相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Insulin-like growth factor binding protein 1 ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease
Jiaqi Pan et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2021)
Parabrachial Interleukin-6 Reduces Body Weight and Food Intake and Increases Thermogenesis to Regulate Energy Metabolism
Devesh Mishra et al.
CELL REPORTS (2019)
The role of interleukin-6 in glucose homeostasis and lipid metabolism
Louise Lang Lehrskov et al.
SEMINARS IN IMMUNOPATHOLOGY (2019)
Different Responses to a High-Fat Diet in IL-6 Conditional Knockout Mice Driven by Constitutive GFAP-Cre and Synapsin 1-Cre Expression
Olaya Fernandez-Gayol et al.
NEUROENDOCRINOLOGY (2019)
The effect of non-TNF-targeted biologics and small molecules on insulin resistance in inflammatory arthritis
Francesco Ursini et al.
AUTOIMMUNITY REVIEWS (2018)
IL-6 Improves Energy and Glucose Homeostasis in Obesity via Enhanced Central IL-6 trans-Signaling
Katharina Timper et al.
CELL REPORTS (2017)
IL-6 ameliorates defective leptin sensitivity in DIO ventromedial hypothalamic nucleus neurons
Louise Larsen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2016)
The role of interleukin-6 signaling in nervous tissue
Michelle Rothaug et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
Chronic IL-6 Administration Desensitizes IL-6 Response in Liver, Causes Hyperleptinemia and Aggravates Steatosis in Diet-Induced-Obese Mice
Ana Luisa Gavito et al.
PLOS ONE (2016)
Amylin-Induced Central IL-6 Production Enhances Ventromedial Hypothalamic Leptin Signaling
Christelle Le Foll et al.
DIABETES (2015)
Interleukin-6 amplifies glucagon secretion: coordinated control via the brain and pancreas
Tammy M. Barnes et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2014)
Interleukin-6 and its receptors: A highly regulated and dynamic system
Janina Wolf et al.
CYTOKINE (2014)
Astrocyte-specific deficiency of interleukin-6 and its receptor reveal specific roles in survival, body weight and behavior
Albert Quintana et al.
BRAIN BEHAVIOR AND IMMUNITY (2013)
Metabolic Pitfalls of CNS Cre-Based Technology
Erika Harno et al.
CELL METABOLISM (2013)
Inter-relation between Interleukin (IL)-1, IL-6 and Body Fat Regulating Circuits of the Hypothalamic Arcuate Nucleus
E. Schele et al.
JOURNAL OF NEUROENDOCRINOLOGY (2013)
Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression
Kenneth R. Watterson et al.
NEUROSIGNALS (2013)
Interleukin 6 Deficiency Modulates the Hypothalamic Expression of Energy Balance Regulating Peptides during Pregnancy in Mice
Patricia Pazos et al.
PLOS ONE (2013)
Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and IL-6
Rozita Shirazi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Metformin ameliorates IL-6-induced hepatic insulin resistance via induction of orphan nuclear receptor small heterodimer partner (SHP) in mouse models
Y. D. Kim et al.
DIABETOLOGIA (2012)
Improvement of HbA1c during treatment with humanised anti-interleukin 6 receptor antibody, tocilizumab
Atsushi Ogata et al.
ANNALS OF THE RHEUMATIC DISEASES (2011)
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
Helga Ellingsgaard et al.
NATURE MEDICINE (2011)
Combined Neural Inactivation of Suppressor of Cytokine Signaling-3 and Protein-Tyrosine Phosphatase-1B Reveals Additive, Synergistic, and Factor-Specific Roles in the Regulation of Body Energy Balance
Nadege Briancon et al.
DIABETES (2010)
Human IL6 enhances leptin action in mice
M. Sadagurski et al.
DIABETOLOGIA (2010)
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance
V. B. Matthews et al.
DIABETOLOGIA (2010)
Liver-Specific Suppressor of Cytokine Signaling-3 Deletion in Mice Enhances Hepatic Insulin Sensitivity and Lipogenesis Resulting in Fatty Liver and Obesity
Nirupa Sachithanandan et al.
