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Expression Analysis of CB2-GFP BAC Transgenic Mice
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BIOLOGICAL PSYCHIATRY (2014)
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EXPERT OPINION ON THERAPEUTIC TARGETS (2014)
Lack of seipin in neurons results in anxiety- and depression-like behaviors via down regulation of PPARγ
Libin Zhou et al.
HUMAN MOLECULAR GENETICS (2014)
A review of the relationship between proinflammatory cytokines and major depressive disorder
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Characterization of inflammation and immune cell modulation induced by low-dose LPS administration to healthy volunteers
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Hypoferremia of infection: a double-edged sword?
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NATURE MEDICINE (2014)
Identification of a unique TGF-β dependent molecular and functional signature in microglia
Oleg Butovsky et al.
NATURE NEUROSCIENCE (2014)
Polyunsaturated fatty acids and their metabolites in brain function and disease
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Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity
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Immunology of Major Depression
Norbert Mueller
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Monoacylglycerol Lipase Inhibition Blocks Chronic Stress-Induced Depressive-Like Behaviors via Activation of mTOR Signaling
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NEUROPSYCHOPHARMACOLOGY (2014)
Further evidence for the role of interferon-gamma on anxiety- and depressive-like behaviors: Involvement of hippocampal neurogenesis and NGF production
Alline C. Campos et al.
NEUROSCIENCE LETTERS (2014)
Neuroinflammation: The role and consequences
Monty Lyman et al.
NEUROSCIENCE RESEARCH (2014)
Lack of Association of P2RX7 Gene rs2230912 Polymorphism with Mood Disorders: A Meta-Analysis
Wen-Ping Feng et al.
PLOS ONE (2014)
Extracellular ATP acts as a damage-associated molecular pattern (DAMP) signal in plants
Kiwamu Tanaka et al.
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Effect of Anti-inflammatory Treatment on Depression, Depressive Symptoms, and Adverse Effects A Systematic Review and Meta-analysis of Randomized Clinical Trials
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JAMA PSYCHIATRY (2014)
Toll-like receptor 4: innate immune regulator of neuroimmune and neuroendocrine interactions in stress and major depressive disorder
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FRONTIERS IN NEUROSCIENCE (2014)
The Microglial α7-Acetylcholine Nicotinic Receptor Is a Key Element in Promoting Neuroprotection by Inducing Heme Oxygenase-1 via Nuclear Factor Erythroid-2-Related Factor 2
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ANTIOXIDANTS & REDOX SIGNALING (2013)
IFN-γ-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair
Gilad Kunis et al.
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Increased cerebrospinal fluid interleukin-6 levels in patients with schizophrenia and those with major depressive disorder
Daimei Sasayama et al.
JOURNAL OF PSYCHIATRIC RESEARCH (2013)
Role of the Toll Like Receptor (TLR) Radical Cycle in Chronic Inflammation: Possible Treatments Targeting the TLR4 Pathway
Kurt Lucas et al.
MOLECULAR NEUROBIOLOGY (2013)
Adenosine A2A receptor blockade reverts hippocampal stress-induced deficits and restores corticosterone circadian oscillation
V. L. Batalha et al.
MOLECULAR PSYCHIATRY (2013)
INFLAMMATORY CYTOKINES IN DEPRESSION: NEUROBIOLOGICAL MECHANISMS AND THERAPEUTIC IMPLICATIONS
J. C. Felger et al.
NEUROSCIENCE (2013)
Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors
Cecilia Csoelle et al.
PLOS ONE (2013)
Reduced phosphorylation of the mTOR signaling pathway components in the amygdala of rats exposed to chronic stress
Agata Chandran et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2013)
Nrf2 participates in depressive disorders through an anti-inflammatory mechanism
Maria Dolores Martin-de-Saavedra et al.
PSYCHONEUROENDOCRINOLOGY (2013)
Microglia-derived TNFα induces apoptosis in neural precursor cells via transcriptional activation of the Bcl-2 family member Puma
J. Guadagno et al.
CELL DEATH & DISEASE (2013)
A delicate balance: Iron metabolism and diseases of the brain
Dominic Hare et al.
FRONTIERS IN AGING NEUROSCIENCE (2013)
A Randomized Controlled Trial of the Tumor Necrosis Factor Antagonist Infliximab for Treatment-Resistant Depression
Charles L. Raison et al.
