期刊
JOURNAL OF CLINICAL MEDICINE
卷 11, 期 12, 页码 -出版社
MDPI
DOI: 10.3390/jcm11123543
关键词
lidocaine; intravenous; analgesia; multi-modal anaesthesia; opioid-sparing
This narrative review provides an update on the applied pharmacology of lidocaine, its clinical scope in anaesthesia, novel concepts of analgesic and immune-modulatory effects as well as the current controversy around its use in perioperative opioid-sparing multi-modal strategies.
This narrative review provides an update on the applied pharmacology of lidocaine, its clinical scope in anaesthesia, novel concepts of analgesic and immune-modulatory effects as well as the current controversy around its use in perioperative opioid-sparing multi-modal strategies. Potential benefits of intravenous lidocaine in the context of cancer, inflammation and chronic pain are discussed against concerns of safety, toxicity and medico-legal constraints.
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