HEPATOLOGY (2010)
Differences in Wound Healing in Mice with Deficiency of IL-6 versus IL-6 Receptor
Molly M. McFarland-Mancini et al.
JOURNAL OF IMMUNOLOGY (2010)
Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice
Kanji Yamaguchi et al.
LABORATORY INVESTIGATION (2010)
Nestin-Cre Mice Are Affected by Hypopituitarism, Which Is Not Due to Significant Activity of the Transgene in the Pituitary Gland
Christophe Galichet et al.
PLOS ONE (2010)
Interleukin-6 Gene Knockout Influences Energy Balance Regulating Peptides in the Hypothalamic Paraventricular and Supraoptic Nuclei
A. Benrick et al.
JOURNAL OF NEUROENDOCRINOLOGY (2009)
Obesity and steatosis influence serum and hepatic inflammatory markers in chronic hepatitis C
Julie R. Jonsson et al.
HEPATOLOGY (2008)
Increased leptin expression selectively in the hypothalamus suppresses inflammatory markers CRP and IL-6 in leptin-deficient diabetic obese mice
Michael G. Dube et al.
PEPTIDES (2008)
IL-6 and IGF-1 are independent prognostic factors of liver steatosis and non-alcoholic steatohepatitis in morbidly obese patients
David Garcia-Galiano et al.
OBESITY SURGERY (2007)
Nestin-Cre transgenic mouse line Nes-Cre1 mediates highly efficient Cre/IoxP mediated recombination in the nervous system, kidney, and somite-derived tissues
Nicole C. Dubois et al.
GENESIS (2006)
Reduced stress- and cold-induced increase in energy expenditure in interleukin-6-deficient mice
Ingrid Wernstedt et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2006)
Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome
K Ueki et al.
HEPATOLOGY RESEARCH (2005)
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
DS Cai et al.
NATURE MEDICINE (2005)
Early changes in insulin secretion and action induced by high-fat diet are related to a decreased sympathetic tone
C Cruciani-Guglielmacci et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
Differential effects of interleukin-6 and-10 on skeletal muscle and liver insulin action in vivo
HJ Kim et al.
DIABETES (2004)
Interleukin 6 alleviates hepatic steatosis and ischemia/reperfusion injury in mice with fatty liver disease
F Hong et al.
HEPATOLOGY (2004)
Expression of interleukin-6 is greater in preadipocytes than in adipocytes of 3T3-L1 cells and C57BL/6J and ob/ob mice
JM Harkins et al.
JOURNAL OF NUTRITION (2004)
Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones:: PI3K dependent actin reorganization and KATP channel activation -: art. no. 54
S Mirshamsi et al.
BMC NEUROSCIENCE (2004)
Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse
K Ueki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion
I Leclerc et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)
Reduced exercise endurance in interleukin-6 deficient mice
J Fäldt et al.
ENDOCRINOLOGY (2004)
Interleukin-6 and tumor necrosis factor-α are not increased in patients with Type 2 diabetes:: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness
AL Carey et al.
DIABETOLOGIA (2004)
Nestin expression in pancreatic exocrine cell lineages
A Delacour et al.
MECHANISMS OF DEVELOPMENT (2004)
Interleukin-6 levels in the central nervous system are negatively correlated with fat mass in overweight/obese subjects
K Stenlöf et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
On the site and mechanism of action of the anti-obesity effects of interleukin-6
JO Jansson et al.
GROWTH HORMONE & IGF RESEARCH (2003)
Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40
Y Itoh et al.
NATURE (2003)
Intracerebroventricular interleukin-6 treatment decreases body fat in rats
K Wallenius et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Interleukin-6-deficient mice develop mature-onset obesity
V Wallenius et al.
NATURE MEDICINE (2002)
Raised interleukin-6 levels in obese patients
L Roytblat et al.
OBESITY RESEARCH (2000)