期刊
FRONTIERS IN ENDOCRINOLOGY
卷 13, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fendo.2022.924589
关键词
acromegaly; adenoma; pituitary; endonasal; endoscopic; skull-base; transnasal
资金
- Nell W. and William S. Elkin Research Fellowship in Oncology, Winship Cancer Institute, Emory University Hospital, Atlanta, GA
- National Center for Advancing Translational Sciences of the National Institutes of Health [UL1TR002378, TL1TR002382]
Acromegaly is a disease caused by excessive levels of growth hormone, usually due to hormone-secreting pituitary adenomas, leading to adverse effects in multiple systems. Diagnosis involves measuring serum growth hormone and IGF-1 levels and obtaining an MRI to evaluate pituitary adenoma function. Complete surgical resection of the growth hormone-secreting adenoma is the preferred treatment for acromegaly, aiming for biochemical remission. Medical and radiation therapies are available if biochemical cure is not achieved after surgery.
Acromegaly is a disease that occurs secondary to high levels of GH, most often from a hormone-secreting pituitary adenoma, with multisystem adverse effects. Diagnosis includes serum GH and IGF-1 levels, and obtaining an MRI pituitary protocol to assess for a functional pituitary adenoma. Attempted gross total resection of the GH-secreting adenoma is the gold standard in treatment for patients with acromegaly for a goal of biochemical remission. Medical and radiation therapies are available when patients do not achieve biochemical cure after surgical therapy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据