JAMA PSYCHIATRY (2013)
Involvement of NMDA receptors in the beneficial effects of pioglitazone on scopolamine-induced memory impairment in mice
Mina Almasi-Nasrabadi et al.
BEHAVIOURAL BRAIN RESEARCH (2012)
Functional roles of transferrin in the brain
Dominique F. Leitner et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2012)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
The immune system and developmental programming of brain and behavior
Staci D. Bilbo et al.
FRONTIERS IN NEUROENDOCRINOLOGY (2012)
IL-4 in the Brain: A Cytokine To Remember
Sachin P. Gadani et al.
JOURNAL OF IMMUNOLOGY (2012)
Ceruloplasmin deficiency results in an anxiety phenotype involving deficits in hippocampal iron, serotonin, and BDNF
Sarah J. Texel et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Sex differences in microglial colonization of the developing rat brain
Jaclyn M. Schwarz et al.
JOURNAL OF NEUROCHEMISTRY (2012)
WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway
Gohar Fakhfouri et al.
NEUROPHARMACOLOGY (2012)
Pioglitazone Adjunctive Therapy for Moderate-to-Severe Major Depressive Disorder: Randomized Double-Blind Placebo-Controlled Trial
Khatereh Sepanjnia et al.
NEUROPSYCHOPHARMACOLOGY (2012)
Endocannabinoids in nervous system health and disease: the big picture in a nutshell Introduction
Stephen D. Skaper et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2012)
Minocycline as adjunctive therapy for patients with unipolar psychotic depression: An open-label study
Tsuyoshi Miyaoka et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2012)
Peripheral innate immune challenge exaggerated microglia activation, increased the number of inflammatory CNS macrophages, and prolonged social withdrawal in socially defeated mice
Eric S. Wohleb et al.
PSYCHONEUROENDOCRINOLOGY (2012)
NMDA receptor involvement in antidepressant-like effect of pioglitazone in the forced swimming test in mice
Mohammad Salehi-Sadaghiani et al.
PSYCHOPHARMACOLOGY (2012)
The changing phenotype of microglia from homeostasis to disease
Xiao-Guang Luo et al.
TRANSLATIONAL NEURODEGENERATION (2012)
P2RX7 Gene Is Associated Consistently with Mood Disorders and Predicts Clinical Outcome in Three Clinical Cohorts
Pia Soronen et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2011)
Antidepressant-like effect of pioglitazone in the forced swimming test in mice: The role of PPAR-gamma receptor and nitric oxide pathway
Mohammad Salehi Sadaghiani et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: Advantages and limitations
Dustin K. Williams et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Cannabinoid Receptor and N-acyl Phosphatidylethanolamine Phospholipase D-Evidence for Altered Expression in Multiple Sclerosis
Hua Zhang et al.
BRAIN PATHOLOGY (2011)
Interleukin-6, a mental cytokine
Anneleen Spooren et al.
BRAIN RESEARCH REVIEWS (2011)
Suppression of nitric oxide synthesis by L-NAME reverses the beneficial effects of pioglitazone on scopolamine-induced memory impairment in mice
Nika Allami et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Iron and the immune system
Roberta J. Ward et al.
JOURNAL OF NEURAL TRANSMISSION (2011)
TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease
Min Song et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?
Johann Steiner et al.
JOURNAL OF NEUROINFLAMMATION (2011)
β-Adrenergic Receptor Antagonism Prevents Anxiety-Like Behavior and Microglial Reactivity Induced by Repeated Social Defeat
Eric S. Wohleb et al.
JOURNAL OF NEUROSCIENCE (2011)
The association between polyunsaturated fatty acids and depression among Iranian postgraduate students in Malaysia
Teymoor Yary et al.
LIPIDS IN HEALTH AND DISEASE (2011)
Stress responses: the contribution of prostaglandin E2 and its receptors
Tomoyuki Furuyashiki et al.
NATURE REVIEWS ENDOCRINOLOGY (2011)
Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and Neuroinflammation
Silvia Zoppi et al.
