail-induced Stem Cell Propagation and Chemoresistance
Zixing Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer
Neil E. Bhola et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
CD133-targeted paclitaxel delivery inhibits local tumor recurrence in a mouse model of breast cancer
Suresh Kumar Swaminathan et al.
JOURNAL OF CONTROLLED RELEASE (2013)
Leptin increases HER2 protein levels through a STAT3-mediated up-regulation of Hsp90 in breast cancer cells
Cinzia Giordano et al.
MOLECULAR ONCOLOGY (2013)
Luminal breast cancer: from biology to treatment
Michail Ignatiadis et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2013)
BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers
Niamh E. Buckley et al.
NUCLEIC ACIDS RESEARCH (2013)
CD133+ cells with cancer stem cell characteristics associates with vasculogenic mimicry in triple-negative breast cancer
T. J. Liu et al.
ONCOGENE (2013)
Effect of CD44 Binding Peptide Conjugated to an Engineered Inert Matrix on Maintenance of Breast Cancer Stem Cells and Tumorsphere Formation
Xiaoming Yang et al.
PLOS ONE (2013)
Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response
Diane Tseng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
NF-kappa B non-cell-autonomously regulates cancer stem cell populations in the basal-like breast cancer subtype
Mizuki Yamamoto et al.
NATURE COMMUNICATIONS (2013)
Top Notch cancer stem cells by paracrine NF-κB signaling in breast cancer
Weizhou Zhang et al.
BREAST CANCER RESEARCH (2013)
Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance
Karthika Natarajan et al.
BIOCHEMICAL PHARMACOLOGY (2012)
CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells
Akihiro Tsuyada et al.
CANCER RESEARCH (2012)
CD44+/CD24-/low cancer stem/progenitor cells are more abundant in triple-negative invasive breast carcinoma phenotype and are associated with poor outcome
Michael O. Idowu et al.
HUMAN PATHOLOGY (2012)
Phase I Pharmacologic and Pharmacodynamic Study of the Gamma Secretase (Notch) Inhibitor MK-0752 in Adult Patients With Advanced Solid Tumors
Ian Krop et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+Breast Cancer by Expanding the Cancer Stem Cell Population
Hasan Korkaya et al.
MOLECULAR CELL (2012)
Comprehensive molecular portraits of human breast tumours
Daniel C. Koboldt et al.
NATURE (2012)
CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFβ signaling
P-K Lo et al.
ONCOGENE (2012)
Sox2 expression in breast tumours and activation in breast cancer stem cells
O. Leis et al.
ONCOGENE (2012)
Feedback upregulation of HER3 (ErbB3) expression and activity attenuates antitumor effect of PI3K inhibitors
Anindita Chakrabarty et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells
Douglas Edmund Feldman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia
Sarah J. Conley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Radiation-Induced Reprogramming of Breast Cancer Cells
Chann Lagadec et al.
STEM CELLS (2012)
TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer
Alejandra Bruna et al.
NATURE COMMUNICATIONS (2012)
Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma
Claudia Lengerke et al.
BMC CANCER (2011)
Let-7 family miRNAs regulate estrogen receptor alpha signaling in estrogen receptor positive breast cancer
Yingchun Zhao et al.
BREAST CANCER RESEARCH AND TREATMENT (2011)
Hedgehog Overexpression Is Associated with Stromal Interactions and Predicts for Poor Outcome in Breast Cancer
Sandra A. O'Toole et al.
CANCER RESEARCH (2011)
The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells
Michelangelo Cordenonsi et al.
CELL (2011)
Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape
Bernadett Papp et al.
CELL RESEARCH (2011)
Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype
Sara Ricardo et al.
JOURNAL OF CLINICAL PATHOLOGY (2011)
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling
Wei Tan et al.
NATURE (2011)
Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells
F. Xing et al.
ONCOGENE (2011)
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
Dimitrios Iliopoulos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Notch signalling in solid tumours: a little bit of everything but not all the time
Prathibha Ranganathan et al.
NATURE REVIEWS CANCER (2011)
Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture
Yi Arial Zeng et al.
CELL STEM CELL (2010)
Targeting Hedgehog - a Cancer Stem Cell Pathway
Akil A. Merchant et al.
CLINICAL CANCER RESEARCH (2010)
CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts
Christophe Ginestier et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Targeting Breast Cancer Stem Cells
Suling Liu et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis
Eva Gonzalez-Suarez et al.
NATURE (2010)
CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts
E. Marangoni et al.
BRITISH JOURNAL OF CANCER (2009)
A Novel Lung Metastasis Signature Links Wnt Signaling with Cancer Cell Self-Renewal and Epithelial-Mesenchymal Transition in Basal-like Breast Cancer
Theresa A. DiMeo et al.
CANCER RESEARCH (2009)
Epithelial-Mesenchymal Transitions in Development and Disease
Jean Paul Thiery et al.
CELL (2009)
Endothelial cell differentiation of human breast tumour stem/progenitor cells
Benedetta Bussolati et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
The lymphovascular embolus of inflammatory breast cancer expresses a stem cell-like phenotype
Yi Xiao et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
The mammary progenitor marker CD61/β3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis
Francois Vaillant et al.
CANCER RESEARCH (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
Mechanisms that mediate stem cell self-renewal and differentiation
Haojian Zhang et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2008)
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
Huafeng Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The CD44(+)/CD24(-) phenotype is enriched in basal-like breast tumors
Gabriella Honeth et al.
BREAST CANCER RESEARCH (2008)
IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland
Pasquale Sansone et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
Christophe Ginestier et al.
CELL STEM CELL (2007)
IκB kinase a kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells
Yixue Cao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Mechanisms of Disease: adipokines and breast cancer - endocrine and paracrine mechanisms that connect adiposity and breast cancer
Andreas Schaeffler et al.
NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM (2007)
Target practice: Lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancer
Maartje Los et al.
ONCOLOGIST (2007)
Ep-CAM expression in squamous cell carcinoma of the esophagus: a potential therapeutic target and prognostic marker
Nikolas H. Stoecklein et al.
BMC CANCER (2006)
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
Suling Liu et al.
CANCER RESEARCH (2006)
Diet induction of monocyte chemoattractant protein-1 and its impact on obesity
AR Chen et al.
OBESITY RESEARCH (2005)
The immunogenicity of human embryonic stem-derived cells
M Drukker et al.
TRENDS IN BIOTECHNOLOGY (2004)
EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy
WA Osta et al.
CANCER RESEARCH (2004)
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
Y Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
T Holbro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Monocyte chemoattractant protein 1 in obesity and insulin resistance
P Sartipy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
I Chambers et al.
CELL (2003)
Prospective identification of tumorigenic breast cancer cells
M Al-Hajj et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)