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Mediterranean Diet: The Beneficial Effects of Lycopene in Non-Alcoholic Fatty Liver Disease

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JOURNAL OF CLINICAL MEDICINE
卷 11, 期 12, 页码 -

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MDPI
DOI: 10.3390/jcm11123477

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lycopene; non-alcoholic fatty liver disease; Mediterranean diet; polyphenols; antioxidants activity; nutraceutics; natural compounds

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NAFLD is the most common chronic liver disease globally, with multiple factors contributing to its development. The Mediterranean diet and lycopene have shown beneficial effects in improving NAFLD.
Non-alcoholic fatty liver disease (NAFLD) presents the most common chronic liver disease globally; it is estimated that 25.24% of the world's population has NAFLD. NAFLD is a multi-factorial disease whose development involves various processes, such as insulin resistance, lipotoxicity, inflammation, cytokine imbalance, the activation of innate immunity, microbiota and environmental and genetic factors. Numerous clinical studies have shown that the Mediterranean diet produces beneficial effects in NAFLD patients. The aim of this review is to summarize the beneficial effects of lycopene, a soluble pigment found in fruit and vegetables, in NAFLD.

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