NEUROPSYCHOPHARMACOLOGY (2011)
RESILIENCE AND REDUCED C-FOS EXPRESSION IN P2X7 RECEPTOR KNOCKOUT MICE EXPOSED TO REPEATED FORCED SWIM TEST
A. A. Boucher et al.
NEUROSCIENCE (2011)
Increased cellular iron levels affect matrix metalloproteinase expression and phagocytosis in activated microglia
Nootchanat Mairuae et al.
NEUROSCIENCE LETTERS (2011)
Absence of Colony Stimulation Factor-1 Receptor Results in Loss of Microglia, Disrupted Brain Development and Olfactory Deficits
Bryna Erblich et al.
PLOS ONE (2011)
Immune system to brain signaling: Neuropsychopharmacological implications
Lucile Capuron et al.
PHARMACOLOGY & THERAPEUTICS (2011)
The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder
Courtney S. Jernigan et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2011)
The Hepcidin-Ferroportin System as a Therapeutic Target in Anemias and Iron Overload Disorders
Tomas Ganz et al.
HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM (2011)
Aberrant NF-KappaB Expression in Autism Spectrum Condition: A Mechanism for Neuroinflammation
Adam M. H. Young et al.
Frontiers in Psychiatry (2011)
Iron Homeostasis and the Inflammatory Response
Marianne Wessling-Resnick
ANNUAL REVIEW OF NUTRITION, VOL 30 (2010)
A Meta-Analysis of Cytokines in Major Depression
Yekta Dowlati et al.
BIOLOGICAL PSYCHIATRY (2010)
Interferon-gamma deficiency modifies the effects of a chronic stressor in mice: Implications for psychological pathology
Darcy Litteljohn et al.
BRAIN BEHAVIOR AND IMMUNITY (2010)
Depression-resistant endophenotype in mice overexpressing cannabinoid CB2 receptors
M. S. Garcia-Gutierrez et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Hematopoietic Origin of Pathological Grooming in Hoxb8 Mutant Mice
Shau-Kwaun Chen et al.
CELL (2010)
Mechanisms of brain iron transport: insight into neurodegeneration and CNS disorders
Eric Mills et al.
FUTURE MEDICINAL CHEMISTRY (2010)
The role of microglia in central nervous system immunity and glioma immunology
Isaac Yang et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2010)
TGF-β and LPS modulate ADP-induced migration of microglial cells through P2Y1 and P2Y12 receptor expression
Roberta De Simone et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways
Caterina Veroni et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2010)
Endocannabinoids Potentiate Synaptic Transmission through Stimulation of Astrocytes
Marta Navarrete et al.
NEURON (2010)
Inhibitory effects of SSRIs on IFN-gamma induced microglial activation through the regulation of intracellular calcium
Hideki Horikawa et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2010)
Transmembrane TNF-α: structure, function and interaction with anti-TNF agents
Takahiko Horiuchi et al.
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mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
Nanxin Li et al.
SCIENCE (2010)
Brain CB2 Receptors: Implications for Neuropsychiatric Disorders
Michelle Roche et al.
PHARMACEUTICALS (2010)
Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders
Ana M. Basso et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
Involvement of mTOR kinase in cytokine-dependent microglial activation and cell proliferation
Cinzia Dello Russo et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Interleukin-6 Is Elevated in the Cerebrospinal Fluid of Suicide Attempters and Related to Symptom Severity
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BIOLOGICAL PSYCHIATRY (2009)
Tumor Necrosis Factor alpha is Reparative via TNFR1 in the Hippocampus and via TNFR2 in the Striatum after Virus-Induced Encephalitis
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BRAIN PATHOLOGY (2009)
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DEPRESSION AND ANXIETY (2009)
Prostaglandin E receptor EP1 enhances GABA-mediated inhibition of dopaminergic neurons in the substantia nigra pars compacta and regulates dopamine level in the dorsal striatum
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EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
Oligodendrocytes and Myelination: The Role of Iron
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GLIA (2009)
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Sachiko Sato et al.
IMMUNOLOGICAL REVIEWS (2009)
Activation and Desensitization of Nicotinic α7-type Acetylcholine Receptors by Benzylidene Anabaseines and Nicotine
Roger L. Papke et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Neuroinflammation and Memory: The Role of Prostaglandins
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MOLECULAR NEUROBIOLOGY (2009)
Case-control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders
A. McQuillin et al.
MOLECULAR PSYCHIATRY (2009)
Adenosine A2A receptor mediates microglial process retraction
Anna G. Orr et al.
NATURE NEUROSCIENCE (2009)
Endocannabinoid signaling in microglial cells
Nephi Stella
NEUROPHARMACOLOGY (2009)
The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression
Michael Maes et al.
METABOLIC BRAIN DISEASE (2009)
Effect of R3487/MEM3454, a novel nicotinic α7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats
Amir H. Rezvani et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2009)
Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress
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PSYCHONEUROENDOCRINOLOGY (2009)
The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders
Elisabeth B. Binder
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Tumor necrosis factor and cancer, buddies or foes?
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ACTA PHARMACOLOGICA SINICA (2008)
Functional Expression of Brain Neuronal CB2 Cannabinoid Receptors Are Involved in the Effects of Drugs of Abuse and in Depression
Emmanuel S. Onaivi et al.
DRUG ADDICTION: RESEARCH FRONTIERS AND TREATMENT ADVANCES (2008)
LPS/TLR4 signal transduction pathway
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CYTOKINE (2008)
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EUROPEAN NEUROPSYCHOPHARMACOLOGY (2008)
Regulation of alternative macrophage activation by galectin-3
Alison C. MacKinnon et al.
JOURNAL OF IMMUNOLOGY (2008)
P2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients
Geza Nagy et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2008)
Therapeutic Potential of PPAR gamma Activation in Stroke
Raghu Vemuganti
PPAR RESEARCH (2008)
Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors
S. E. O'Sullivan
BRITISH JOURNAL OF PHARMACOLOGY (2007)
The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation
W. J. de Jonge et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Iron trafficking inside the brain
Torben Moos et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Tumor necrosis factor-alpha (TNF-α) regulates Toll-like receptor 2 (TLR2) expression in microglia
Mohsin Md. Syed et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Deficit of perineuronal oligodendrocytes in the prefrontal cortex in schizophrenia and mood disorders
Victor M. Vostrikov et al.
SCHIZOPHRENIA RESEARCH (2007)
Visualization of galectin-3 oligomerization on the surface of neutrophils and endothelial cells using fluorescence resonance energy transfer
Julie Nieminen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The P2Y12 receptor regulates microglial activation by extracellular nucleotides
Sharon E. Haynes et al.
NATURE NEUROSCIENCE (2006)
Introduction to NF-κB:: players, pathways, perspectives
T. D. Gilmore
ONCOGENE (2006)
The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression:: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine
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MOLECULAR PSYCHIATRY (2006)
Shortened onset of action of antidepressants in major depression using acetylsalicylic acid augmentation: a pilot open-label study
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INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY (2006)
Microglial α7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role
Tomohisa Suzuki et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2006)
PPAR-gamma agonists as regulators of microglial activation and brain inflammation
A Bernardo et al.
CURRENT PHARMACEUTICAL DESIGN (2006)
Cytokines sing the blues: inflammation and the pathogenesis of depression
CL Raison et al.
TRENDS IN IMMUNOLOGY (2006)
Brain nicotinic acetylcholine receptors: native subtypes and their relevance
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TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
Study of the localization of iron, ferritin, and hemosiderin in Alzheimer's disease hippocampus by analytical microscopy at the subcellular level
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JOURNAL OF STRUCTURAL BIOLOGY (2006)
Expression of P2X receptors on rat microglial cells during early development
ZH Xiang et al.
GLIA (2005)
Prostaglandin E receptor EP1 controls impulsive behavior under stress
Y Matsuoka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
ATP mediates rapid microglial response to local brain injury in vivo
D Davalos et al.
NATURE NEUROSCIENCE (2005)
LPS, TLR4 and infectious disease diversity
SI Miller et al.
NATURE REVIEWS MICROBIOLOGY (2005)
Cholinergic modulation of microglial activation by α7 nicotinic receptors
RD Shytle et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Upregulation of CB1 receptors and agonist-stimulated [35S]GTPγS binding in the prefrontal cortex of depressed suicide victims
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MOLECULAR PSYCHIATRY (2004)
A mechanism converting psychosocial stress into mononuclear cell activation
A Bierhaus et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Recognition of pathogen-associated molecular patterns by TLR family
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IMMUNOLOGY LETTERS (2003)
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